Challenges in the diagnosis and treatment of CNS demyelinating disorders in Zambia [0.03%]
赞比亚中枢神经系统脱髓鞘疾病的诊断和治疗挑战
Dhanashri P Miskin,Altaf Saadi,Laston Chikoya et al.
Dhanashri P Miskin et al.
Demyelinating disease occurs in a population of black adult Zambians whose genetic and environmental risk factors for multiple sclerosis are thought to be rare. The diagnosis of demyelinating disease was based predominantly on compatible cl...
Francois H Jacques,Brian T Harel,Adrian J Schembri et al.
Francois H Jacques et al.
Background: Cognitive dysfunction affects up to 65% of multiple sclerosis (MS) patients and progresses over time. Natalizumab has been shown to be superior to placebo in preserving cognition for the first two years of the...
Relationship between timed 25-foot walk and diffusion tensor imaging in multiple sclerosis [0.03%]
timed 25英尺步行与多发性硬化患者的弥散张量成像之间的关系
Sylvia Klineova,Rebecca Farber,Catarina Saiote et al.
Sylvia Klineova et al.
Objective/background: The majority of multiple sclerosis patients experience impaired walking ability, which impacts quality of life. Timed 25-foot walk is commonly used to gauge gait impairment but results can be broadly...
Distractibility in multiple sclerosis: The role of depression [0.03%]
抑郁症在多发性硬化症 distractibility（注意力分散）中的作用
Viral P Patel,Aaron Zambrana,Lisa As Walker et al.
Viral P Patel et al.
The present study assesses the influence of depression and anxiety on the effects of cognitive distracters in people with multiple sclerosis (MS). Participants completed computerized versions of the Symbol Digit Modalities Test (c-SDMT) wit...
A case of presumed herpes keratouveitis in a patient treated with fingolimod [0.03%]
一名服用芬戈莫德的患者疑似患带状疱疹性角膜结膜炎病例报告
Malissa C Ayers,Devon S Conway
Malissa C Ayers
We discuss a case of presumed bilateral herpes simplex keratouveitis in a 36-year-old multiple sclerosis patient switched to fingolimod from glatiramer acetate. Fingolimod treatment appears to increase the risk of herpesvirus infections, in...
Evaluation of French-language internet sites dealing with multiple sclerosis [0.03%]
评估用法语发布有关多发性硬化的网站信息的质量
Antoine Guéguen,Elisabeth Maillart,Thibault Gallice et al.
Antoine Guéguen et al.
Background: Information available on the internet has changed patient-neurologist relationships. Its evaluation for multiple sclerosis is only partial, regardless of the language used. ...
Association of multiple sclerosis and sudden sensorineural hearing loss [0.03%]
多发性硬化症与突发性感音神经性听力损失的相关性
S Atula,S T Sinkkonen,R Saat et al.
S Atula et al.
Background: Multiple sclerosis (MS) may affect other cranial nerves besides the optic nerve. Sudden sensorineural hearing loss (SSHL), possibly caused by a deficit in the auditory tract, including the vestibulocochlear ne...
Erythrocytes in multiple sclerosis - forgotten contributors to the pathophysiology? [0.03%]
多发性硬化症中的红细胞——被遗忘的病理生理学贡献者吗？
Kira Groen,Vicki E Maltby,Katherine A Sanders et al.
Kira Groen et al.
Multiple sclerosis (MS) is an autoimmune disease characterised by lymphocytic infiltration of the central nervous system and subsequent destruction of myelin and axons. On the background of a genetic predisposition to autoimmunity, environm...
Burden of genetic risk variants in multiple sclerosis families in the Netherlands [0.03%]
荷兰多发性硬化家系的遗传风险变异负担
Julia Y Mescheriakova,Linda Broer,Simin Wahedi et al.
Julia Y Mescheriakova et al.
Background: Approximately 20% of multiple sclerosis patients have a family history of multiple sclerosis. Studies of multiple sclerosis aggregation in families are inconclusive. ...
The Neurological Sleep Index: A suite of new sleep scales for multiple sclerosis [0.03%]
神经睡眠指数：一套新的多发性硬化症睡眠量表
R J Mills,A Tennant,C A Young
R J Mills
Objective: The objective of this study was to develop patient-reported outcome measures for sleep dysfunction and sleepiness in multiple sclerosis (MS), since there are currently no MS-specific measurement tools for these...