Schizophrenia [0.03%]
分裂症
René S Kahn,Iris E Sommer,Robin M Murray et al.
René S Kahn et al.
Schizophrenia is a chronic psychiatric disorder with a heterogeneous genetic and neurobiological background that influences early brain development, and is expressed as a combination of psychotic symptoms - such as hallucinations, delusions...
Retinoblastoma [0.03%]
视网膜母细胞瘤
Helen Dimaras,Timothy W Corson,David Cobrinik et al.
Helen Dimaras et al.
Retinoblastoma is a rare cancer of the infant retina that is diagnosed in approximately 8,000 children each year worldwide. It forms when both retinoblastoma gene (RB1) alleles are mutated in a susceptible retinal cell, probably a cone phot...
Colorectal cancer [0.03%]
结肠直肠癌
Ernst J Kuipers,William M Grady,David Lieberman et al.
Ernst J Kuipers et al.
Colorectal cancer had a low incidence several decades ago. However, it has become a predominant cancer and now accounts for approximately 10% of cancer-related mortality in western countries. The 'rise' of colorectal cancer in developed cou...
Stephen V Faraone,Philip Asherson,Tobias Banaschewski et al.
Stephen V Faraone et al.
Attention-deficit/hyperactivity disorder (ADHD) is a persistent neurodevelopmental disorder that affects 5% of children and adolescents and 2.5% of adults worldwide. Throughout an individual's lifetime, ADHD can increase the risk of other p...
Alain Fischer,Luigi D Notarangelo,Bénédicte Neven et al.
Alain Fischer et al.
Severe combined immunodeficiencies (SCIDs) comprise a group of rare, monogenic diseases that are characterized by an early onset and a profound block in the development of T lymphocytes. Given that adaptive immunity is abrogated, patients w...
IgA nephropathy [0.03%]
IgA肾病
Kar Neng Lai,Sydney C W Tang,Francesco Paolo Schena et al.
Kar Neng Lai et al.
Globally, IgA nephropathy (IgAN) is the most common primary glomerulonephritis that can progress to renal failure. The exact pathogenesis of IgAN is not well defined, but current biochemical and genetic data implicate overproduction of aber...
Systemic sclerosis [0.03%]
系统性硬化症
Yannick Allanore,Robert Simms,Oliver Distler et al.
Yannick Allanore et al.
Systemic sclerosis is a complex autoimmune disease characterized by a chronic and frequently progressive course and by extensive patient-to-patient variability. Like other autoimmune diseases, systemic sclerosis occurs more frequently in wo...
Venous thrombosis [0.03%]
静脉血栓形成
Alisa S Wolberg,Frits R Rosendaal,Jeffrey I Weitz et al.
Alisa S Wolberg et al.
Venous thromboembolism (VTE) encompasses deep-vein thrombosis (DVT) and pulmonary embolism. VTE is the leading cause of lost disability-adjusted life years and the third leading cause of cardiovascular death in the world. DVT leads to post-...
Vikas R Dharnidharka,Angela C Webster,Olivia M Martinez et al.
Vikas R Dharnidharka et al.
Post-transplant lymphoproliferative disorders (PTLDs) are a group of conditions that involve uncontrolled proliferation of lymphoid cells as a consequence of extrinsic immunosuppression after organ or haematopoietic stem cell transplant. PT...
Rachel Yehuda,Charles W Hoge,Alexander C McFarlane et al.
Rachel Yehuda et al.
Post-traumatic stress disorder (PTSD) occurs in 5-10% of the population and is twice as common in women as in men. Although trauma exposure is the precipitating event for PTSD to develop, biological and psychosocial risk factors are increas...