Allele-specific vitamin D receptor binding is associated with pediatric-onset multiple sclerosis [0.03%]
维生素D受体结合的等位基因特异性与儿童期发病的多发性硬化症相关
Defne Yilmaz,Cameron Adams,Mary K Horton et al.
Defne Yilmaz et al.
Background and objectives: The genetic basis of adult-onset multiple sclerosis (MS) is well-studied, but less is known about pediatric-onset MS (pedMS), comprising approximately 5% of all MS onsets. Mendelian randomizatio...
Test-retest reliability of Cirrus HD-optical coherence tomography retinal layer thickness measurements in people with multiple sclerosis [0.03%]
检测多发性硬化患者的Cirrus HD光学相干断层扫描视网膜各层厚度的重复测量一致性
Anna Bacchetti,Brenna McCormack,Ting-Yi Lin et al.
Anna Bacchetti et al.
Background: Optical coherence tomography (OCT) allows evaluation of inter-eye differences (IEDs) in peri-papillary retinal nerve fiber layer (pRNFL) and macular ganglion cell-inner plexiform layer (GCIPL) thicknesses to i...
Race- and place-based disparities in multiple sclerosis care: A qualitative study of patient experiences [0.03%]
基于种族和地理位置的多发性硬化症护理差异：患者体验的定性研究
Kavya Bhattiprolu,Brett L Opelt,Miranda R Jones et al.
Kavya Bhattiprolu et al.
Background: Multiple sclerosis is a neurodegenerative and neuroinflammatory disease causing a variety of symptoms, involving physical and cognitive domains. Previous research has demonstrated that racial disparities are p...
Diagnostic delay and misdiagnosis of symptoms reported by patients with multiple sclerosis participating in a research registry [0.03%]
多重硬化症患者的诊断延迟和误诊：来自研究注册中心的数据报告症状
Andrew J Solomon,Sarah M Weinstein,Russell T Shinohara et al.
Andrew J Solomon et al.
Background: Research cohort data suggest diagnostic delay in multiple sclerosis (MS) has diminished in tandem with MS diagnostic criteria revisions, yet other studies have not replicated this finding. Recent data indicate...
Real-world clinical utility of a multi-protein, blood-based biomarker assay for disease activity assessments in multiple sclerosis [0.03%]
一种多蛋白血液生物标志物检测在多发性硬化病活动度评估中的真实世界临床效用
Angela Sanchez,Elisa Sheng,Sarah Eagleman et al.
Angela Sanchez et al.
Background: Blood-based biomarkers have emerged as promising tools to optimize treatment decisions in multiple sclerosis (MS) including initiation, switch, or cessation of disease modifying therapies. ...
Ellagic acid favorable effects on fatigue, depression and anxiety in patients with multiple sclerosis and moderate disability: A randomized clinical trial [0.03%]
ellagic酸对中度残疾多发性硬化症患者的疲劳、抑郁和焦虑的有利影响：一项随机临床试验
Sahar Jafari Karegar,Abasat Mirzaei,Ghazaleh Hajiluian et al.
Sahar Jafari Karegar et al.
Background: This study aimed to evaluate the impact of ellagic acid (EA) on fatigue, depression, and anxiety in patients with multiple sclerosis (MS) who have moderate disability. ...
Plasma Exchange vs. Immunoadsorption: Effects on Immunological Markers and Predictive Value in Steroid-Refractory MS Attacks [0.03%]
血浆置换与免疫吸附：对难治性MS急性发作的免疫标记物影响及预后价值的比较研究
Ioannis Vardakas,Johannes Dorst,André Huss et al.
Ioannis Vardakas et al.
Background: Evidence on neurochemical mechanisms underlying response to apheresis in steroid-refractory Multiple Sclerosis (MS) attacks is limited. Object...
Enhancing everyday memory and participation in multiple sclerosis: A pilot study of a metacognitive strategy-based intervention [0.03%]
一项关于 MS 患者的元认知策略干预法的试点研究：改善日常生活记忆和参与度
Yael Goverover,Meirav Rosenfeld,John DeLuca et al.
Yael Goverover et al.
Background: Cognitive dysfunction in individuals with multiple sclerosis (MS) is associated with limitations in daily activities and restricted participation. Existing interventions for cognitive dysfunction often show in...
Assessing fall risk in multiple sclerosis using patient-reported outcomes and wearable gait metrics [0.03%]
基于患者报告的结果和穿戴式步态指标评估多发性硬化患者的跌倒风险
Samantha A Banks,Charles L Howe,Jay Mandrekar et al.
Samantha A Banks et al.
Background: Falls in people with multiple sclerosis (pwMS) lead to morbidity and expense. Objective: Identify clinical metrics associat...
Evaluating patient care in multiple sclerosis: Impact of combined digital tools and holistic management strategies [0.03%]
多发性硬化患者护理的评估：综合数字工具和全面管理策略的影响
Agne Straukiene,Sarah Hughes,Jon Grundy et al.
Agne Straukiene et al.
Background: Innovations are essential to meet the needs of people with MS (PwMS), particularly in addressing delays in diagnosis and treatment, and in supporting patient self-management. ...