Real-world effectiveness of targeted therapies in ATTR cardiomyopathy: A meta-analysis integrating population-based data [0.03%]
靶向治疗在ATTR心肌病中的现实世界有效性：基于人群数据的meta分析
Alexios S Antonopoulos,Theodoros Tsampras,Dimitrios Terentes-Printzios et al.
Alexios S Antonopoulos et al.
Aims: The aim of this meta-analysis was to evaluate the effects of targeted treatments for transthyretin amyloid cardiomyopathy (ATTR-CM) on clinical outcomes by integrating clinical trial and real-world data. ...
Inflammation and genetics in myo-pericardial diseases: Insights from the Italian Study Group on Cardiomyopathies and Pericardial Diseases [0.03%]
心肌和心包病的炎症和遗传学：意大利心肌病和心包病研究小组的见解
Marco Merlo,Giulia Bassetto,Antonio Cannatà et al.
Marco Merlo et al.
In the past decade, advancements in knowledge on the immune system have partially unveiled the complex interplay between the heart and the immune system. This new branch of cardiology is now called cardio-immunology. It encompasses differen...
Economic burden of heart failure in Europe: A systematic review of costs and cost-effectiveness [0.03%]
欧洲心力衰竭的经济负担：成本和成本效益分析的系统评价
Josep Darbà,Meritxell Ascanio,Antonio Rodríguez et al.
Josep Darbà et al.
Heart failure (HF) affects over 64 million individuals worldwide and is a major cause of hospitalization and mortality, particularly among older adults. In Europe, HF imposes a significant and growing economic burden. This systematic review...
Indirect mitral annuloplasty in patients with reduced or preserved ejection fraction: A real-world, single-centre experience [0.03%]
射血分数降低或保留的心力衰竭患者间接性二尖瓣环成型术的临床效果分析
Holger Priebe-Brämer,Firas Jaly,Nithusa Rahunathan et al.
Holger Priebe-Brämer et al.
Aims: We aim to evaluate the real-world effectiveness and safety of the Carillon Mitral Contour System (CMCS) for indirect annuloplasty in patients with heart failure (HF) and secondary mitral regurgitation (SMR). ...
Guideline-directed medical therapy after revascularization and outcomes in ischaemic cardiomyopathy [0.03%]
血运重建术后缺血性心肌病患者的指南指导药物治疗及其疗效
Carlos Moliner-Abós,Maria Calvo-Barceló,Eduard Solé-Gonzalez et al.
Carlos Moliner-Abós et al.
Aims: Guideline-directed medical therapy (GDMT) remains the cornerstone for treating patients with heart failure (HF) and reduced ejection fraction (HFrEF) and coronary artery disease (CAD). However, real-world implementa...
Therapy gaps for patients with heart failure and reduced kidney function: A prospective cohort study [0.03%]
心力衰竭伴肾功能减退患者的治疗不足：一项前瞻性队列研究
Chen Hsiang Ma,Arthur Qi,Luke Gagnon et al.
Chen Hsiang Ma et al.
Aims: Despite emerging evidence for new pharmacotherapies to improve outcomes in patients with heart failure (HF) and kidney dysfunction, data on contemporary HF therapy use in this population are lacking. This study eval...
Determinants of diuresis/natriuresis following ambulatory intravenous loop diuretics for worsening heart failure [0.03%]
终末期心力衰竭患者口服与静脉袢利尿剂后利钠排尿的决定因素是一项随机交叉试验
Michael Massin,Guillaume Baudry,Kevin Duarte et al.
Michael Massin et al.
Background: The use of intravenous (IV) diuretics in an outpatient setting may represent an alternative to conventional hospitalization. Our objective was to identify factors associated with diuretic response during ambul...
Transcriptomic and proteomic profiling shows dysregulated immune and metabolic pathways in arrhythmogenic cardiomyopathy [0.03%]
转录组和蛋白质组特征分析显示心律失常性心肌病中免疫及代谢通路的失调
Deniz Akdis,Lukas Weidmann,Paolo Nanni et al.
Deniz Akdis et al.
Aims: Arrhythmogenic cardiomyopathy (ACM) is a hereditary heart disease characterized by fibrofatty myocardial replacement and a predisposition to malignant ventricular arrhythmias. The underlying pathomechanisms remain i...
Albuminuria is associated with worse outcomes in non-diabetics hospitalized with acute heart failure [0.03%]
急性心衰住院患者尿蛋白与不良临床结局相关性研究——来自ACUITY HF注册登记研究的数据
Yoshimitsu Takaoka,Yu Horiuchi,Michael Strader et al.
Yoshimitsu Takaoka et al.
Aims: Chronic kidney disease (CKD) increases the risk of morbidity and mortality in patients with heart failure (HF). Guidelines recommend assessing CKD using the urinary albumin-to-creatinine ratio (UACR), as albuminuria...