Cost-minimization analysis of adjuvant chemotherapy regimens given to patients with colorectal cancer in Japan [0.03%]
日本结直肠癌辅助化疗方案的成本最小化分析
Kosuke Takata,Ken-Ichi Fujita,Yutaro Kubota et al.
Kosuke Takata et al.
Background: Consideration of medical costs as well as effectiveness and adverse events is rapidly been becoming an important factor in the selection of chemotherapy regimens. However, practical data on the costs of chemot...
Possible involvement of distinct phylogenetic clusters of HIV-1 variants in the discrepancies between coreceptor tropism predictions based on viral RNA and proviral DNA [0.03%]
HIV-1不同谱系毒株与基于病毒RNA和宿主DNA的核心受体嗜性预测差异的可能关系
Hiroshi Kotani,Koji Sudo,Naoki Hasegawa et al.
Hiroshi Kotani et al.
Background: The coreceptor tropism testing should be conducted prior to commencing a regimen containing a CCR5 antagonist for treatment of HIV-1 infection. For aviremic patients on long antiretroviral therapy, proviral DN...
Pregabalin prescription for terminally ill cancer patients receiving specialist palliative care in an acute hospital [0.03%]
终末期癌症患者专科姑息治疗中普瑞巴林的处方使用情况研究
Ryo Yajima,Kazuaki Matsumoto,Yuya Ise et al.
Ryo Yajima et al.
Background: Pregabalin is recommended as an adjuvant analgesic for neuropathic cancer-related pain, and may be taken at all steps of the World Health Organization analgesic ladder. However, unlike opioids, pregabalin trea...
Effectiveness of activated carbon masks in preventing anticancer drug inhalation [0.03%]
活性炭口罩预防抗癌药物吸入的效果研究
Junya Sato,Atushi Kogure,Kenzo Kudo
Junya Sato
Background: The exposure of healthcare workers to anticancer drugs such as cyclophosphamide (CPA) is a serious health concern. Anticancer drug pollution may spread outside biological safety cabinets even when a closed sys...
Early rehospitalization after initial chronic kidney disease educational hospitalization relates with a multidisciplinary medical team [0.03%]
初始慢性肾脏病住院教育与多学科医疗团队有关影响再住院率
Eiji Kose,Taesong An,Akihiko Kikkawa et al.
Eiji Kose et al.
Background: It is well-documented that chronic kidney disease (CKD) often results in end-stage renal failure and puts patients at extremely high risk for developing cardiovascular disease. Educational hospitalization at m...
Application of ozone gas for decontamination of nucleoside anticancer drugs [0.03%]
臭氧气体脱除核苷类抗肿瘤药物污染的应用
Ayumi Tsukamoto,Shunji Ishiwata,Asami Kajimoto et al.
Ayumi Tsukamoto et al.
Background: Exposure to anticancer drugs is hazardous and may lead to chromosomal abnormalities and spontaneous abortion in healthcare workers. Guidelines recommend surface decontamination and cleaning in order to minimiz...
Validated determination method of tramadol and its desmethylates in human plasma using an isocratic LC-MS/MS and its clinical application to patients with cancer pain or non-cancer pain [0.03%]
一种人血浆中曲马多及其去甲基代谢物的LC-MS/MS测定方法的确证及其在癌症痛和非癌症痛患者中的应用研究
Hironari Tanaka,Takafumi Naito,Yasuaki Mino et al.
Hironari Tanaka et al.
Background: This study aimed to develop a simultaneous determination method for tramadol and its desmethylates in human plasma using isocratic liquid chromatography coupled to tandem mass spectrometry and to validate it f...
A novel predictive factor for the onset time of docetaxel-induced onychopathy: a multicenter retrospective study [0.03%]
多西他赛引起的甲板病変发生时间的新预测因素：一项基于多中心回顾性研究的结果
Hidenobu Takahata,Kouichi Tanabe,Akiyoshi Takaki et al.
Hidenobu Takahata et al.
Background: Taxanes are known to cause onychopathy. Previous studies have reported the relationship between onychopathy and paclitaxel dosing intervals and cumulative doses. However, there are no studies of the predictive...
Correlation between blood magnesium and calcium concentration in patients treated with an anti-EGFR antibody [0.03%]
抗EGFR抗体治疗患者的血镁与血钙浓度相关性分析
Toshiyasu Tsujii,Takafumi Ogaki,Kaori Nakae et al.
Toshiyasu Tsujii et al.
Background: Hypomagnesemia is one of the characteristic side effects of the human anti-epidermal growth factor receptor (EGFR) monoclonal antibodies, cetuximab and panitumumab. The major mechanism of anti-EGFR antibody-re...
Plasma tenofovir trough concentrations are associated with renal dysfunction in Japanese patients with HIV infection: a retrospective cohort study [0.03%]
日本HIV感染者的血浆替诺福韦谷浓度与肾脏功能损害的相关性：一项回顾性队列研究
Yusuke Kunimoto,Hiroshi Ikeda,Satoshi Fujii et al.
Yusuke Kunimoto et al.
Background: Plasma tenofovir (TFV) trough concentrations may be relevant for tenofovir disoproxil fumarate (TDF)-induced renal dysfunction. The purpose of this study was to determine the association between plasma TFV tro...