Virome diversity, evolution, transmission networks, and zoonotic potential of wildlife on the Qinghai-Tibet plateau [0.03%]
Hao Zhou,Ji Pu,Jinlv Liu et al.
Hao Zhou et al.
Wildlife serves as a natural reservoir for emerging viruses. Although virome studies of bats and rodents have advanced our understanding of viral diversity, the virome characteristics and zoonotic risks of wildlife inhabiting the Qinghai-Ti...
Yangyang Sun,Shunyao Wu,Zhenming Wu et al.
Yangyang Sun et al.
Colorectal cancer (CRC) continues to be a major global public health challenge. Extensive research has underscored the critical role of the gut microbiome for diagnostics of CRC. However, early-stage prediction of CRC, particularly at the p...
Multi-omics atlas of the bovine coronavirus-infected calf jejunum: reduction of Phocaeicola coprophilus and deoxycholic acid linked to Th17/Treg imbalance [0.03%]
Zheng Niu,Jingyi Xu,Xinfeng Hou et al.
Zheng Niu et al.
Optimal calf rearing is fundamental for ensuring efficient milk production. Bovine coronavirus (BCoV) poses a significant threat to calf health and leads to substantial economic losses in the dairy industry. However, the mechanisms by which...
Dietary grape pomace mitigates high-NSP-induced inflammation and production loss via microbiome-SCFA-immune mediated pathways [0.03%]
Milan K Sharma,Nikita Agarwal,Sara E Stadulis et al.
Milan K Sharma et al.
The United States poultry industry is transitioning away from antibiotic growth promoters (AGP) to antibiotic-free programs, which may increase the risk of chronic intestinal inflammation due to exposure to multiple factors. Grape pomace (G...
Gut microbiota-GABA axis dysregulation underlies polystyrene microplastic (PS-MP) neurotoxicity in rainbow trout: a role for oxidative stress and blood-brain barrier disruption [0.03%]
Fang Ma,Pan Zheng,Wenli Wang et al.
Fang Ma et al.
Microplastics (MPs) threaten aquatic ecosystems and pose potential risks to organismal health through bioaccumulation in aquatic species. This study reveals that 14-day exposure to 5 μm polystyrene microplastics (PS-MPs) (500 μg/L) induce...
Akkermansia muciniphila-derived 5-MIAA blunts colitis-associated tumorigenesis by modulating colonic SLC26A3/pSTAT3 signaling [0.03%]
Binhai Shen,Hongbin Liu,Weifeng Huang et al.
Binhai Shen et al.
The interaction between gut microbiota and host genetic factors has been implicated in the development of colitis-associated colorectal cancer (CAC). Although Akkermansia muciniphila (Akk) has been studied in CAC, its role and molecular mec...
Lung microbiota-mediated biotransformation of mogroside preserves pulmonary barrier integrity and attenuates PM2.5-induced inflammation via NF-κB-Th17 modulations [0.03%]
Kai Wang,Yuan Li,Cuiguang Li et al.
Kai Wang et al.
PM2.5-induced lung injury challenges poultry health with limited treatments. Mogroside's unique therapeutic impact on pulmonary inflammation may involve modulating the lung microbiome, which influences immune function and respiratory health...
Sex-specific microbial and tryptophan signatures of depression implicate archaeal methanogens and indole-3-acetic acid only in women [0.03%]
Anna Motger-Albertí,Laura Gallardo-Nuell,Marisel Rosell-Díaz et al.
Anna Motger-Albertí et al.
Sex differences in mental health are often overlooked, yet gut microbiota-host metabolite interactions may contribute to sexual dimorphism in depression. In a population-based cohort, we investigated sex-specific links among plasma tryptoph...
Intermittent fasting alleviates hyperalgesia in ovariectomized mice via gut microbiota remodeling [0.03%]
间歇性禁食通过重塑肠道菌群缓解卵巢切除小鼠的痛觉过敏现象
Rui-Feng Ao,Yu-Sheng Huang,Ying-Tao Hu et al.
Rui-Feng Ao et al.
Pain is a common symptom of menopause, yet effective therapeutic options are limited. Intermittent fasting (IF) has emerged as a promising dietary intervention; however, its effects on menopausal pain are still unclear. In this study, we es...
Gradient metapopulation microfluidic ecologies shape genetic and biofilm drivers of T4r phage resistance in E. coli [0.03%]
梯度元种群微流控生态系统可塑造大肠杆菌中T4r噬菌体抗性的遗传和生物膜驱动因素
Krisztina Nagy,Sarshad Koderi Valappil,Trung V Phan et al.
Krisztina Nagy et al.
We use a gradient microfluidic metapopulation ecology which generates non-uniform phage concentration gradients and micro-ecological niches to reveal the importance of time, spatial population structure and collective population dynamics in...