Synthesis and biocompatibility of a biodegradable and functionalizable thermo-sensitive hydrogel [0.03%]
一种可降解和官能化的温敏性水凝胶的合成及其生物相容性研究
Mantosh K Sinha,Jin Gao,Chelsea E T Stowell et al.
Mantosh K Sinha et al.
Injectable thermal gels are a useful tool for drug delivery and tissue engineering. However, most thermal gels do not solidify rapidly at body temperature (37°C). We addressed this by synthesizing a thermo-sensitive, rapidly biodegrading h...
Effects of the physicochemical properties of gold nanostructures on cellular internalization [0.03%]
金纳米结构的理化性质对细胞内吞的影响
Ningqiang Gong,Shizhu Chen,Shubin Jin et al.
Ningqiang Gong et al.
Unique physicochemical properties of Au nanomaterials make them potential star materials in biomedical applications. However, we still know a little about the basic problem of what really matters in fabrication of Au nanomaterials which can...
Effect of porosities of bilayered porous scaffolds on spontaneous osteochondral repair in cartilage tissue engineering [0.03%]
多孔双层结构支架多孔率对软骨组织工程中类组织形成的影响研究
Zhen Pan,Pingguo Duan,Xiangnan Liu et al.
Zhen Pan et al.
Poly(lactide-co-glycolide)-bilayered scaffolds with the same porosity or different ones on the two layers were fabricated, and the porosity effect on in vivo repairing of the osteochondral defect was examined in a comparative way for the fi...
Strategies for regeneration of components of nervous system: scaffolds, cells and biomolecules [0.03%]
神经系统成分再生策略：支架细胞及生物因子
Lingling Tian,Molamma P Prabhakaran,Seeram Ramakrishna
Lingling Tian
Nerve diseases including acute injury such as peripheral nerve injury (PNI), spinal cord injury (SCI) and traumatic brain injury (TBI), and chronic disease like neurodegeneration disease can cause various function disorders of nervous syste...
Next-generation resorbable polymer scaffolds with surface-precipitated calcium phosphate coatings [0.03%]
具有表面沉淀钙磷酸盐涂层的下一代可降解高分子支架
Jinku Kim,Maria Hanshella R Magno,Ophir Ortiz et al.
Jinku Kim et al.
Next-generation synthetic bone graft therapies will most likely be composed of resorbable polymers in combination with bioactive components. In this article, we continue our exploration of E1001(1k), a tyrosine-derived polycarbonate, as an ...
Drug carriers based on highly protein-resistant materials for prolonged in vivo circulation time [0.03%]
基于高蛋白抗性材料的药物载体用于延长体内循环时间
Ruiyuan Liu,Yan Li,Zhenzhong Zhang et al.
Ruiyuan Liu et al.
Long-circulating drug carriers are highly desirable in drug delivery system. However, nonspecific protein adsorption leaves a great challenge in drug delivery of intravenous administration and significantly affects both the pharmacokinetic ...
Distinctive effects of CD34- and CD133-specific antibody-coated stents on re-endothelialization and in-stent restenosis at the early phase of vascular injury [0.03%]
针对CD34和CD133特异性抗体包被支架对血管损伤早期再内皮化及贴壁内膜增生的影响不同
Xue Wu,Tieying Yin,Jie Tian et al.
Xue Wu et al.
It is not clear what effects of CD34- and CD133-specific antibody-coated stents have on re-endothelialization and in-stent restenosis (ISR) at the early phase of vascular injury. This study aims at determining the capabilities of different ...
Baolin Guo,Bo Lei,Peng Li et al.
Baolin Guo et al.
Tissue engineering scaffolds play a vital role in regenerative medicine. It not only provides a temporary 3-dimensional support during tissue repair, but also regulates the cell behavior, such as cell adhesion, proliferation and differentia...
pH-responsive hydrogel with dual-crosslinked network of polyvinyl alcohol/boric acid for controlled release of salvianolic acid B: novel pro-regenerative mechanisms in scar inhibition and wound healing [0.03%]
基于聚乙烯醇/硼酸双交联网络的ph响应性水凝胶控制释放丹参素b：伤口愈合和瘢痕抑制促再生新机制
This study investigates a novel pH-responsive hydrogel composed of polyvinyl alcohol (PVA) and boric acid (BA) designed for the controlled release of salvianolic acid B (SAB), addressing the critical challenge of scar formation and skin reg...