Epidemiology of neuromyelitis optica spectrum disease in Central-West Brazil: Prevalence and associated clinical and demographic features [0.03%]
巴西中西部视神经脊髓炎谱系疾病的流行病学:患病率及相关的临床和人口统计学特征
Nícolas Philippe Balduino Nogueira,Rodolfo Rego Deusdara Rodrigues,Tainá Barreto Cavalcante et al.
Nícolas Philippe Balduino Nogueira et al.
Background: Neuromyelitis optica spectrum diseases (NMOSD) are rare autoimmune diseases of the central nervous system. Although Brazil reports one of the highest global prevalences of NMOSD, regional data, particularly fr...
Factors associated with delays in multiple sclerosis disease-modifying therapy initiation [0.03%]
影响多发性硬化症疾病修正治疗启动延迟的因素分析
Laura Snider,Elsa Rodriguez,Hannah Rains et al.
Laura Snider et al.
Background: In multiple sclerosis (MS), delays in initiation of disease-modifying therapy (DMT) are associated with worse clinical outcomes. Methods: ...
Percutaneous spinal stimulation to enhance gait and alleviate functional impairments in multiple sclerosis: A pilot study [0.03%]
经皮脊髓电刺激改善多发性硬化患者步态及功能障碍的可行性研究:一项试点试验
Omid Jahanian,Anders J Asp,Megan L Gill et al.
Omid Jahanian et al.
Objective: To evaluate the feasibility and potential efficacy of percutaneous spinal stimulation (epidural stimulation, ES) combined with task-specific training to reduce spasticity and improve gait and balance in individ...
Status for and associations between disability, employment, barriers for work and health-related quality of life in individuals with multiple sclerosis: A cross-sectional study [0.03%]
多发性硬化症患者的残疾、就业、工作障碍和健康相关生活质量之间的状况及关联:一项横断面研究
E C Arntzen,H K Fikke,M Sivertsen et al.
E C Arntzen et al.
Background: People with multiple sclerosis (pwMS) often face complex challenges leading to work-related barriers, reduced employment and impaired health-related quality of life (HRQOL). ...
Comparative analysis of lung function in supine and sitting positions in patients with moderate multiple sclerosis [0.03%]
中度多发性硬化患者仰卧位和坐位肺功能比较分析
Joar Wikars,Margareta Kånåhols,Ylva Nilsagård et al.
Joar Wikars et al.
Background: Multiple sclerosis (MS) is a progressive disease that may affect respiratory muscle function. Pulmonary dysfunction may be subclinical, and posture changes can reduce lung volumes, especially in the presence o...
Closing the referral gap: The role of a quality improvement initiative to enhance pelvic health physical therapy referrals for persons with multiple sclerosis-related bladder symptoms [0.03%]
弥合转诊差距:提高多发性硬化症相关膀胱症状患者盆底物理治疗转诊率的质量改进举措的作用
Ilana Winawer,Riley Bove,Jaeleene Wijangco et al.
Ilana Winawer et al.
Background: Multiple sclerosis (MS)-related bladder dysfunction (BD) affects up to 80% of people with MS (PwMS) and substantially impacts mobility, safety, and quality of life. Pelvic Health Physical Therapy (PHPT) is an ...
Large language models as clinical decision-support tools in multiple sclerosis and neuromyelitis optica spectrum disorders: A comparative study of ChatGPT-4o and neurologists [0.03%]
大型语言模型作为多发性硬化和视神经脊髓炎谱系疾病临床决策支持工具的比较研究:ChatGPT-4o与神经科医生的对比
Gustavo Saposnik,Aleix Solanes,Enric Monreal et al.
Gustavo Saposnik et al.
Background: Therapeutic inertia (TI) remains a critical barrier to optimizing outcomes in multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSDs). ...
Tumefactive demyelination in older adults: A scoping review of published cases [0.03%]
老年人肿瘤样脱髓鞘病变的发表病例综述
Carla De Pasquale,Todd A Hardy
Carla De Pasquale
Tumefactive demyelinating lesions (TDLs) are rare in older populations. In this scoping review we conducted a PUBMED search for published cases of TDLs in patients aged ≥55 years. We identified 31 cases and report data on their presentatio...
Measurement of functional mobility in multiple sclerosis: A crosswalk between the patient-determined disease steps and the Neuro-QoL Lower Extremity Function-Short Form [0.03%]
多发性硬化患者下肢功能的测评:Patient-Determined Disease Steps与Neuro-QoL下肢功能简表之间的互换性研究
Alexa S Gonzalez,Joshua M Garcia,Eric Engebretson et al.
Alexa S Gonzalez et al.
Background: The Patient-Determined Disease Steps (PDDS) and Neuro-QoL Lower Extremity Function-Short Form (Neuro-QoL LEF-SF) are patient-reported outcome measures used to monitor mobility symptoms in multiple sclerosis (M...
Assessment of the impact of outcome definitions on power in multiple sclerosis clinical trials [0.03%]
结局定义对多发性硬化临床试验效能影响的评估
Cynthia X Li,Bonnie I Glanz,Moogeh Baharnoori et al.
Cynthia X Li et al.
Background: Clinical trials for disease progression in multiple sclerosis (MS) often use a confirmed increase on the expanded disability status scale (EDSS) as the primary outcome. ...