Metachronous pancreatic cancer originating from disseminated founder pancreatic intraductal neoplasias (PanINs) [0.03%]
来源于播散性原位导管内乳头状黏液性肿瘤的异时性胰腺癌
Koji Imai,Hidenori Karasaki,Yusuke Ono et al.
Koji Imai et al.
Clonal populations originated from benign-looking 'founder cells' may spread widely within pancreas instead of being localized in situ before frank pancreatic ductal adenocarcinoma (PDA) can be detected. Metachronous PDA is not common event...
Novel association between microglia and stem cells in human gliomas: A contributor to tumour proliferation? [0.03%]
人胶质瘤中微胶质细胞与干细胞之间的新联系：肿瘤增殖的促成因素？
Imran Noorani,Gareth Petty,Paul L Grundy et al.
Imran Noorani et al.
Brain tumour stem cells and microglia both promote the growth of astrocytomas, the commonest form of primary brain tumour, with recent emerging evidence that these cell types may interact in glioma models. It is unclear whether microglia an...
High CerS5 expression levels associate with reduced patient survival and transition from apoptotic to autophagy signalling pathways in colorectal cancer [0.03%]
CerS5高表达与结直肠癌患者的生存率降低及凋亡向自噬信号途径转换相关性研究
Seán Fitzgerald,Katherine M Sheehan,Virginia Espina et al.
Seán Fitzgerald et al.
Ceramide synthase 5 is involved in the de novo synthesis of ceramide, a sphingolipid involved in cell death and proliferation. In this study, we investigated the role of ceramide synthase 5 in colorectal cancer by examining ceramide synthas...
Differential expression of argininosuccinate synthetase in serous and non-serous ovarian carcinomas [0.03%]
丝状和非丝状卵巢癌中精氨琥珀酸合成酶的差异表达
Dong-Joo Cheon,Ann E Walts,Jessica A Beach et al.
Dong-Joo Cheon et al.
The current standard of care for epithelial ovarian cancer does not discriminate between different histologic subtypes (serous, clear cell, endometrioid and mucinous) despite the knowledge that ovarian carcinoma subtypes do not respond unif...
Aurora A is a prognostic marker for breast cancer arising in BRCA2 mutation carriers [0.03%]
Aurora A可作为BRCA2突变携带者乳腺癌患者的预后标志物
Margret Aradottir,Sigridur T Reynisdottir,Olafur A Stefansson et al.
Margret Aradottir et al.
Overexpression of the Aurora A kinase has been shown to have prognostic value in breast cancer. Previously, we showed a significant association between AURKA gene amplification and BRCA2 mutation in breast cancer. The aim of this study was ...
Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium [0.03%]
乳腺癌组织微阵列中ER、PR、HER2、CK5 / 6和EGFR自动评分在乳腺癌协会联盟中的表现
William J Howat,Fiona M Blows,Elena Provenzano et al.
William J Howat et al.
Breast cancer risk factors and clinical outcomes vary by tumour marker expression. However, individual studies often lack the power required to assess these relationships, and large-scale analyses are limited by the need for high throughput...
Niek Hugen,Michiel Simons,Altuna Halilović et al.
Niek Hugen et al.
The increasing interest of the oncology community in tumour classification and prediction of outcome to targeted therapies has put emphasis on an improved identification of tumour types. Colorectal mucinous adenocarcinoma (MC) is a subtype ...
The Journal of Pathology: Clinical Research. A new step in the evolution of publishing in pathology [0.03%]
病理学杂志-临床研究。病理学出版物的新篇章
Peter Hall,Simon Herrington
Peter Hall
The prognosis of MYC translocation positive diffuse large B-cell lymphoma depends on the second hit [0.03%]
MYC易位阳性弥漫大B细胞淋巴瘤的预后取决于二次突变
Alexandra Clipson,Sharon Barrans,Naiyan Zeng et al.
Alexandra Clipson et al.
A proportion of MYC translocation positive diffuse large B-cell lymphomas (DLBCL) harbour a BCL2 and/or BCL6 translocation, known as double-hit DLBCL, and are clinically aggressive. It is unknown whether there are other genetic abnormalitie...
Gene Expression Profiling of Ewing Sarcoma Tumors Reveals the Prognostic Importance of Tumor-Stromal Interactions: A Report from the Children's Oncology Group [0.03%]
尤因肉瘤肿瘤的基因表达谱分析揭示了肿瘤-基质相互作用的预后重要性：来自儿童肿瘤学组的报告
Samuel L Volchenboum,Jorge Andrade,Lei Huang et al.
Samuel L Volchenboum et al.
Relapse of Ewing sarcoma (ES) can occur months or years after initial remission and salvage therapy for relapsed disease is usually ineffective. Thus, there is great need to develop biomarkers that can predict which patients are at risk for...