Motor protein KIF13B orchestrates hepatic metabolism to prevent metabolic dysfunction-associated fatty liver disease [0.03%]
电机蛋白KIF13B协调肝代谢以防止与代谢功能障碍相关的脂肪肝疾病
Guo-Lin Miao,Wen-Xi Zhang,Yi-Tong Xu et al.
Guo-Lin Miao et al.
Background: Kinesin family member 13B (KIF13B), a crucial motor protein, exerts multiple cellular biological functions. However, the implication of KIF13B in metabolic dysfunction-associated fatty liver disease (MAFLD) ha...
Impact of targeting the platelet-activating factor and its receptor in cancer treatment [0.03%]
在癌症治疗中靶向血小板活化因子及其受体的影响
Kimya Qaderi,Arvin Shahmoradi,Anita Thyagarajan et al.
Kimya Qaderi et al.
The lipid mediator platelet-activating factor (PAF) and its receptor (PAFR) signaling play critical roles in a wide range of physiological and pathophysiological conditions, including cancer growth and metastasis. The ability of PAFR to int...
Xin-Ling Li,Yu-Qing Zhao,Li Miao et al.
Xin-Ling Li et al.
Bone tissue relies on the intricate interplay between blood vessels and nerve fibers, both are essential for many physiological and pathological processes of the skeletal system. Blood vessels provide the necessary oxygen and nutrients to n...
AKR1C3 as a therapeutic target to overcome erlotinib resistance in lung adenocarcinoma [0.03%]
AKR1C3作为克服肺癌腺癌厄洛替尼耐药性的治疗靶点
William C Cho,Kwan P Li,Chi F Wong et al.
William C Cho et al.
Tumor dormancy and relapse: understanding the molecular mechanisms of cancer recurrence [0.03%]
肿瘤休眠与复发：理解癌症复发的分子机制
Muhammad Tufail,Can-Hua Jiang,Ning Li
Muhammad Tufail
Cancer recurrence, driven by the phenomenon of tumor dormancy, presents a formidable challenge in oncology. Dormant cancer cells have the ability to evade detection and treatment, leading to relapse. This review emphasizes the urgent need t...
Exploring new horizons in CAR-based therapy for the treatment of thyroid-associated ophthalmopathy [0.03%]
基于CAR疗法治疗甲状腺相关性眼病的新进展探索
Xin-Yu Zhu,Wei-Yi Zhou,Tuo Li
Xin-Yu Zhu
Build the virtual cell with artificial intelligence: a perspective for cancer research [0.03%]
用人工智能建造虚拟细胞：癌症研究展望
Tao Yang,Yuan-Yi Wang,Fei Ma et al.
Tao Yang et al.
MELK prevents radiofrequency ablation-induced immunogenic cell death and antitumor immune response by stabilizing FABP5 in hepatocellular malignancies [0.03%]
MELK通过稳定FABP5来预防射频消融诱导的免疫原性细胞死亡和抗肿瘤免疫反应肝癌中
Bu-Fu Tang,Wang-Ting Xu,Shi-Ji Fang et al.
Bu-Fu Tang et al.
Background: Radiofrequency ablation (RFA) is an efficient treatment with unlimited potential for liver cancer that can effectively reduce patient mortality. Understanding the biological process related with RFA treatment ...
Short-term suborbital space flight curtails astronauts' dopamine levels increasing cortisol/BDNF and prompting pro-oxidative/inflammatory milieu [0.03%]
短期亚轨道空间飞行会缩短宇航员多巴胺水平并增加皮质醇/脑源性神经营养因子以引发促氧化/炎症环境
Gerardo Bosco,Angelo Landolfi,Tommaso Antonio Giacon et al.
Gerardo Bosco et al.