A 3D-printed modular magnetic digital microfluidic architecture for on-demand bioanalysis [0.03%]
按需生物分析的三维打印模块化磁性数字微流控体系结构
Pojchanun Kanitthamniyom,Aiwu Zhou,Shilun Feng et al.
Pojchanun Kanitthamniyom et al.
Magnetic digital microfluidics (MDM) manipulates fluids in the form of droplets on an open substrate, and incorporates surface energy traps (SETs) to facilitate the droplet manipulation. Conventional MDM devices are fabricated monolithicall...
Xiang Ren,Wonil Nam,Parham Ghassemi et al.
Xiang Ren et al.
This paper presents a new cell culture platform enabling label-free surface-enhanced Raman spectroscopy (SERS) analysis of biological samples. The platform integrates a multilayered metal-insulator-metal nanolaminated SERS substrate and pol...
Integrated sensing and delivery of oxygen for next-generation smart wound dressings [0.03%]
集成式供氧的感知与传输用于下一代智能创可贴
Manuel Ochoa,Rahim Rahimi,Jiawei Zhou et al.
Manuel Ochoa et al.
Chronic wounds affect over 6.5 million Americans and are notoriously difficult to treat. Suboptimal oxygenation of the wound bed is one of the most critical and treatable wound management factors, but existing oxygenation systems do not ena...
Fabien C Jammes,Sebastian J Maerkl
Fabien C Jammes
The immune system is a complex network of specialized cells that work in concert to protect against invading pathogens and tissue damage. Imbalances in this network often result in excessive or absent immune responses leading to allergies, ...
Infrared neural stimulation and inhibition using an implantable silicon photonic microdevice [0.03%]
使用可植入的硅光子微器件进行红外神经刺激和抑制
Ágoston Csaba Horváth,Sándor Borbély,Örs Csanád Boros et al.
Ágoston Csaba Horváth et al.
Brain is one of the most temperature sensitive organs. Besides the fundamental role of temperature in cellular metabolism, thermal response of neuronal populations is also significant during the evolution of various neurodegenerative diseas...
Highly stretchable and reliable graphene oxide-reinforced liquid gating membranes for tunable gas/liquid transport [0.03%]
具有高延展性和可靠性的氧化石墨烯增强型液态门控膜用于调节气体/液体传输
Wei Lv,Zhizhi Sheng,Yinglin Zhu et al.
Wei Lv et al.
The ability of membrane technologies to dynamically tune the transport behavior for gases and liquids is critical for their applications. Although various methods have been developed to improve membrane success, tradeoffs still exist among ...
Anti-biofouling NH3 gas sensor based on reentrant thorny ZnO/graphene hybrid nanowalls [0.03%]
基于回嵌式刺状ZnO/石墨烯复合纳米墙的抗污染NH3气体传感器
Tian Hang,Jiangming Wu,Shuai Xiao et al.
Tian Hang et al.
Since toxic gas leakage may cause ecological environmental problems and even life-threatening damage, effective monitoring of toxic gas is of great importance and subject to increasing demand. However, complicated environmental factors, as ...
A versatile microfluidic device for multiple ex vivo/in vitro tissue assays unrestrained from tissue topography [0.03%]
一种多用途微流控设备，适用于多种组织的离体/体外检测，不受组织形态限制
Jose M de Hoyos-Vega,Alan M Gonzalez-Suarez,Jose L Garcia-Cordero
Jose M de Hoyos-Vega
Precision-cut tissue slices are an important in vitro system to study organ function because they preserve most of the native cellular microenvironments of organs, including complex intercellular connections. However, during sample manipula...
Investigation of cell mechanics using single-beam acoustic tweezers as a versatile tool for the diagnosis and treatment of highly invasive breast cancer cell lines: an in vitro study [0.03%]
使用单光束声学镊子研究细胞力学作为诊断和治疗高度侵袭性乳腺癌细胞系的通用工具的体外研究
Hae Gyun Lim,Hsiao-Chuan Liu,Chi Woo Yoon et al.
Hae Gyun Lim et al.
Advancements in diagnostic systems for metastatic cancer over the last few decades have played a significant role in providing patients with effective treatment by evaluating the characteristics of cancer cells. Despite the progress made in...
Single-vesicle imaging quantifies calcium's regulation of nanoscale vesicle clustering mediated by α-synuclein [0.03%]
单囊泡成像定量分析α-突触核蛋白介导的钙离子对纳米尺度囊泡聚类的调控作用
Bin Cai,Jie Liu,Yunfei Zhao et al.
Bin Cai et al.
Although numerous studies have shown that the protein α-synuclein (α-Syn) plays a central role in Parkinson's disease, dementia with Lewy bodies, and other neurodegenerative diseases, the protein's physiological function remains poorly un...