Workplace difficulties in early-stage relapsing-remitting multiple sclerosis with low physical disability [0.03%]
轻度身体残疾的早期复发性多发性硬化症患者的工作困难
Ángel Pérez-Sempere,Elena García-Arcelay,Jacobo Caruncho et al.
Ángel Pérez-Sempere et al.
This study evaluated perceived workplace difficulties in 128 individuals with early-stage relapsing-remitting multiple sclerosis and low physical disability. Significant workplace challenges were reported by 40.6% of participants. External ...
Validation of an alternative algorithm to oligoclonal bands. Free Light Chains in Cerebrospinal Fluid: Quantitative and Qualitative method [0.03%]
用于脑脊液的轻链检测：寡克隆带替代算法的验证定量和定性方法
María Laura Facio,Marcelo Garcia,Benjamín Baraκian et al.
María Laura Facio et al.
Background: Nearly 85% of patients with Multiple Sclerosis (MS) present oligoclonal bands (OB) by isoelectric focusing (IEF) in their cerebrospinal fluid (CSF). Currently, it is proposed to quantify free light chains (FLC...
Myelin damage in radiologically isolated syndrome is associated with decreased processing speed [0.03%]
放射性孤立综合征患者的髓鞘损害与处理速度下降相关
Olivia Kalau,Poljanka Johnson,Jiwon Oh et al.
Olivia Kalau et al.
Background: Cognitive impairment (CI) is a common feature of multiple sclerosis (MS). Radiologically isolated syndrome (RIS) can demonstrate CI patterns similar to MS, providing an opportunity to explore the associations ...
Reinitiating ocrelizumab with a full 600 mg dose after extended treatment interruption: No increased risk of infusion-related reactions [0.03%]
奥瑞珠单抗长时间治疗中断后恢复使用常规600毫克剂量：没有增加的输注相关反应风险
Lisa G Schoof,Laura Hogenboom,Zoé LE van Kempen et al.
Lisa G Schoof et al.
Background: Infusion-related reactions (IRRs) are a common side-effect of ocrelizumab (OCR), with the highest risk occurring during treatment initiation. To minimize IRR risk, the first dose is split into two 300 mg infus...
Discrepancy between subjective and objective cognitive function in multiple sclerosis and association with mood, fatigue, and pain [0.03%]
多发性硬化症主观认知功能和客观认知功能不符以及与情绪、疲劳和疼痛的关系
Nour Farah,Simon Charbonneau,Sarah A Morrow et al.
Nour Farah et al.
Background: Interpretation of cognitive impairment (CI) in persons with multiple sclerosis (PwMS) is limited by discrepancies between objective and subjective evaluation. ...
Neuromyelitis optica spectrum disorder in Germany: A claims data analysis of incidence, prevalence, treatment patterns, and diagnostic overlap with multiple sclerosis [0.03%]
德国视神经脊髓炎谱系疾病的真实世界研究：基于保险数据的发病率、患病率、治疗模式和与多发性硬化的诊断重叠情况分析
Matthias Grothe,Katja Nettermann,Ursula Marschall et al.
Matthias Grothe et al.
Background: Neuromyelitis optica spectrum disorders (NMOSD) are rare autoimmune diseases of the central nervous system. Global prevalence estimates vary widely, and data for Germany are limited. ...
Amber Salter,Mudita Sharma,Gary R Cutter et al.
Amber Salter et al.
Background: Men with multiple sclerosis (MwMS) experience distinct health, symptoms, and disease progression patterns compared to women, necessitating targeted research and clinical approaches. ...
Long-term follow-up of patients with multiple sclerosis over age 60: Comparing clinical and radiological outcomes in disease-modifying therapy continuers and discontinuers [0.03%]
大于60岁的多发性硬化症患者的长期随访：疾病修正疗法的继续使用者和停止使用者的临床及影像学结果比较
Daniel R Orme,Eric Matesen,Devon Conway et al.
Daniel R Orme et al.
Background: Relapse prevention in multiple sclerosis (MS) is accomplished with disease-modifying therapy (DMT). Relapse rates typically decrease with age while DMT-associated risks increase, complicating treatment of olde...
Eye movement analysis during working memory tasks correlates with cognitive, clinical, and anatomical metrics in multiple sclerosis [0.03%]
眼动追踪技术在多发性硬化症工作记忆任务中的应用及其与认知、临床和解剖测量的关系研究
Cecilie Fjeldstad Pardo,Gerardo Fernandez,Bujana Allushi et al.
Cecilie Fjeldstad Pardo et al.
Background: Cognitive dysfunction involving working memory is common in multiple sclerosis (MS) but is often under-detected in clinical assessments. Noninvasive digital biomarkers like oculomotor metrics may enhance the d...
Feasibility and preliminary outcomes of a remotely-delivered exercise training intervention for English-speaking Hispanics/Latinos with multiple sclerosis: Results from the FERLA MS study [0.03%]
英语 speaking西班牙裔/拉丁美洲多发性硬化症患者的远程锻炼干预的可行性和初步结果：来自FERLA MS研究的结果
Victoria A Flores,Stephanie L Silveira,David X Marquez et al.
Victoria A Flores et al.
Background: There is limited evidence on the feasibility of remotely delivered exercise interventions for English-speaking Hispanics/Latinos with MS. Obje...