Escalating anti-tumour necrosis factor exposure with reductions in surgical resection rates in paediatric inflammatory bowel disease: an 18-year real-world population-based cohort study [0.03%]
儿童炎症性肠病中抗肿瘤坏死因子的使用增加与手术切除率降低:一项为期18年的基于人群的队列研究
Zachary Green,Myrna Nicholas,Stephanie Vuijk et al.
Zachary Green et al.
Objective: To evaluate the relationship between anti-tumour necrosis factor (TNF) use and surgical resection rates in a regional paediatric inflammatory bowel disease (IBD) cohort. ...
Safety and effectiveness of the Colovac anastomosis protection device compared with diverting ileostomy after low anterior resection: protocol for an international, multicentre, prospective, non-randomised comparative study (SAFE-3) [0.03%]
结肠灌洗袋吻合口保护装置与回肠造口术在低位前切术后效果的比较:国际多中心前瞻性非随机对照研究(安全-3)方案报道
Clément Pastier,Patricia Sylla,Sang W Lee et al.
Clément Pastier et al.
Introduction: Diverting loop ileostomy (DLI) after low anterior resection for rectal cancer reduces the clinical consequences of anastomotic leakage but is associated with significant morbidity, impaired quality of life a...
Contemporary preoperative assessment for colorectal surgery: new insights and developments [0.03%]
结直肠手术的术前评估:新观点与进展
Joyce Ong,Michael Wylie,Malcolm G Dunlop et al.
Joyce Ong et al.
Preoperative assessment is a critical step for every patient undergoing major colorectal surgery. Increasingly, major colorectal resection is being safely performed in older and multimorbid patients. Many established tenets of preoperative ...
Long-term classification stability and treatment patterns of inflammatory bowel disease unclassified: a longitudinal observational study [0.03%]
长期分类稳定性及炎症性肠病未明确类型的治疗模式:一项纵向观察研究
Mario Andrea Latorre,Michael Rennie,Konstantina Rosiou et al.
Mario Andrea Latorre et al.
Objective: In patients presenting with inflammatory bowel disease (IBD), it may not be possible to diagnose ulcerative colitis (UC) or Crohn's disease (CD) and a classification of IBD Unclassified (IBD-U) is applied. We a...
Observational Study
BMJ open gastroenterology. 2026 Jun 11;13(1):e002339. DOI:10.1136/bmjgast-2026-002339 2026
Safety and efficacy of advanced combination therapies for treating inflammatory bowel disease in adults: a systematic review and meta-analysis [0.03%]
成人炎症性肠病综合治疗安全性和有效性的系统综述和meta分析
Shellie Radford,Daniel Arruda Navarro Albuquerque,Zara Najeeb et al.
Shellie Radford et al.
Objectives: To systematically synthesise available evidence on the safety of advanced combination therapy (ACT) in adults with inflammatory bowel disease (IBD), with secondary exploratory evaluation of efficacy outcomes. ...
Burden of non-cancer comorbidities and mortality in chronic pancreatitis: a retrospective cohort study [0.03%]
慢性胰腺炎非癌症合并症负担与死亡率:一项回顾性队列研究
Shauntelle Quammie,Adil Rashid,Rahul Munyal et al.
Shauntelle Quammie et al.
Objective: Chronic pancreatitis (CP) is a progressive fibro-inflammatory disease associated with increased comorbidity and mortality. This study aimed to characterise the natural history of CP by assessing comorbidity pre...
Evaluation of serrated lesion detection using different indicators: a single-centre, community-based, retrospective cohort study [0.03%]
基于社区的单中心回顾性队列研究:评估不同指标在锯齿状病变检测中的应用效果
Bernard Denis,Vigueneche Catinat,Laurianne Plastaras et al.
Bernard Denis et al.
Objective: There are inverse associations between both the adenoma detection rate (ADR) and the serrated lesion detection rate (SLDR) and the risk of postcolonoscopy colorectal cancer. We aimed to evaluate the SLDRs of co...
Development and validation of multivariable prognostic machine learning models to identify patients at risk for inadequate bowel preparation when undergoing colonoscopy: a prospective, multicentre study [0.03%]
多变量预后机器学习模型的发展和验证,用于识别结肠镜检查时肠道准备不足的患者:一项前瞻性多中心研究
Christoph Schramm,Carolin Hehn,Harald Curth et al.
Christoph Schramm et al.
Objective: Inadequate bowel preparation impairs the accuracy of colonoscopy and increases the burden on patients and healthcare systems. Consequently, the quality of bowel preparation is an important quality indicator. We...
Multicenter Study
BMJ open gastroenterology. 2026 May 14;13(1):e002238. DOI:10.1136/bmjgast-2025-002238 2026
Effectiveness and safety of mirikizumab in ulcerative colitis: real-world data from the Latium Net [0.03%]
Mirikizumab在溃疡性结肠炎患者中的有效性和安全性:拉齐奥网络真实世界数据
Marco Murgiano,Paola Balestrieri,Emma Calabrese et al.
Marco Murgiano et al.
Objective: To evaluate the effectiveness and safety of mirikizumab in patients with ulcerative colitis in clinical practice. Methods: W...
Multicenter Study
BMJ open gastroenterology. 2026 May 5;13(1):e002232. DOI:10.1136/bmjgast-2025-002232 2026
Using the enhanced liver fibrosis test to identify disease in at-risk populations [0.03%]
利用增强型肝纤维化检测法识别高危人群的疾病状况
Alex Hinkson,Jacob Feathers,Jason Punnamkuzhy et al.
Alex Hinkson et al.
Objective: Steatotic liver disease is common and has increased prevalence among those with type II diabetes mellitus or hazardous alcohol use. Identifying individuals with advanced liver disease early through screening ma...