Efficacy of a melatonin receptor agonist and orexin receptor antagonists in preventing delirium symptoms in the olderly patients with stroke: a retrospective study [0.03%]
褪黑素受体激动剂和食欲素受体拮抗剂预防卒中老年人谵妄症状有效性的回顾性研究
Yukiko Miyoshi,Yuki Shigetsura,Daiki Hira et al.
Yukiko Miyoshi et al.
Background: Post-stroke delirium affects between 24% and 43% of patients, and negatively impacts patient outcomes. Recently, research attention has been on preventive interventions for delirium, with melatonin receptor ag...
Study on the chemical stability of β-lactam antibiotics in concomitant simple suspensions with magnesium oxide [0.03%]
镁橄榄石对复合颗粒增强铝基梯度功能材料显微组织与力学性能的影响研究
Ginjiro Kato,Hidemichi Mitome,Syu Takeda et al.
Ginjiro Kato et al.
Background: A simple suspension method, where solid formulations are disintegrated and suspended by being soaked in warm water followed by tube administration, is widely used, especially for elderly patients with dysphagi...
In-vivo evaluation of analgesic and anti-inflammatory activities of the 80% methanol extract of Acacia seyal stem bark in rodent models [0.03%]
啮齿动物模型中对Acacia seyal茎皮80%甲醇提取物止痛和抗炎活性的体内评价
Gena Kedir,Akeberegn Gorems Ayele,Workineh Shibeshi
Gena Kedir
Background: Pain and inflammation are the major medical condition commonly addressed with traditional remedies. Acacia seyal is a traditional herb widely used in Ethiopian folk medicine for pain management. However, its e...
Compatibility of hypokalaemia caused by low-dose prednisolone plus abiraterone acetate therapy for metastatic castration-resistant prostate cancer [0.03%]
低剂量泼尼松龙联合醋酸阿比特龙治疗转移性去势抵抗性前列腺癌所致低钾血症的相容性
Shota Torii,Aya Torii-Goto,Tamaki Tanizawa et al.
Shota Torii et al.
Background: This study aimed to investigate the relationship between low-dose prednisolone (PSL) and the incidence of hypokalaemia at abiraterone acetate (abiraterone) plus PSL combination therapy targeting Japanese patie...
Effects of famotidine use during pregnancy: an observational cohort study [0.03%]
妊娠期间使用法莫替丁的影响：一项观察性队列研究
Ayako Nishimura,Ayako Furugen,Masaki Kobayashi et al.
Ayako Nishimura et al.
Background: Famotidine, a histamine2-receptor antagonist (H2Ras), is widely used to treat and prevent gastrointestinal symptoms during pregnancy. Although several studies have reported the use of H2Ras during pregnancy, l...
A qualitative study on the current status and problems of pharmacists in home healthcare from the viewpoint of care managers in medically underpopulated areas in Japan [0.03%]
日本医疗人手不足地区居家护理药剂师的现况及问题定性研究（照护经理观点）
Yuji Nakagawa,Hideo Kato,Takuya Iwamoto
Yuji Nakagawa
Background: Unlike in urban areas, community healthcare in medically underpopulated areas in Japan is constantly challenged because of the uncertainty in effectively using the limited resources. However, no study has focu...
Development and validation of the prediction score for augmented renal clearance in critically Ill Japanese adults [0.03%]
危重症日本成人扩大肾清除率预测评分的制定与验证
Ryusei Mikami,Shungo Imai,Mineji Hayakawa et al.
Ryusei Mikami et al.
Background: Augmented renal clearance (ARC) decreases the therapeutic concentration of drugs excreted by the kidneys in critically ill patients. Several ARC prediction models have been developed and validated; however, th...
Investigating the hypothermic effects of fluoroquinolone antimicrobials on non-bacterial fever model mice [0.03%]
氟喹诺酮类抗菌药对非细菌感染发热模型小鼠低温效应的影响研究
Ryohei Hara,Kazuaki Taguchi,Hiromi Ogino et al.
Ryohei Hara et al.
Background: Fluoroquinolone (FQ) antimicrobials have antipyretic effects during the treatment of bacterial infections; however, it is not clear whether these are due to their antimicrobial activities or their hypothermic ...
Comparison of facilities with and without additional medical fees for nutrition support team activity during the COVID-19 pandemic [0.03%]
新冠肺炎疫情期间营养支持团队活动另收费用的设施与未另收费用的设施比较
Akihiko Futamura,Takenao Koseki,Junichi Iida et al.
Akihiko Futamura et al.
Background: This study aimed to clarify the effectiveness of nutrition support team (NST) facilities for preventing central line-associated bloodstream infection (CLABSI). ...
Abnormally high plasma concentrations of M-4, the active metabolite of edoxaban, at the onset of acute kidney injury in a patient receiving rifampin and clarithromycin: a case report [0.03%]
利福平和克拉霉素导致急性肾损伤患者接受艾多沙班治疗时，活性代谢产物M-4异常高的血浆浓度：病例报告
Junichi Nakagawa,Keinosuke Ishido,Norihisa Kimura et al.
Junichi Nakagawa et al.
Background: Edoxaban, the only factor Xa inhibitor with active metabolites, is metabolized by carboxylesterase-1 to its main active metabolite, M-4, which is a substrate of organic anion transporting polypeptide 1B1 (OATP...