Development of an HPLC method using relative molar sensitivity for the measurement of blood concentrations of nine pharmaceutical compounds [0.03%]
一种相对摩尔灵敏度高效液相色谱法测定九种药物血药浓度的方法学研究
Takashi Ohtsuki,Yi Huang,Ayane Kamiya et al.
Takashi Ohtsuki et al.
We developed a reliable high-performance liquid chromatographic analysis method using a relative molar sensitivity (RMS) technique that does not require an authentic, identical reference analyte material to quantify blood serum carbamazepin...
Impact of polypharmacy on 3-year mortality in patients with heart failure: a retrospective study [0.03%]
一项回顾性研究：多种药物合并使用对心力衰竭患者3年生存率的影响
Daisuke Hayashi,Yoshiaki Kubota,Takuya Nishino et al.
Daisuke Hayashi et al.
Background: Guideline-directed medical therapy (GDMT) is important in heart failure management; however, polypharmacy itself may impact heart failure. Although measures against polypharmacy are needed, current discussion ...
Comparison of anticoagulation control and outcomes between usual medical care and pharmacist-led anticoagulation service in ambulatory patients taking warfarin at tertiary hospital in Ethiopia: a quasi-experimental study [0.03%]
埃塞俄比亚三级医院门诊接受华法林治疗的患者在接受药剂师主导的抗凝服务和常规医疗服务之间的抗凝控制及结果对比：一项准实验研究
Tamrat Assefa Tadesse,Amha Gebremedhin,Dejuma Yadeta et al.
Tamrat Assefa Tadesse et al.
Background: We aimed to compare anticoagulation control and outcomes between usual medical care (UMC) and pharmacist-led anticoagulation services (PLAS) in patients receiving warfarin at the Tikur Anbessa Specialized Hosp...
Case report of QT interval prolongation induced by anamorelin in an obese patient with non-small cell lung cancer [0.03%]
一例恶病质素诱发肥胖型非小细胞肺癌患者QT间期延长的病例报告
Hayato Yokota,Ruriko Asahi,Yumiko Akamine et al.
Hayato Yokota et al.
Background: Anamorelin, a drug to treat cancer cachexia, binds to ghrelin receptors and improves body weight and appetite. In clinical trials in Japan, patients experienced a 10.7% frequency of stimulant conduction system...
Evaluation of starch granules based on hydroxypropylcellulose as a substitute for excipient lactose [0.03%]
基于羟丙基纤维素的淀粉颗粒作为赋形剂乳糖替代品的评估研究
Tomohiro Yoshikawa,Hiroyo Okamoto,Kenta Takeuchi et al.
Tomohiro Yoshikawa et al.
Background: The improvement in flowability and adhesion of starch powder (SP) is essential for using starch as an excipient for lactose intolerant patients. In this study, we attempted to evaluate the usefulness of hydrox...
Association between roxadustat use and suppression of thyroid function: a systematic review and meta-analysis [0.03%]
罗沙司他使用与甲状腺功能抑制的相关性：系统评价和.meta.分析
Yuki Nakano,Satoru Mitsuboshi,Kazuhiro Tada et al.
Yuki Nakano et al.
Background: Based on several case reports and observational studies, there is a growing concern regarding the potential association between roxadustat, a hypoxia-inducible factor prolyl-hydroxylase inhibitor, and suppress...
Patient satisfaction with pharmacy services among users and non users of community based health insurance scheme at public health facilities in Gamo Zone, South Ethiopia: a comparative cross sectional study [0.03%]
社区卫生保险计划对提高公共医疗设施患者药学服务满意度的影响——以南埃塞俄比亚加莫区为例的比较横断面研究
Fitsum Teferi Gulta,Tidenek Mulugeta,Biruk Wogayehu et al.
Fitsum Teferi Gulta et al.
Background: Patient satisfaction is a crucial humanistic outcome metric in pharmacy services. There was a lack of evidence on patients' satisfaction with pharmacy services in Gamo zone among users and nonusers of the CBHI...
A case of successful contribution of therapeutic drug monitoring of valganciclovir as the prophylaxis against cytomegalovirus infection in a lung transplant recipient [0.03%]
缬更昔洛韦预防性用药血药浓度监测用于肺移植受者防治巨细胞病毒感染一例报告
Yoshiki Katada,Keisuke Umemura,Shunsaku Nakagawa et al.
Yoshiki Katada et al.
Background: Ganciclovir and its prodrug, valganciclovir, are first-line agents for cytomegalovirus infection prophylaxis after lung transplantation. Although valganciclovir prophylaxis is known to result in severe leukope...
Factors associated with incomplete adherence to integrase strand transfer inhibitor-containing single-tablet regimen among Japanese people living with HIV [0.03%]
日本HIV感染者的整合酶抑制剂单片制剂不完全依从性的相关因素分析
Yusuke Kunimoto,Shinichi Hikasa,Masashi Ishihara et al.
Yusuke Kunimoto et al.
Background: People living with human immunodeficiency virus (PLWH) require high rates of medication adherence to antiretroviral therapy (ART) for a successful treatment outcome. Understanding the factors associated with i...
Stage IV renal cell carcinoma achieves pathologic complete response after two ipilimumab plus nivolumab courses despite severe immune-related adverse events: a case report [0.03%]
一例严重的免疫相关不良事件后的达利珠单抗和纳武单抗治疗获得病理完全缓解的IV期肾细胞癌病例报告
Ryo Takada,Miki Fujiwara,Masatoshi Maki et al.
Ryo Takada et al.
Background: Ipilimumab (Ipi) plus nivolumab (Nivo) is the recommended first-line treatment for renal cell carcinoma (RCC). This report describes a case where pancreatic metastases disappeared after only two courses of Ipi...