Improved cognitive performance and event-related potential changes following working memory training in patients with multiple sclerosis [0.03%]
多发性硬化患者工作记忆训练后的认知表现及事件相关电位的改善
Thomas J Covey,Janet L Shucard,Ralph Hb Benedict et al.
Thomas J Covey et al.
Background: Few studies of cognitive rehabilitation in multiple sclerosis (MS) have targeted working memory specifically. Objective: We...
A double-blind, placebo-controlled, single ascending-dose study of remyelinating antibody rHIgM22 in people with multiple sclerosis [0.03%]
多发性硬化症患者单次递增剂量、双盲安慰剂对照的rHIgM22脱髓鞘再生成抗体研究
Andrew Eisen,Benjamin M Greenberg,James D Bowen et al.
Andrew Eisen et al.
Objective: The objective of this paper is to assess, in individuals with clinically stable multiple sclerosis (MS), the safety, tolerability, pharmacokinetics (PK) and exploratory pharmacodynamics of the monoclonal recomb...
Validation of the Brief International Cognitive Assessment for Multiple Sclerosis in Japan [0.03%]
日本多发性硬化国际简明认知评估的验证研究
Masaaki Niino,Toshiyuki Fukazawa,Jun-Ichi Kira et al.
Masaaki Niino et al.
Background: The Brief International Cognitive Assessment for MS (BICAMS) is a practical battery for measuring cognitive function in multiple sclerosis (MS). ...
Environmental temperature and exercise modality independently impact central and muscle fatigue among people with multiple sclerosis [0.03%]
环境温度和运动类型独立影响多发性硬化患者的中枢疲劳和肌肉疲劳
Geetika Grover,Michelle Ploughman,Devin T Philpott et al.
Geetika Grover et al.
Background: Heat sensitivity and fatigue limit the ability of multiple sclerosis patients to participate in exercise. Objective: The pu...
Thrombin generation correlates with disease duration in multiple sclerosis (MS): Novel insights into the MS-associated prothrombotic state [0.03%]
血栓调节蛋白的生成与多发性硬化病程相关：关于多发性硬化相关促凝状态的新观点
Martin Em Parsons,Karen O&#x;Connell,Seamus Allen et al.
Martin Em Parsons et al.
Background: Thrombin is well recognised for its role in the coagulation cascade but it also plays a role in inflammation, with enhanced thrombin generation observed in several inflammatory disorders. Although patients wit...
Interferon beta-1b in treatment-naïve paediatric patients with relapsing-remitting multiple sclerosis: Two-year results from the BETAPAEDIC study [0.03%]
β干扰素-β-1b在小儿复发型多发性硬化症初治患者中的疗效：BETAPAEDIC研究的两年结果
Jutta Gärtner,Wolfgang Brück,Almuth Weddige et al.
Jutta Gärtner et al.
Background and objective: Study evaluating Betaferon(R)'s safety and tolerability in paediatric patients with multiple sclerosis (BETAPAEDIC) is a prospective, open-label observational multicentre study to assess the safe...
Subcutaneous interferon β-1a three times weekly and the natural evolution of gadolinium-enhancing lesions into chronic black holes in relapsing and progressive multiple sclerosis: Analysis of PRISMS and SPECTRIMS trials [0.03%]
重组干扰素β-1a皮下注射每周三次与复发型多发性硬化症及进行性多发性硬化症患者中钆增强病灶的自然演变成为慢性黑灶：PRISMS和SPECTRIMS试验分析
A Traboulsee,Dkb Li,R Tam et al.
A Traboulsee et al.
Background: Evolution of gadolinium-enhancing lesions into chronic black holes (CBH) may be reduced by interferon (IFN) therapy. Objective: ...
Randomized, Placebo-controlled Crossover Study of Dalfampridine Extended-release in Transverse Myelitis [0.03%]
延髓炎患者使用盐酸达氟米idine缓释片的随机双盲对照交叉研究
Kateryna Schwartz,Nicholas F Wymbs,Hwa Huang et al.
Kateryna Schwartz et al.
Background: Dalfampridine has the potential to be effective in patients with transverse myelitis (TM) as this rare disorder shares some clinical and pathogenic similarities with multiple sclerosis. ...
Serum Neurofilament Light Chain in NMOSD and Related Disorders: Comparison According to Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein Antibodies Status [0.03%]
NMOSD及相关疾病血清神经丝轻链根据AQP4和MOG抗体状态的比较
Mariotto S,Farinazzo A,Monaco S et al.
Mariotto S et al.
Background: Neurofilament light chain (NF-L) levels reflect axonal damage in different conditions, including demyelinating disorders. Objectives: ...
Antibody response against HERV-W env surface peptides differentiates multiple sclerosis and neuromyelitis optica spectrum disorder [0.03%]
针对HERV-W_env表面肽的抗体反应可区分多发性硬化和视神经脊髓炎谱系疾病
Giannina Arru,Elia Sechi,Sara Mariotto et al.
Giannina Arru et al.
Background: A specific humoral immune response against HERV-W envelope surface (env-su) glycoprotein antigens has been reported in serum of patients with multiple sclerosis (MS). However, it has not been evaluated to date...