Jeffrey A Cohen,Ho Jin Kim,Mar Tintore
Jeffrey A Cohen
Incidence of AQP4-IgG seropositive neuromyelitis optica spectrum disorders in the Netherlands: About one in a million [0.03%]
荷兰国家人群中的水通道蛋白4-IgG阳性神经脊髓炎谱系疾病患病率约为百万分之一
E Daniëlle van Pelt,Yu Yi M Wong,Immy A Ketelslegers et al.
E Daniëlle van Pelt et al.
Neuromyelitis optica (NMO) is a rare autoimmune disease affecting the optic nerves and spinal cord. In the majority of NMO patients anti-aquaporin-4 antibodies (AQP4-IgG) are detected. Here we assessed a nationwide incidence of AQP4-IgG-ser...
Predicting optimal response to B-cell depletion with rituximab in multiple sclerosis using CXCL13 index, magnetic resonance imaging and clinical measures [0.03%]
使用CXCL13指数、磁共振成像和临床指标预测利妥昔单抗治疗多发性硬化症的最优反应
Enrique Alvarez,Laura Piccio,Robert J Mikesell et al.
Enrique Alvarez et al.
Background: B-cell depleting drugs show promise for treating multiple sclerosis. Objective: We sought predictors of optimal response to...
Improvement to baseline after plasma exchange in spinal attacks associated with neuromyelitis optica [0.03%]
与视神经脊髓炎相关的脊髓发作在血浆置换治疗后的改善状况评估
Mickael Bonnan,Philippe Cabre
Mickael Bonnan
Free kappa light chains in cerebrospinal fluid as a biomarker to assess risk conversion to multiple sclerosis [0.03%]
脑脊液中游离κ轻链作为生物标志物评估多发性硬化症风险的转换
P Menéndez-Valladares,M I García-Sánchez,P Cuadri Benítez et al.
P Menéndez-Valladares et al.
Background: Multiple sclerosis (MS) initiates with a first attack or clinically isolated syndrome (CIS). The importance of an early treatment in MS leads to the search, as soon as possible, for novel biomarkers which can ...
A randomized trial of teriflunomide added to glatiramer acetate in relapsing multiple sclerosis [0.03%]
特立氟咪酯与醋酸格拉默联合治疗复发性多发性硬化症的随机临床试验
M S Freedman,J S Wolinsky,P Truffinet et al.
M S Freedman et al.
Background: Teriflunomide is a once-daily oral immunomodulator for the treatment of relapsing-remitting MS. Objective: To evaluate the ...
Remotely-delivered cognitive remediation in multiple sclerosis (MS): protocol and results from a pilot study [0.03%]
多发性硬化症（MS）的远程认知康复方案及一项试点研究结果
L E Charvet,M T Shaw,L Haider et al.
L E Charvet et al.
Background: Cognitive impairment represents a critical unmet treatment need in multiple sclerosis (MS). Cognitive remediation is promising but traditionally requires multiple clinic visits to access treatment. Computer-ba...
Evaluation of an integrated multidisciplinary approach in multiple sclerosis care: A prospective, randomized, controlled study [0.03%]
多发性硬化综合诊疗方法的评估：一项前瞻性随机对照研究
Caroline Papeix,Laetitia Gambotti,Rana Assouad et al.
Caroline Papeix et al.
Background: Disabled multiple sclerosis (MS) patients often need intervention of multiple specialists, resulting in a complex organization of care. How this multidisciplinary care should be organized and structured has no...
Improved working ability in a contemporary MS population compared with a historic non-treated MS population in the same geographic area of Sweden [0.03%]
与同一地理区域未接受治疗的多发性硬化症患者相比，瑞典当代多发性硬化症患者的改善工作能力
Anne Wickström,Peter Sundström,Lucas Wickström et al.
Anne Wickström et al.
Background: Multiple sclerosis (MS) often causes a reduced ability to work. Improved disease control as well as adjustment of working conditions may improve work ability in MS. ...
Detection of cortical lesions in multiple sclerosis: A new imaging approach [0.03%]
一种新的成像方法在多发性硬化皮质病变检测中的应用研究
Kevin R Patel,Jie Luo,Enrique Alvarez et al.
Kevin R Patel et al.
Cortical lesions occur early in multiple sclerosis (MS) and are thought to have clinical implications. Conventional MRI is insensitive to cortical pathology. Investigational imaging modalities show improved but incomplete cortical lesion de...