A group-delivered self-management program reduces spasticity in people with multiple sclerosis: A randomized, controlled pilot trial [0.03%]
群组递送的自我管理程序可减少多发性硬化患者的痉挛症状:一项随机对照试点试验
Cinda L Hugos,Dennis Bourdette,Yiyi Chen et al.
Cinda L Hugos et al.
Background: Spasticity affects more than 80% of people with multiple sclerosis (MS), affecting activity, participation, and quality of life. Based on an international guideline, an MS spasticity group education and stretc...
Enhanced disease reduction using clozapine, an atypical antipsychotic agent, and glatiramer acetate combination therapy in experimental autoimmune encephalomyelitis [0.03%]
改良型抗精神病药氯丙嗪和醋酸格拉默联合治疗在自身免疫性脑脊髓炎实验研究中降低疾病活动度的效果增强
Laura K Green,Pirooz Zareie,Nikki Templeton et al.
Laura K Green et al.
Background: Atypical antipsychotic agents (AAP) alleviate the symptoms of severe mental health disorders, such as schizophrenia, by antagonizing dopamine and serotonin receptors. Recently, AAP have also been shown to exhi...
Assessment of treatment patterns associated with injectable disease-modifying therapy among relapsing-remitting multiple sclerosis patients [0.03%]
评估与注射型疾病修正疗法相关的治疗模式(复发缓解性多发性硬化症患者的研究)
J Nicholas,J J Ko,Y Park et al.
J Nicholas et al.
Background: Availability of oral disease-modifying therapy (DMT) for relapsing-remitting multiple sclerosis (RRMS) may affect injectable DMT (iDMT) treatment patterns. ...
Noninvasive tongue stimulation combined with intensive cognitive and physical rehabilitation induces neuroplastic changes in patients with multiple sclerosis: A multimodal neuroimaging study [0.03%]
无创舌刺激结合密集型认知和物理康复可诱导多发性硬化患者的神经可塑性变化:一项多模态神经影像学研究
Gabriel Leonard,Yves Lapierre,Jen-Kai Chen et al.
Gabriel Leonard et al.
Background: Multiple sclerosis (MS) patients have central nervous system (CNS) lesions that may impede cognitive and sensorimotor function. Few rehabilitative therapies are available. ...
An essential role of virus-infected B cells in the marmoset experimental autoimmune encephalomyelitis model [0.03%]
感染病毒的B细胞在狨猴自身免疫性脑脊髓炎实验模型中发挥重要作用
Bert A t Hart,Yolanda S Kap
Bert A t Hart
Infection with Epstein-Barr virus (EBV) has been associated with an enhanced risk of genetically susceptible individuals to develop multiple sclerosis (MS). However, an explanation for the contrast between the high EBV infection prevalence ...
Migraine and frequent tension-type headache are not associated with multiple sclerosis in a Norwegian case-control study [0.03%]
在一项挪威病例对照研究中,偏头痛和频繁紧张型头痛与多发性硬化症无关
M W Gustavsen,E G Celius,B S Winsvold et al.
M W Gustavsen et al.
Background: Inconsistent results have been obtained with regard to headache comorbidity in multiple sclerosis (MS). Objective: Investig...
The relationship between fatigability and sleep quality in people with multiple sclerosis [0.03%]
多发性硬化患者疲劳与睡眠质量的关系
Mayis Aldughmi,Jessie Huisinga,Sharon G Lynch et al.
Mayis Aldughmi et al.
Background: Perceived fatigue and fatigability are constructs of multiple sclerosis (MS)-related fatigue. Sleep disturbances lead to poor sleep quality, which has been found to be associated with perceived fatigue in peop...
Randomized controlled trial of exercise interventions to improve sleep quality and daytime sleepiness in individuals with multiple sclerosis: A pilot study [0.03%]
多发性硬化症患者的运动干预改善睡眠质量及日间嗜睡的随机对照试验——一项试点研究
Catherine F Siengsukon,Mayis Aldughmi,Melike Kahya et al.
Catherine F Siengsukon et al.
Background: Nearly 70% of individuals with multiple sclerosis (MS) experience sleep disturbances. Increasing physical activity in people with MS has been shown to produce a moderate improvement in sleep quality, and exerc...
Coping strategies in relation to negative work events and accommodations in employed multiple sclerosis patients [0.03%]
与消极工作事件和就业多发性硬化症患者有关的应对策略及适应能力
K van der Hiele,Dam van Gorp,Rhb Benedict et al.
K van der Hiele et al.
Background: Job loss is common in multiple sclerosis (MS) and is known to exert a negative effect on quality of life. The process leading up to job loss typically includes negative work events, productivity losses and a n...
Mary Ann Harp,Kevin K McCully,Marina Moldavskiy et al.
Mary Ann Harp et al.
Background: People with multiple sclerosis (MS) have functional disability and may have reduced muscle mitochondrial capacity. Objective: ...