Disproportionality analysis of adverse events in advanced lung cancer treated with atezolizumab plus platinum-based combination chemotherapy [0.03%]
阿特朱单抗联合含铂化疗治疗晚期肺癌不良反应的不对性分析
Katsuyuki Hazama,Toru Imai,Naohiro Tochikura et al.
Katsuyuki Hazama et al.
Background: Advanced non-squamous non-small cell lung cancer has a poor prognosis, and immune checkpoint inhibitors (ICIs) plus platinum-based combination chemotherapy is the first-line treatment. Atezolizumab, an ICI, ha...
Postoperative D-dimer as a signal of venous thromboembolism in patients receiving Edoxaban after hip or knee arthroplasty [0.03%]
接受艾多沙班治疗的人群在髋关节或膝关节置换术后出现术后D-二聚体信号作为静脉血栓栓塞的标志
Norito Nishiyama,Shiori Iwane,Masayuki Tanaka et al.
Norito Nishiyama et al.
Background: Edoxaban is the only direct-acting oral anticoagulant (DOAC) indicated for preventing venous thromboembolism (VTE) in patients undergoing arthroplasty and can be administered for a short period (1-2 weeks). Th...
Baseline serum albumin level as a predictive factor for the efficacy of trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer: a retrospective cohort study [0.03%]
基线白蛋白水平作为转移性结直肠癌三氟尿苷/tipiracil联合贝伐珠单抗疗效的预测因素：一项回顾性队列研究
Masatoshi Maki,Ryo Takada,Haruka Sumii et al.
Masatoshi Maki et al.
Frequency, patient characteristics, and clinical management for extravasation with docetaxel: a descriptive study using a large Japanese medical claims database [0.03%]
日本大型医保数据库描述性研究：多西他赛外渗发生率、患者特征及临床处理方式
Rina Yanagisawa,Ryo Inose,Yuichi Muraki
Rina Yanagisawa
Background: Extravasation (EV) as an adverse effect of chemotherapy can induce tissue damage. Japanese guidelines on EV associated with cancer drug therapy were published in December 2022. However, few large-scale investi...
Pharmacist follow-up of patients prescribed nirmatrelvir/ritonavir: a single-center retrospective analysis [0.03%]
尼马曲韦/利托那韦处方患者的药学随访：单中心回顾性分析
Ayako Shigeno,Yasukata Ohashi,Ryosuke Masui et al.
Ayako Shigeno et al.
Background: Nirmatrelvir/ritonavir (NMV/r), a drug used to treat coronavirus disease 2019, has raised concerns about potential drug-drug interactions with concomitant medications due to cytochrome P450 3 A inhibition. How...
Five-year follow-up with the incidence of cardiovascular adverse events after prescribing single-pill combination of antihypertensive drugs: retrospective cohort study [0.03%]
单片复方降压药处方后心血管不良事件发生率的5年随访：回顾性队列研究
Misa Matsumura,Toshiaki Nakamura,Kaori Kadoyama et al.
Misa Matsumura et al.
Background: This study aimed to investigate whether medication adherence was changed by the prescription of a single-pill combination (SPC) of antihypertensive drugs and whether it was associated with the incidence of maj...
Anemia in heart failure: evidence from a three-year cross-sectional study in Sudan [0.03%]
苏丹三年横断面研究揭示的心力衰竭相关贫血证据
Maram M Elamin,Rayan Hafiz Mohamed,Mohamed Alzaki Ahmed et al.
Maram M Elamin et al.
Background: Anemia is a frequent complication of heart failure (HF) that exacerbates cardiac dysfunction and worsens prognosis. However, its exact burden and treatment patterns in Sudan HF remain unknown. Thus, this study...
A cross-sectional survey of knowledge regarding sodium-glucose co-transporter 2 inhibitors (SGLT2is) among primary care physicians and pharmacists in China [0.03%]
中国基层医师和药师对钠葡萄糖共转运体2抑制剂认知的横断面调查研究
Yu Dong,Shunfu Zheng,Wenjing Wang et al.
Yu Dong et al.
Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2is) occupy a pivotal role in the management of Type 2 diabetes due to their unique glucose-lowering mechanism and multiple clinical benefits. Physicians, as deci...
Identification of potentially inappropriate medications characteristic of older individuals with diabetes: a study using pharmacy claims data [0.03%]
基于药房医保数据的糖尿病老年患者潜在不适宜药物清单研究
Takashi Yamamoto,Yoshihito Kasanami,Tomoyoshi Miyamoto et al.
Takashi Yamamoto et al.
Background: Older patients with diabetes often require multiple medications to manage complications, and have a high risk of potentially inappropriate medications (PIMs). Given limited information regarding diabetes-speci...
Usefulness of protocol-based pharmacotherapy management by pharmacists in cancer patients: a retrospective observational study [0.03%]
基于协议的药学管理在癌症患者中的应用价值：回顾性观察研究
Satomi Sumikawa,Noriaki Hidaka,Yuya Sakamoto et al.
Satomi Sumikawa et al.
Background: A team-based approach is essential to provide cancer patients with high-quality treatment. To ensure the best possible care while reducing the workload of physicians, Ehime University Hospital has introduced t...