Validation of the Asian constipation assessment initiative questionnaire: a cross-sectional study on symptom reporting and constipation awareness [0.03%]
亚洲型便秘评估问卷的验证研究：一项关于症状报告和便秘意识的横断面调查研究
Shang Wei Song,Wei Ying Ng,Ni Yin Lau et al.
Shang Wei Song et al.
Objective: Current patient-reported outcome measures (PROMs) for chronic constipation (CC) have been predominantly developed for Western populations, often neglecting cultural factors critical to Asian contexts. This stud...
Albin Alex,Alex S Hong,Marcus Dimmock et al.
Albin Alex et al.
Objective: Recent evidence supports diagnosing coeliac disease without biopsy in patients with significantly elevated tissue transglutaminase (IgA-tTG) antibodies. However, the implementation of this no-biopsy approach re...
Quality of life and lived experience of patients with short bowel syndrome treated with teduglutide and weaning off home parenteral nutrition: a qualitative analysis of patient diaries [0.03%]
泰德古鲁肽治疗短肠综合征患者的生存质量及减停居家肠外营养体验的定性分析：病历日记资料
Brian Jurewitsch,Colette Peters,Carol Okamoto
Brian Jurewitsch
Objective: This study aimed to explore the lived experiences and coping strategies of patients with short bowel syndrome (SBS) prescribed teduglutide and weaning off home parenteral nutrition (HPN), and to compare the qua...
Non-invasive fibrosis tools lack clinical utility for identifying advanced fibrosis in Fontan-associated liver disease: a retrospective cohort study [0.03%]
非侵入性纤维化工具缺乏识别Fontan相关肝病患者晚期肝纤维化的临床价值：一项回顾性队列研究
Paul Armstrong,Aoife Moriarty,Robert Hughes et al.
Paul Armstrong et al.
Objective: Fontan-associated liver disease (FALD) results from haemodynamic changes following the Fontan procedure for congenital heart disease and is associated with poorer outcomes. The prevalence of Fontan is rising du...
Long-term effectiveness of allogeneic bone marrow-derived mesenchymal stromal cell therapy for complex perianal and rectovaginal fistulas in Crohn's disease: a retrospective case series [0.03%]
复杂肛周及直肠阴道瘘克罗恩病患者同种异体骨髓间充质基质细胞治疗的长期疗效：病例系列回顾研究
Julia Husman,Margarete Wardenga,Sophie Kirk et al.
Julia Husman et al.
Objective: Perianal fistulas in Crohn's disease (CD) are associated with a high burden of illness and their treatment is challenging. Recent data indicate promising short-term efficacy of bone marrow-derived mesenchymal s...
Enhanced liver fibrosis test facilitates stratification of people with alcohol use disorder in primary care [0.03%]
增强型肝纤维化检测促进初级保健中酒精使用障碍患者的分层管理
Alexander Hung,Charlotte Turner,Freya Rhodes et al.
Alexander Hung et al.
Objective: Alcohol-related liver disease (ArLD) is a leading cause of liver-related mortality, but affects a minority of people with alcohol use disorder (AUD). Of people with AUD, only those with ArLD require hepatologis...
Adebrelimab plus capecitabine versus capecitabine monotherapy for adjuvant treatment of high-risk resected cholangiocarcinoma (ACHIEVE): protocol for a phase II, multicentre, randomised controlled trial [0.03%]
阿德贝利单抗联合卡培他滨对比单药卡培他滨用于高危可切除胆管癌术后辅助治疗的多中心随机对照临床试验（ACHIEVE研究）：方案摘要
Yuan Cheng,Yaodong Zhang,Changxian Li et al.
Yuan Cheng et al.
Introduction: Cholangiocarcinoma (CCA) carries a high risk of recurrence even after curative resection. Capecitabine is standard adjuvant therapy, but recurrence rates remain significant, particularly in high-risk patient...
Triaging colorectal urgent referrals in the COVID-19 era using faecal immunochemical testing: a prospective UK real-world multicentre cohort study [0.03%]
新型冠状病毒肺炎时代应用免疫化学法检测粪便潜血筛查结直肠癌急诊转诊的分流策略：英国真实世界多中心队列研究
Gareth Walker,Supriya Balasubramanya,Joel Bowen et al.
Gareth Walker et al.
Objective: During the early COVID-19 pandemic, UK guidelines advocated faecal immunochemical tests (FIT) with a threshold of 10 µg/g to help secondary care clinicians triage urgent suspected colorectal cancer (CRC) refer...
Faecal occult blood testing: a review of its use and common misutilisation [0.03%]
粪便潜血试验：使用现状及常见误用概述
Gabriela Méndez,Lucía Rivera-Matos,Asim Shuja
Gabriela Méndez
Colorectal cancer (CRC) remains a leading cause of cancer-related morbidity and mortality worldwide, with early detection being crucial for improving patient outcomes. While colonoscopy is the gold standard for CRC screening, stool-based te...
Bone health, renal outcomes, and iron deficiency anaemia in proton pump inhibitor versus histamine-2 receptor antagonist users: a retrospective cohort study based on TriNetX global collaborative network data [0.03%]
一项基于TriNetX全球协作网络数据的回顾性队列研究：质子泵抑制剂与H2受体阻滞剂使用者的骨健康、肾脏结局和缺铁性贫血
To-Pang Chen,Ming-Ju Wu,Cheng-Hsu Chen et al.
To-Pang Chen et al.
Objective: Proton pump inhibitors' (PPIs) widespread use raises concerns about bone health, renal outcomes, and iron deficiency anaemia (IDA). We aim to address these concerns via comprehensive matching. ...
Comparative Study
BMJ open gastroenterology. 2025 Jul 13;12(1):e001723. DOI:10.1136/bmjgast-2024-001723 2025