Serum KL-6 and eGFR predict everolimus-associated KL-6 elevation in heart transplant recipients: a retrospective observational study [0.03%]
血清KL-6和eGFR可预测他克莫司相关的心脏移植受者的KL-6升高：一项回顾性观察研究
Yuhei Suzuki,Toyohito Oriyama,Takehito Yamamoto et al.
Yuhei Suzuki et al.
Background: Everolimus (EVR), which is widely used in heart transplant recipients, has been associated with drug-induced lung injury. Although EVR-associated lung injury has been reported in patients with malignancies and...
Risk modifiers of immune-related adverse events in patients with NSCLC undergoing immunotherapy: a retrospective cohort study [0.03%]
免疫治疗过程中影响非小细胞肺癌患者发生免疫相关不良事件的风险因素：一项回顾性队列研究
Takashi Watanabe,Naoto Suzuki,Masahito Yamauchi et al.
Takashi Watanabe et al.
Background: To investigate immune-related adverse events (irAEs) in patients with non-small cell lung cancer receiving immune checkpoint inhibitor (ICI) therapy, and to identify clinical factors associated with irAE onset...
VEGF inhibitor-induced proteinuria: the role of hypertension and vascular endothelial dysfunction [0.03%]
血管紧张素的作用及血管内皮功能障碍诱导的蛋白尿作用机制研究
Satoru Nihei,Kazuki Saito,Kenzo Kudo
Satoru Nihei
Vascular endothelial growth factor (VEGF) inhibitors are widely used anticancer agents that suppress tumor angiogenesis and improve outcomes in various solid tumors. However, these therapies are frequently associated with adverse renal and ...
Impact of community pharmacists on improving polypharmacy in elderly outpatients: a community-based intervention study [0.03%]
基于社区的药房干预改善老年人门诊多重用药问题的研究
Takahiro Furuta,Kazuyoshi Fujitani,Eriko Minami et al.
Takahiro Furuta et al.
Background: Polypharmacy, defined as the inappropriate use of multiple concomitant medications, represents a major concern in elderly care and is associated with drug-drug interactions, adverse effects, and poor medicatio...
Empowering community pharmacists: expert consensus guidance for the effective management of peripheral neuropathy with neurotropic B vitamins [0.03%]
增强社区药房药师的能力：关于使用神经营养B族维生素有效管理外周神经病变的专家共识指导意见
Yolanda R Robles,Lusy Noviani,Kitiyot Yotsombut et al.
Yolanda R Robles et al.
Introduction: Peripheral neuropathy (PN) is a prevalent condition in the Asia-Pacific region with a significant proportion of undiagnosed cases. Despite heterogeneous pharmacy practices across the region, clinical and ope...
Exploring staffing and hospital factors associated with WardPharm-1 filing in Japan: a nationwide observational study [0.03%]
日本全国观察性研究：探索药房住院部门药师配置及相关医院因素的影响
Masayuki Kaneda,Maho Taguchi,Hiroaki Yamada et al.
Masayuki Kaneda et al.
Background: The healthcare system of Japan faces mounting challenges, including population aging, medical complexity, and workforce shortages. Hospital pharmacists are expected to ensure the safe and effective use of medi...
Association between voltage-gated sodium channel gene polymorphisms and chronic oxaliplatin-induced peripheral neuropathy in Japanese patients with colorectal cancer [0.03%]
电压门控钠通道基因多态性与日本结直肠癌患者慢性奥沙利铂诱导的外周神经病变之间的关系
Masato Matsuura,Ayumu Nagamine,Takashi Masuno et al.
Masato Matsuura et al.
Background: Polymorphisms in voltage-gated sodium channel (SCN) genes have been implicated in oxaliplatin-induced peripheral neuropathy (OXAIPN). However, their association with chronic OXAIPN in Japanese patients remains...
Changes in remimazolam plasma concentration associated with the Pringle maneuver during hepatectomy: a pilot study [0.03%]
普林格尔法治疗肝切除术中瑞马唑仑血药浓度变化的初步研究
Shunya Ogawa,Hirotsugu Kanda,Takahiro Ito et al.
Shunya Ogawa et al.
Background: Remimazolam (RMZ) is an ultrashort-acting benzodiazepine used in general anesthesia, metabolized rapidly by carboxylesterase 1, an enzyme primarily located in the liver. The Pringle maneuver (PM), an establish...
An evaluation of factors affecting the usefulness and sustainability of inter-pharmacist case conferences [0.03%]
影响药师病例会议实用性和可持续性的因素评估
Shun Tsujimura,Kanayuki Kitahara,Shin Tanaka et al.
Shun Tsujimura et al.
Background: Inter-pharmacist case conferences, in which practitioners routinely discuss drug therapy, are expected to improve the validity of clinical judgements and provide educational benefits. However, evidence regardi...
Prolongation of prothrombin time-international normalized ratio by concomitant use of warfarin and combination therapy with lenvatinib and pembrolizumab in a patient with renal cell carcinoma on dialysis: a case report [0.03%]
一例接受透析的肾细胞癌患者联用华法林和仑伐替尼联合帕博利珠单抗治疗导致凝血酶原时间-国际 normalized 比值延长的病例报告
Shota Torii,Tomoya Narita,Aya Torii-Goto et al.
Shota Torii et al.
Background: Acquired polycystic kidney disease is associated with an increased risk of developing renal cell carcinoma (RCC), which is commonly observed in patients on dialysis and may present with inferior vena cava tumo...