Spheromatrix: a paper-based platform for scalable 3D tumor model generation, cryopreservation, and high-throughput drug assessment [0.03%]
球基质：一种用于生成、冷冻保存及高通量药物评估的纸基平台以构建可扩展性三维肿瘤模型
Ayoub Glia,Muhammedin Deliorman,Pavithra Sukumar et al.
Ayoub Glia et al.
Three-dimensional in vitro tumor models are increasingly recognized for their value in preclinical oncology, offering enhanced physiological relevance compared to traditional two-dimensional cultures. These systems improve the reliability o...
Oil-sealed RGD-modified alginate hydrogel microwell array for analysis of single-cell-derived extracellular vesicles and particles [0.03%]
一种用于分析单细胞来源的细胞外囊泡和颗粒的RGD修饰的海藻酸盐水凝胶微井阵列
Chisaki Yamagata,Yuto Hamazaki,Tomoharu Nakazato et al.
Chisaki Yamagata et al.
We propose an oil-sealed, arginine-glycine-aspartic (RGD) -modified alginate hydrogel microwell array for the analysis of single-cell-derived extracellular vesicles and particles (EVPs) secreted by adherent cells cultured in enclosed spaces...
Controllable-pore porous microneedles for high-speed extraction and biomarker detection of interstitial fluid [0.03%]
用于间质液高速提取和生物标志物检测的可控孔隙率微针阵列
Boyu Qin,Jongho Park,Sung Jae Kim et al.
Boyu Qin et al.
Porous microneedles have attracted considerable attention as minimally invasive tools for interstitial fluid sampling and biomarker analyses. However, existing porous microneedle fabrication methods often suffer from low extraction efficien...
Integrated 3D microstructured digital microfluidic platform for advanced 3D cell culture [0.03%]
用于先进三维细胞培养的集成3D微结构数字微流控平台
Xiaojun Chen,Xiaodong Lin,Haoran Li et al.
Xiaojun Chen et al.
Three-dimensional (3D) cell culture systems better simulate the in vivo microenvironment by promoting intercellular interactions and functional expression, which are crucial for tissue engineering and regenerative medicine. However, convent...
High-throughput chip-calorimeter using a Bi2Te3 thermopile heat flux sensor array [0.03%]
基于Bi2Te3热电堆阵列的高通量芯片量热仪
Yang Liu,Zhengguang Chen,Yushan Xie et al.
Yang Liu et al.
Modern thermoelectric modules have emerged as promising platforms for precision thermal analysis in biological and chemical applications. This study presents a high-throughput microcalorimeter employing a patterned bismuth telluride (Bi2Te3...
A surface acoustic wave tag utilizing a multilayer structure of SiO2/Pt/128°YX-LiNbO3 for operation at 600 °C [0.03%]
一种SiO2/Pt/128°YX-LN多层结构表面声波标签的600 ℃工作性能研究
Zhengkai Tang,Ruchuan Shi,Dapeng Guo et al.
Zhengkai Tang et al.
This study addresses the issue of traditional surface acoustic wave (SAW) tag failure under high-temperature conditions by proposing a SAW tag based on a multilayer structure of SiO2/Pt/128°YX-LiNbO3. The structure has been simulated using...
Side-viewing axicon-integrated miniature fiber probe for extended depth of focus and ultrahigh lateral resolution endoscopic imaging [0.03%]
用于延长焦深和超高横向分辨率内窥成像的侧视飞行器集成微型光纤探针
Yin Liu,Duanhong Zhang,Wenxin Li et al.
Yin Liu et al.
The early and precise diagnosis of suspected pathological tissues or organs has increasingly embraced the utilization of 3D real-time visualization and discrimination of intricate structures facilitated by miniature optical coherence tomogr...
Microelectrode arrays cultured with in vitro neural networks for motion control tasks: encoding and decoding progress and advances [0.03%]
体外神经网络与微电极阵列编码解码进展及在运动控制任务中的应用研究
Sihan Hua,Yaoyao Liu,Jinping Luo et al.
Sihan Hua et al.
Microelectrode arrays (MEAs) cultured with in vitro neural networks are gaining prominence in bio-integrated system research, owing to their inherent plasticity and emergent learning behaviors. Here, recent advances in motion control tasks ...
A three-dimensional bipolar microneedle electrode array with local ground integrated at each sidewall for enhanced focal electric stimulation [0.03%]
一种具有局部接地的一侧集成三维双极微针电极阵列用于增强聚焦电刺激
Seung-Han Chung,Chaesung Kim,Minju Kim et al.
Seung-Han Chung et al.
The need for spatially-confined electrical stimulation is growing in biomedical applications, for example intracortical stimulation and retinal implant, for enhancement of stimulating resolution. Local grounding techniques have been widely ...
Chengpeng Yao,Yaning Li,Hao Zhang et al.
Chengpeng Yao et al.
As semiconductor devices approach fundamental physical scaling limits, molecular electronics has emerged as a potential technological paradigm for sustaining Moore's Law through the capabilities of single-molecule-scale functional manipulat...