Factors influencing the discontinuation of biologic therapies in patients with ulcerative colitis [0.03%]
影响溃疡性结肠炎患者停止使用生物制剂的因素
Arisa Fukuyama,Akio Nakashima,Motoyasu Miyazaki et al.
Arisa Fukuyama et al.
Background: The therapeutic landscape for ulcerative colitis (UC) has recently broadened to include anti-TNFα, anti-integrin, and anti-IL-12/23p40 antibody agents. These biological agents are tailored to individual patie...
A decision tree approach for investigating the background of research activity of community and hospital pharmacists in Mie Prefecture: a retrospective questionnaire-based survey [0.03%]
基于问卷的回溯性调查下决策树方法在三重县社区及医院药剂师从业人员背景与科研活动间关系的研究
Yuki Asai,Yasushi Takai,Hideo Kato et al.
Yuki Asai et al.
Background: The support system for research activities has not been sufficiently established in clinical settings. A survey should be conducted to identify the causes of low research activity among pharmacists and the cha...
Safety and efficacy of oxycodone for refractory dyspnea in end-stage heart failure patients with chronic kidney disease: a case series of eight patients [0.03%]
氨酚待因治疗终末期心脏衰竭合并慢性肾脏病患者的难治性喘憋的安全性和有效性：8例病例报告
Masayuki Tanaka,Hirofumi Maeba,Takeshi Senoo et al.
Masayuki Tanaka et al.
Background: Morphine is effective in palliative care for patients with end-stage heart failure; however, its use is avoided in patients with impaired renal function because it tends to induce adverse effects. Although oxy...
Usefulness of driver's eye movement measurement to detect potential risks under combined conditions of taking second-generation antihistamines and calling tasks [0.03%]
驾驶员在服用第二代抗组胺药物并进行通话任务时测量眼睛运动以检测潜在风险的有用性
Atsunobu Sagara,Akihito Nagahama,Hayato Aki et al.
Atsunobu Sagara et al.
Background: Concerns persist regarding the potential reduction in driving performance due to taking second-generation antihistamines or performing hands-free calling. Previous studies have indicated a potential risk to dr...
Assessing the effects of interprofessional education by hospital pharmacists on pharmaceutical students using a self-evaluation scale [0.03%]
住院药剂师评估跨专业教育对药学学生的影响使用的自我评价量表
Fuka Aizawa,Hirofumi Hamano,Naoto Okada et al.
Fuka Aizawa et al.
Background: Understanding the roles and competencies of professions outside of one's specialty is essential for providing efficient healthcare. However, it is difficult for medical professionals to understand the roles an...
Impact of automated pop-up alerts on simultaneous prescriptions of antimicrobial agents and metal cations [0.03%]
抗菌药物与金属阳离子配伍禁忌弹出警示干预效果的研究
Takanori Matsumoto,Taichi Matsumoto,Chiyo Tsutsumi et al.
Takanori Matsumoto et al.
Background: Antimicrobial agents (AMAs) are essential for treating infections. A part of AMAs chelate with metal cations (MCs), reducing their blood concentrations. That drug-drug interaction could lead to a reduction of ...
Influence of loop diuretics on denosumab-induced hypocalcaemia in osteoporosis: a retrospective observational analysis [0.03%]
利尿剂对骨质疏松患者地诺单抗致低钙血症影响的回顾性观察研究
Toshinori Hirai,Yukari Mori,Toru Ogura et al.
Toshinori Hirai et al.
Background: We examined whether denosumab-induced hypocalcaemia is evident in osteoporosis when given loop diuretics that promote urinary calcium excretion. ...
Effectiveness of tramadol-including multimodal analgesia in spinal surgery: a single-center, retrospective cohort study [0.03%]
含曲马多多模式镇痛在脊柱手术中应用的有效性研究——一项单中心回顾性队列研究
Misa Okizuka,Ryo Inose,Satoshi Makio et al.
Misa Okizuka et al.
Background: Multimodal analgesia (MMA) is recommended for postoperative pain management; however, studies evaluating the effect of tramadol-including MMA on numerical rating scale (NRS)-based postoperative pain levels and...
Comparison of kidney and hepatic outcomes among sodium-glucose cotransporter-2 inhibitors: a retrospective study using multiple propensity scores [0.03%]
钠葡萄糖协同转运蛋白-2抑制剂的肾脏和肝脏结局比较：使用多重倾向评分的回顾性研究
Kazuya Hiura,Chinami Suzuki,Junichi Kubo et al.
Kazuya Hiura et al.
Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) have been reported to have effects beyond lowering blood glucose levels, with certain SGLT2i expanding their indications to chronic kidney disease and chronic...
Changes in urinary output due to concomitant administration of sacubitril/valsartan and atrial natriuretic peptide in patients with heart failure: a multicenter retrospective cohort study [0.03%]
沙库巴曲缬沙坦与心房利钠肽联用对心力衰竭患者尿量影响的多中心回顾性队列研究
Tatsuki Yanagawa,Yuki Asai,Nobuyuki Zakoji et al.
Tatsuki Yanagawa et al.
Background: Sacubitril/valsartan is an angiotensin receptor neprilysin inhibitor (ARNI) that inhibits the degradation of endogenous natriuretic peptides. Therefore, ARNIs may increase the efficacy of human atrial natriure...