Effectiveness of TNF inhibitors in patients with very early axial spondyloarthritis, defined as duration of ≤1 year of back pain: longitudinal observational data from the SCQM registry [0.03%]
英夫利昔单抗治疗病程小于等于1年的非常早期轴向型脊柱关节炎患者的有效性：SCQM登记处纵向观察数据的分析结果
Mauro Bachmann,Andrea Götschi,Annik Steimer et al.
Mauro Bachmann et al.
Objective: To characterise patients with 'very early' axial spondyloarthritis (axSpA), defined as a duration ≤1 year of back pain and to determine the effectiveness of a first tumour necrosis factor inhibitor (TNFi) in v...
Observational Study
RMD open. 2026 Mar 5;12(1):e006647. DOI:10.1136/rmdopen-2025-006647 2026
Impact of socioeconomic deprivation on risk and disease activity of Sjögren's disease [0.03%]
社会经济剥夺对Sjögren综合征风险和病情活动度的影响
Aliaksandra Baranskaya,Matilde Bandeira,Abdullah Nadeem et al.
Aliaksandra Baranskaya et al.
Background: We aimed to assess the impact of socioeconomic status (SES) on risk of Sjögren's disease (SjD) compared with non-Sjögren's Sicca and population controls, and on the clinical features of SjD. ...
Head and neck cancer risk in patients with rheumatoid arthritis compared with matched controls: a nationwide cohort study [0.03%]
与匹配对照组相比，类风湿性关节炎患者患头颈部癌症的风险：全国队列研究
Dagyeong Lee,Keun Hye Jeon,Jinhyung Jung et al.
Dagyeong Lee et al.
Objective: Autoimmune rheumatic diseases, including rheumatoid arthritis (RA), have recently been associated with an increased risk of cancer, particularly head and neck cancer (HNC). This study aimed to assess the risk o...
Relationship between ultrasound damage score of peripheral entheses and spinal bone formation in long-standing radiographic axial spondyloarthritis [0.03%]
超声外 entheseal 损伤评分与长期 X 线证实的轴向银屑病性脊柱关节炎骨形成之间的关系
Anna Deminger,Mats Geijer,Magnus Hallström et al.
Anna Deminger et al.
Objective: To assess structural changes at peripheral entheses and the association with spinal bone formation in patients with long-standing radiographic axial spondyloarthritis (r-axSpA) overall and stratified by sex. ...
Nipocalimab and certolizumab combination therapy in participants with active rheumatoid arthritis despite prior treatment with advanced therapies: results from the phase 2a DAISY-RA study [0.03%]
针对接受过先进治疗但类风湿关节炎仍处于活动期的受试者，尼波卡利单抗和赛妥珠单抗联合疗法的研究（来自DAISY-RA二期研究）
Peter C Taylor,Georg Schett,Tom W J Huizinga et al.
Peter C Taylor et al.
Objectives: To investigate the efficacy, safety, pharmacokinetics, immunogenicity and pharmacodynamics of combination therapy with nipocalimab and certolizumab in participants with active rheumatoid arthritis (RA) despite...
Clinical Trial
RMD open. 2026 Mar 4;12(1):e006464. DOI:10.1136/rmdopen-2025-006464 2026
Modified Dixon MRI to detect subclinical inflammation in clinically suspect arthralgia as a risk factor for rheumatoid arthritis development: should we image one or two hands? [0.03%]
改良Dixon磁共振成像用于检测临床疑似关节炎患者的亚临床炎症以评估其患类风湿性关节炎的风险：单侧手部还是双侧手部检查？
Daniek van der Kaaij,Stijn Claassen,Hanna W van Steenbergen et al.
Daniek van der Kaaij et al.
Objectives: MRI-detected subclinical inflammation in clinically suspect arthralgia (CSA) predicts progression to inflammatory arthritis (IA) and rheumatoid arthritis (RA) and is incorporated in EULAR/ACR risk stratificati...
[18F]FAPI PET/CT-based scoring systems for patient assessment in IgG4-related disease [0.03%]
IgG4相关性疾病患者评估的[18F]FAPI-PET/CT评分系统
Donghe Chen,Danqing Huang,Chuanyin Sun et al.
Donghe Chen et al.
Background: 18F-Fibroblast activation protein inhibitor ([18F]FAPI) positron emission tomography (PET)/CT is an emerging tool for detecting IgG4-related disease (IgG4-RD). However, standardised quantitative analysis and i...
Distinct pattern of comorbidities hinders treatment target attainment in SLE through persistent disease activity and delayed glucocorticoid tapering: longitudinal data from a multicentre cohort study [0.03%]
共病特征影响系统性红斑狼疮治疗目标的实现：来自多中心队列研究的纵向数据
Myrto Nikoloudaki,Georgios D Barmparis,Sofia Pitsigavdaki et al.
Myrto Nikoloudaki et al.
Background: Remission and low-disease activity are recommended targets in systemic lupus erythematosus (SLE), yet many patients fail to achieve them, underscoring the need to identify contributing barriers. We explored wh...
Multicenter Study
RMD open. 2026 Mar 4;12(1):e006424. DOI:10.1136/rmdopen-2025-006424 2026
Machine learning-based multiclass model for autoimmune disease diagnosis and classification through nailfold videocapillaroscopy features [0.03%]
基于机器学习的自身免疫疾病诊断和分类的多类别模型（通过甲襞视频毛细血管镜检查特征）
Jie Li,Congcong Jian,Jiaojiao Zhao et al.
Jie Li et al.
Objective: To develop and validate a predictive model for distinguishing controls (Ctr), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) based on nailfold videocapillaroscopy (NVC) image features. ...
CAR-T cell therapy for treatment-refractory rheumatic autoimmune diseases: a systematic review of clinical outcomes and safety profiles [0.03%]
治疗难治性风湿自身免疫性疾病CAR-T细胞疗法的临床疗效及安全性系统评价研究进展
Anindita Santosa,Tze Chin Tan
Anindita Santosa
Objectives: Current therapeutic paradigms for treatment-refractory rheumatic diseases rely on chronic immunosuppression with variable efficacy and potential for cumulative toxicity. We systematically synthesised evidence ...