Feasibility of mesenchymal stem cell culture expansion for a phase I clinical trial in multiple sclerosis [0.03%]
多发性硬化症I期临床试验的间充质干细胞培养扩增的可行性研究
Sarah M Planchon,Karen T Lingas,Jane Reese Koç et al.
Sarah M Planchon et al.
Background: Multiple sclerosis is an inflammatory, neurodegenerative disease of the central nervous system for which therapeutic mesenchymal stem cell transplantation is under study. Published experience of culture-expand...
No evidence of disease activity (NEDA) analysis by epochs in patients with relapsing multiple sclerosis treated with ocrelizumab vs interferon beta-1a [0.03%]
奥扎莫德与干扰素β-1a治疗复发性多发性硬化症患者的无疾病活动证据(NEDA)分析:一项依期分析结果
Eva Havrdová,Douglas L Arnold,Amit Bar-Or et al.
Eva Havrdová et al.
Background: No evidence of disease activity (NEDA; defined as no 12-week confirmed disability progression, no protocol-defined relapses, no new/enlarging T2 lesions and no T1 gadolinium-enhancing lesions) using a fixed-st...
Prolonged-Release Fampridine as Adjunct Therapy to Active Motor Training in MS Patients: A Pilot, Double-Blind, Randomized, Placebo-Controlled Study [0.03%]
延长释放型富马酸氟吡汀作为MS患者的辅助治疗以积极进行运动训练:一项初步的双盲随机安慰剂对照研究
François Jacques,Adrian Schembri,Avi Nativ et al.
François Jacques et al.
Background: Both prolonged-release fampridine (PRF) and enabling active motor training (EAMT) are beneficial in multiple sclerosis (MS) patients. Their combined effect is, however, understudied. ...
Severe aquaporin 4-IgG-positive neuromyelitis optica with disseminated herpes zoster in a pregnant woman successfully treated with intravenous immunoglobulin [0.03%]
重症抗水通道蛋白-4抗体阳性视神经脊髓炎合并带状疱疹成功应用静脉注射免疫球蛋白治疗一例孕妇病人报告
Yuki Matsumoto,Mario Tsuchiya,Shakespear Norshalena et al.
Yuki Matsumoto et al.
A 26-year-old, 17-week pregnant woman developed aquaporin-4-IgG-positive severe longitudinally extensive transverse myelitis during the course of disseminated herpes zoster and became quadriparetic. She was unresponsive to high-dose intrave...
Treadmill walking exercise training and brain function in multiple sclerosis: Preliminary evidence setting the stage for a network-based approach to rehabilitation [0.03%]
跑步运动训练和脑功能在多发性硬化症中的作用:基于网络的康复方法的初步证据
Brian M Sandroff,Glenn R Wylie,Brad P Sutton et al.
Brian M Sandroff et al.
Exercise training has been identified as a highly promising approach for managing the cognitive consequences of multiple sclerosis (MS). This study represents a secondary analysis of resting-state functional connectivity (RSFC) magnetic res...
Risk factors for fingolimod-induced lymphopenia in multiple sclerosis [0.03%]
富马酸二甲酯致多发性硬化患者淋巴细胞减少的风险因素分析
Ryohei Ohtani,Masahiro Mori,Tomohiko Uchida et al.
Ryohei Ohtani et al.
Background: Lymphopenia is a well-known adverse event of fingolimod, a disease-modifying drug for multiple sclerosis (MS). Objectives: ...
A randomized study to evaluate the effect of exercise on fatigue in people with relapsing-remitting multiple sclerosis treated with fingolimod [0.03%]
评价富马酸二甲酯治疗复发性多发性硬化症患者的疲劳感的随机研究
M Mäurer,K Schuh,S Seibert et al.
M Mäurer et al.
Background: Fatigue is a major symptom of multiple sclerosis (MS) in patients, and it has been shown to improve with physical exercise. Although fingolimod might lessen fatigue, it is unclear how patients treated with fin...
Movement measurements at home for multiple sclerosis: walking speed measured by a novel ambient measurement system [0.03%]
多发性硬化症家庭活动度测量:通过新型环境测量系统测定步行速度
Victoria Mj Smith,Jonathan S Varsanik,Rachel A Walker et al.
Victoria Mj Smith et al.
Background: Gait disturbance is a major contributor to clinical disability in multiple sclerosis (MS). A sensor was developed to assess walking speed at home for people with MS using infrared technology in real-time witho...
National estimates of self-reported sitting time in adults with multiple sclerosis [0.03%]
多发性硬化症成人患者中全国范围的久坐行为流行情况估计
J E Sasaki,R W Motl,G Cutter et al.
J E Sasaki et al.
Background: Limited data exist on the prevalence and distribution of sedentary behavior (SB) in multiple sclerosis (MS). Objective: The...
Diagnosis and treatment of latent tuberculosis in patients with multiple sclerosis, expert consensus. On behalf of the Colombian Association of Neurology, Committee of Multiple Sclerosis [0.03%]
哥伦比亚神经病学协会多发性硬化症委员会关于多发性硬化患者潜伏结核感染的诊断与治疗共识
Carlos Navas,Carlos A Torres-Duque,Joe Munoz-Ceron et al.
Carlos Navas et al.
Background: Multiple sclerosis is an inflammatory and neurodegenerative demyelinating disease. Current treatment of multiple sclerosis focuses on the use of immunomodulatory, immunosuppressant, and selective immunosuppres...