Impact of routine urine sodium evaluation on diuretic practices in patients with acute heart failure [0.03%]
常规评估尿钠对急性心力衰竭患者利尿剂使用的影响
Amitai Segev,Viana Copeland,David Mark Hochstein et al.
Amitai Segev et al.
Background and aims: Natriuresis-guided diuresis has been investigated in prospective trials for acute heart failure (HF), but its impact on diuretic prescribing in clinical practice is uncertain. ...
Use of sGC stimulators in heart failure therapy - a mode of action perspective [0.03%]
从作用模式角度谈sGC刺激剂在心力衰竭治疗中的应用
Frank Ruschitzka,Robert Lukowski,Stefano Corda et al.
Frank Ruschitzka et al.
Despite recent advances in pharmacological treatment, chronic heart failure (HF) is associated with significant morbidity and mortality, and further treatment options are needed. Intact nitric oxide (NO)-soluble guanylyl cyclase (sGC)-cycli...
The Quantitative Haemodynamic Effect of Levosimendan, Dobutamine and Milrinone in Heart Failure Patients: a Meta-Analysis [0.03%]
兰索拉唑、多巴胺和米力农在心力衰竭患者中的定量血流动力学效应的 meta 分析
Vincenzo Nuzzi,Cristina Madaudo,Paolo Manca et al.
Vincenzo Nuzzi et al.
Aims: Inotropic therapy is a cornerstone of medical treatment for patients with low-output heart failure (HF). We aimed to investigate the quantitative effect of specific inotropic drugs on invasive haemodynamics. ...
Inhibition of Adenosine Kinase Alleviates Hypertrophic Cardiomyopathy by Ameliorating Coronary Microvascular Dysfunction [0.03%]
腺苷激酶抑制通过改善冠状微血管功能缓解肥厚型心肌病
Fangfang Wan,Bingxuan Ma,Ziqiang Han et al.
Fangfang Wan et al.
Background: Hypertrophic cardiomyopathy (HCM) remains challenging with limited treatment options, the identification of novel therapeutic targets is urgently needed. ...
Worsening heart failure-based hierarchical endpoints beyond HF hospitalization: expert opinion paper [0.03%]
心力衰竭住院治疗之外的病情恶化的心力衰竭分层终点指标：专家意见稿
Agustín Fernández-Cisnal,Gema Miñana,Rafael de la Espriella et al.
Agustín Fernández-Cisnal et al.
The traditional, hospitalization-centric composite endpoint of cardiovascular (CV) death or time-to-first heart failure (HF) hospitalization is increasingly misaligned with contemporary HF care and, as evidence-based therapies lower event r...
Endothelial and inflammatory responses during ex vivo normothermic perfusion of human cardiac grafts [0.03%]
体外恒温灌注的人心脏移植的内皮和炎症反应
Alexandre Mansour,Nicolas Patou Parvedy,Juliette Ferrant et al.
Alexandre Mansour et al.
Aims: Normothermic ex vivo heart perfusion (NEVHP) allows functional assessment and preservation of donor hearts, but the biological responses occurring during perfusion are not well characterized. This pilot study evalua...
Metrics of Left Ventricular Active Relaxation Reflect Proteomic Myocardial Remodelling and Reverse Remodelling [0.03%]
左心室主动松弛指标反映蛋白组学心肌重塑和逆向重构
B A Barta,S Spiesshofer,M Ruppert et al.
B A Barta et al.
Aims: Pressure overload (PO) induces adverse myocardial remodelling, whereas efficient pressure unloading interventions can promote reverse remodelling at structural and molecular levels. This study seeks to identify a me...
Glucagon-Like Peptide-1 Receptor Agonists in Patients with Heart Failure with Reduced Ejection Fraction [0.03%]
射血分数降低的心力衰竭患者中的胰高血糖素样肽-1受体激动剂
Joseph Kassab,Mark H Drazner,Jennifer T Thibodeau
Joseph Kassab
Background: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) improve cardiovascular outcomes in obesity and HFpEF; however, their safety and efficacy in heart failure with reduced ejection fraction (HFrEF) remain unce...
Prognosis of Tricuspid Regurgitation after Mitral Transcatheter Edge-to-Edge Repair: The EXPANDed Studies [0.03%]
经导管二尖瓣缘对缘修复后三尖瓣反流的预后：EXPAND研究
Rodrigo Estevez-Loureiro,Mark J Ricciardi,Wolfgang Rottbauer et al.
Rodrigo Estevez-Loureiro et al.
Background: Transcatheter therapies offer new treatment options for patients with both mitral regurgitation (MR) and tricuspid regurgitation (TR). However, the optimal treatment pathway in patients with combined MR and TR...
Home-based body water monitoring and management system for heart failure patients using bioelectrical impedance analysis [0.03%]
基于生物电阻抗分析的家庭心力衰竭患者体液监测管理系统
Min Gyu Kong,Inki Moon,Jon Suh et al.
Min Gyu Kong et al.
Aims: This study evaluated the feasibility, acceptability, and clinical effectiveness of a home-based body water monitoring and preemptive management system using bioelectrical impedance analysis (BIA) in patients with he...