Gut microbiota-derived lactate is associated with disrupted cardiac circadian rhythms in alcoholic heart disease [0.03%]
肠道微生物群衍生的乳酸与酒精性心脏病中心脏生物钟紊乱有关
Wei Siang,Lin Wenji,Zhao Yiji et al.
Wei Siang et al.
Alcoholic Heart Disease (AHD) involves gut microbiota dysbiosis, metabolic disturbances, and circadian disruption, yet their interconnections remain unclear. Using a murine AHD model, we integrated echocardiography, metabolomics, cardiac tr...
Cetobacterium somerae as a microbial correlate of improved muscle quality after intestinal microbiota transplantation in Yellow River carp (Cyprinus carpio) [0.03%]
黄河鲤鱼肠道菌群移植改善肌肉品质与Cetobacterium somerae相关性研究
Lijiao Cheng,Yijie Li,Yujie Zhang et al.
Lijiao Cheng et al.
Dietary faba bean enhances fish muscle quality but concurrently reduces growth performance. The gut microbiota critically modulates muscle growth and quality. However, the specific microbial taxa, metabolites, and regulatory mechanisms resp...
An antifungal effector from a plant-parasitic nematode modulates host fungal community composition and supports ecological fitness [0.03%]
植物寄生线虫的抗真菌效应子可调节宿主真菌群落组成并提高其生态适应性
Dong-Zhen Li,Yongxia Li,Xuan Wang et al.
Dong-Zhen Li et al.
Host-associated microbiomes are increasingly recognized as key determinants of plant health, disease development, and ecosystem functioning. Plant pathogens, especially fungal pathogens, have been reported to secrete antimicrobial effectors...
The role and possible mechanism of intestinal fungi in the progression of chronic liver diseases [0.03%]
肠道真菌在慢性肝病进展中的作用及可能机制
Yirui Hu,Ye Yang,Shuyan Wang et al.
Yirui Hu et al.
Chronic liver disease (CLD) causes 2 million annual deaths (4% of all global deaths). While gut bacteria are widely studied, intestinal fungi remain largely overlooked despite their critical roles in maintaining microecological homeostasis....
Specific gut microbes are associated with the incidence of cardiometabolic disease in the HELIUS cohort [0.03%]
特定肠道微生物与HELIUS队列中代谢性心血管疾病发病的关联研究
Barbara J H Verhaar,Thomas A Bouwmeester,Henrike Galenkamp et al.
Barbara J H Verhaar et al.
Associations between the gut microbiota and cardiometabolic health are well established, but evidence from longitudinal studies remains limited. In the prospective multi-ethnic HELIUS cohort, we investigated whether baseline gut microbiota ...
Soil acidification dismantles a citrulline-mediated microbe-metabolite-host defense axis in watermelon, exacerbating Fusarium wilt [0.03%]
土壤酸化破坏了瓜类果实中的精氨抗氧化防御系统，加重萎蔫病危害
Zewen Zhang,Leyu Yu,Chunlin Wu et al.
Zewen Zhang et al.
Soil acidification disrupts the structure and function of soil microbiomes, resulting in increased vulnerability to soil-borne pathogens. While the link between soil acidification and disease susceptibility is well-established, the mechanis...
Trehalose ameliorates severe acute pancreatitis by modulating gut microbial metabolism [0.03%]
海藻糖通过调节肠道菌群代谢改善急性重症胰腺炎
Haibin Hao,Deren Du,Hong Lin et al.
Haibin Hao et al.
This study investigates the role of trehalose in modulating gut microbiota metabolism and alleviating symptoms of severe acute pancreatitis (SAP). Here, we found that gut microbial metabolism was imbalanced in SAP. In particular, we observe...
Dietary copper-driven colonic dysbiosis mediates oxidative stress and butyrate deficiency to facilitate the spread of resistome in pigs [0.03%]
膳食铜通过结肠菌群失调介导氧化应激和丁酸缺乏促进猪肠道抗性基因扩增及传播
Yang Wen,Meng Gao,Zhenyu Wang et al.
Yang Wen et al.
Copper-induced transmission of antimicrobial resistance has been well documented in livestock farming environments, but the in vivo mechanisms driving fecal resistome development remain unclear. Here, 120 mg/kg CuSO4 and copper-peptide were...
Disruption of IgA-mediated aggregation at weaning favors mucus encroachment by commensal bacteria [0.03%]
IgA介导的免疫耐受在断奶期被破坏导致共生菌黏附于粘膜组织
Kevin Simpson,Renaud Baillou,Tiphaine Le Roy et al.
Kevin Simpson et al.
Disruption of the gut mucus barrier is critical in the development of infectious or chronic inflammatory diseases. The suckling-to-weaning transition is pivotal to the barrier maturation and is associated with a high incidence of gastrointe...
Colouring dysbiosis: FetB-dependent Mn-PPIX produced by Porphyromonas gingivalis shapes the oral microbiota [0.03%]
口膜菌FetB依赖性Mn-原卟啉IX塑造口腔微生物群
Yupaporn Phonok,Alysha Pyne,Siyuan Liu et al.
Yupaporn Phonok et al.
Polymicrobial diseases, such as periodontitis, are shaped by microbial interactions and nutrient‑responsive metabolic adaptations. Here, we identify novel porphyrin pigments produced by Porphyromonas gingivalis in response to haemoglobin c...