VEXAS syndrome [0.03%]
David B Beck,Sophie Georgin-Lavialle,Yohei Kirino et al.
David B Beck et al.
VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a disorder discovered in 2020 that bridges haematology, immunology and genetics. VEXAS syndrome arises from somatic mutations in UBA1, which encodes an E1 ubiquiti...
Insomnia disorder [0.03%]
失眠症
Kai Spiegelhalder,Chiara Baglioni,Charles M Morin et al.
Kai Spiegelhalder et al.
Insomnia disorder (ID) causes both night-time and daytime symptoms. Night-time symptoms include subjective difficulties initiating and maintaining sleep and early morning awakenings, whereas fatigue, perceived impairments in cognitive funct...
Lyme borreliosis [0.03%]
莱姆病
Franc Strle,Klemen Strle,Adriana Marques et al.
Franc Strle et al.
Lyme borreliosis is the most common tick-borne disease in the northern hemisphere. It is a zoonosis caused by several species of Borrelia burgdorferi sensu lato and transmitted by the bite of infected ticks of the Ixodes ricinus complex. Ly...
Type 2 diabetes mellitus [0.03%]
2型糖尿病
Melanie J Davies,Soo Lim,Tommy Slater et al.
Melanie J Davies et al.
Type 2 diabetes mellitus (T2DM) is a chronic, progressive disease driven by a complex interplay of genetic, biological, behavioural and social factors. The epidemiology of T2DM has shifted considerably, largely attributable to increasing ob...
Tuberous sclerosis complex [0.03%]
结节性硬化症综合征
Kellen Winden,E Martina Bebin,Shafali Jeste et al.
Kellen Winden et al.
Tuberous sclerosis complex (TSC) is a rare genetic disease caused by heterozygous loss-of-function variants in TSC1 or TSC2. Patients present with benign tumours known as hamartomas in the brain, eyes, lungs, kidneys, heart and skin. Many h...