Novel variant of EATL evolving from mucosal γδ-T-cells in a patient with type I RCD [0.03%]
一例类型I肠病相关T细胞淋巴瘤患者的黏膜γδ-T细胞演变为新型肠病相关T细胞淋巴瘤病例报告
R L J van Wanrooij,D de Jong,A W Langerak et al.
R L J van Wanrooij et al.
Objectives: Enteropathy associated T-cell lymphoma (EATL) is a rare non-Hodgkin lymphoma that may complicate coeliac disease and typically occurs in patients with refractoriness to the gluten-free diet. The majority of th...
The societal burden of chronic liver diseases: results from the COME study [0.03%]
欧洲慢性肝病的疾病负担：COMET 研究结果
Luciana Scalone,Stefano Fagiuoli,Roberta Ciampichini et al.
Luciana Scalone et al.
Objective: Chronic liver diseases (CLDs) impose a significant socioeconomic burden on patients and the healthcare system, but to what extent remains underexplored. We estimated costs and health-related-quality-of-life (HR...
Inflammation decreases keratin level in ulcerative colitis; inadequate restoration associates with increased risk of colitis-associated cancer [0.03%]
炎症通过降低溃疡性结肠炎中的角蛋白水平而增加结肠癌风险
Bernard M Corfe,Debabrata Majumdar,Arash Assadsangabi et al.
Bernard M Corfe et al.
Background: Keratins are intermediate filament (IF) proteins, which form part of the epithelial cytoskeleton and which have been implicated pathology of inflammatory bowel diseases (IBD). ...
Mohamed Amin El-Gohary
Mohamed Amin El-Gohary
Objective: To highlight a new phenomenon that we have encountered in children during the past 5 years. Children in this group have a pathognomonic clinical picture of sudden acute severe abdominal colic during which the c...
Reduced keratin expression in colorectal neoplasia and associated fields is reversible by diet and resection [0.03%]
结直肠肿瘤及其相关区域的角蛋白表达降低可通过饮食和切除逆转
Caroline A Evans,Ria Rosser,Jennifer S Waby et al.
Caroline A Evans et al.
Background: Patients with adenomatous colonic polyps are at increased risk of developing further polyps suggesting field-wide alterations in cancer predisposition. The current study aimed to identify molecular alterations...
Tacrolimus or infliximab for severe ulcerative colitis: short-term and long-term data from a retrospective observational study [0.03%]
他克莫司与英夫利昔单抗治疗重度溃疡性结肠炎短期和长期的回顾性研究数据
Naoki Minami,Takuya Yoshino,Minoru Matsuura et al.
Naoki Minami et al.
Objective: Treatment of severe ulcerative colitis (UC) is challenging. Although the efficacy of tacrolimus (TAC) and infliximab (IFX) have been evaluated in patients with severe UC, the safety and efficacy levels of seque...
Systematic review of genetic association studies involving histologically confirmed non-alcoholic fatty liver disease [0.03%]
涉及组织学证实的非酒精性脂肪肝病的遗传关联研究的系统评价
Kayleigh L Wood,Michael H Miller,John F Dillon
Kayleigh L Wood
Non-alcoholic fatty liver disease has an increasing prevalence in Western countries, affecting up to 20% of the population. Objective: The aim of this pro...
VSL#3 induces and maintains short-term clinical response in patients with active microscopic colitis: a two-phase randomised clinical trial [0.03%]
VSL#3诱导并维持活性显微镜下肠炎患者的短期临床反应：一项两阶段随机临床试验
Sarika Rohatgi,Vineet Ahuja,Govind K Makharia et al.
Sarika Rohatgi et al.
Background: The probiotic mixture VSL#3 has proven efficacious in inflammatory bowel diseases and irritable bowel syndrome; however, its efficacy in microscopic colitis (MC) is being investigated. ...
Choice of plastic or metal stent for patients with jaundice with pancreaticobiliary malignancy using simple clinical tools: a prospective evaluation [0.03%]
使用简单的临床工具评估胰胆恶性肿瘤黄疸患者塑料支架和金属支架置入的选择性：一项前瞻性研究
C Mel Wilcox,Hwasoon Kim,Toni Seay et al.
C Mel Wilcox et al.
Background and aim: Although plastic stents have been recommended for patients with pancreaticobiliary malignancy and an expected survival of less than 6 months, no study has developed criteria to assess survival which co...
The effects of auricular acupuncture on weight reduction and feeding-related cytokines: a pilot study [0.03%]
耳针减肥及对摄食相关细胞因子影响的试点研究
Hisayuki Ito,Osamu Yamada,Yuji Kira et al.
Hisayuki Ito et al.
Objective: Auricular acupuncture is a common therapy used to control appetite; however, the underlying mechanism(s) of action is unclear. The present study examined changes in feeding behaviour and in the levels of severa...