Artificial intelligence in orthopedics: fundamentals, current applications, and future perspectives [0.03%]
骨科的人工智能：基础、当前应用和未来展望
Jian Song,Guang-Chao Wang,Si-Cheng Wang et al.
Jian Song et al.
Conventional diagnostic and therapeutic approaches in orthopedics are frequently time intensive and associated with elevated rates of diagnostic error, underscoring the urgent need for more efficient tools to improve the current situation. ...
Toward phase contribution assessment in perioperative oncology: insights from NSCLC and a proposal for broader implementation [0.03%]
肺癌围手术期治疗阶段贡献评估的启示及推广建议
Hui-Yao Huang,Yan-Jie Han,Yu Tang et al.
Hui-Yao Huang et al.
Hai-Jia Yu,Jian-Hua Liu,Wei Liu et al.
Hai-Jia Yu et al.
The heterogeneity and invasiveness of cancer cells pose serious challenges in cancer diagnosis and treatment. Advancements and innovations in metal-based nanomedicines provide novel avenues for addressing these challenges. Metal-based nanom...
Ultrasound initiated tumor catalytic PANoptosis by mesoporous piezoelectric nanocatalysts [0.03%]
介电纳米催化剂超声触发肿瘤催化PANoptosis及中孔压电纳米催化剂诱导的肿瘤催化PANoptosis
Xuan-Shou Xu,Wei-Wei Ren,Heng Zhang et al.
Xuan-Shou Xu et al.
Background: PANoptosis has been identified as a robust inflammatory cell death pathway triggered upon host defense against invaded pathogens such as bacteria and viruses, however, pathogen-free tumor PANoptosis has not be...
Accelerating cartilage regeneration with DNA-SF hydrogel sustained release system-based cartilage organoids [0.03%]
基于DNA-SF水凝胶缓释系统的软骨类器官促进软骨再生
Cong-Yi Shen,Qi-Rong Zhou,Xiang Wu et al.
Cong-Yi Shen et al.
Background: Cartilage repair remains a considerable challenge in regenerative medicine. Despite extensive research on biomaterials for cartilage repair in recent years, issues such as prolonged repair cycles and suboptima...
Advancements in understanding tumor-resident bacteria and their application in cancer therapy [0.03%]
肿瘤驻留菌的研究进展及其在癌症治疗中的应用
Yi-Chen Luo,Xiu-Ting Huang,Rui Wang et al.
Yi-Chen Luo et al.
Recent advances in next-generation sequencing and bioinformatics have driven growing interest in the distinct roles of intratumoral microbiota, particularly intracellular bacteria, during tumor evolution. These bacteria increase the likelih...
Paul Freedman,Margot De Marco,Alessandra Rosati et al.
Paul Freedman et al.
Glucocorticoids trigger muscle-liver crosstalk to attenuate acute liver injury and promote liver regeneration via the FGF6-FGFBP1 axis [0.03%]
糖皮质激素通过FGF6-FGFBP1轴触发肌肉-肝脏交叉对话以减轻急性肝损伤和促进肝再生
Yue-Jie Xu,Cai-Zhi Liu,Ying Chen et al.
Yue-Jie Xu et al.
Background: Acute liver injury (ALI) requires rapid hepatic regeneration to avert fatal liver failure. As key mechanisms, systemic metabolic remodeling and inter-organ crosstalk are critical for this regenerative process....
Kui-Ying Yin,Tao Yu,Chuan Liu et al.
Kui-Ying Yin et al.
Background: Epilepsy is a neurological disorder characterized by recurrent seizures due to hyperexcitable neuronal network activity. The manifestations vary widely, ranging from subtle sensory disturbances to profound alt...
Building "walls" to stop pathogens: neutrophils play a role in the repair of extracellular matrix [0.03%]
构建"墙"来阻止病原体：中性粒细胞在基底膜外源性细胞间质修复中的作用
Feng-Ying Liao,Zhen Wang,Jian-Xin Jiang et al.
Feng-Ying Liao et al.