Circulating miRNA in patients with non-alcoholic fatty liver disease and coronary artery disease [0.03%]
非酒精性脂肪肝病和冠状动脉疾病患者的循环miRNA
Rohini Mehta,Munkzhul Otgonsuren,Zahra Younoszai et al.
Rohini Mehta et al.
Background: Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome and coronary artery disease (CAD) is the cardiac manifestation of metabolic syndrome. NAFLD is strongly linked to CA...
The first cases of collagenous sprue successfully treated with thioguanine [0.03%]
首例应用硫鸟嘌呤治疗胶原性小肠淋巴管病变取得成功的病例报告
Tom van Gils,Tine van de Donk,Gerd Bouma et al.
Tom van Gils et al.
Objective: Collagenous sprue (CS) is a rare form of small bowel enteropathy characterised by a thickened basement membrane and is, in most of the literature, reported as part of coeliac disease. Multiple treatment strateg...
Percutaneous endoscopic transgastric jejunostomy (PEG-J): a retrospective analysis on its utility in maintaining enteral nutrition after unsuccessful gastric feeding [0.03%]
经皮内镜下胃 jejunal 置管( PEG-J )在胃喂养失败后的肠内营养维持中的应用价值回顾性分析
Ezekiel Wong Toh Yoon,Kaori Yoneda,Shinya Nakamura et al.
Ezekiel Wong Toh Yoon et al.
Background/aims: Although percutaneous endoscopic gastrostomy (PEG) is the method of choice for long-term enteral nutrition, feeding-related adverse events such as aspiration pneumonia and peristomal leakage can impede th...
Persistent constipation and abdominal adverse events with newer treatments for constipation [0.03%]
持续性便秘及新治便秘方法的不良反应
Irene Sonu,George Triadafilopoulos,Jerry D Gardner
Irene Sonu
Background: Clinical trials of several new treatments for opioid-induced constipation (OIC), chronic idiopathic constipation (CIC) and constipation-predominant irritable bowel syndrome (IBS-C) have focused on differences ...
Multicentre prospective survey of SeHCAT provision and practice in the UK [0.03%]
英国UK关于SeHCAT的多中心前瞻性调查研究报告
Jennifer A Summers,Janet Peacock,Bolaji Coker et al.
Jennifer A Summers et al.
Objective: A clinical diagnosis of bile acid malabsorption (BAM) can be confirmed using SeHCAT (tauroselcholic ((75)selenium) acid), a radiolabelled synthetic bile acid. However, while BAM can be the cause of chronic diar...
Hepatic macrophages in liver fibrosis: pathogenesis and potential therapeutic targets [0.03%]
肝纤维化中的肝脏巨噬细胞：发病机制及潜在治疗靶点
Hai Li,Hong You,Xu Fan et al.
Hai Li et al.
Hepatic macrophages account for the largest non-parenchymal cell population in the liver. Recent studies have found that hepatic macrophages have different functions in different stages of experimental liver fibrosis. Some studies found tha...
Effectiveness of budesonide MMX (Cortiment) for the treatment of mild-to-moderate active ulcerative colitis: study protocol for a prospective multicentre observational cohort study [0.03%]
布地奈德-MMX（CORTIMENT）治疗轻至中度活动性溃疡性结肠炎疗效的前瞻性多中心队列观察研究方案
Silvio Danese,Ailsa Hart,Axel Dignass et al.
Silvio Danese et al.
Introduction: A study has been developed to assess the use and effectiveness of budesonide MMX for mild-to-moderate active ulcerative colitis (UC) in routine clinical practice. ...
Faecal microbiota transplantation: applications and limitations in treating gastrointestinal disorders [0.03%]
粪菌移植在治疗胃肠道疾病中的应用及局限性
Hani Sbahi,Jack A Di Palma
Hani Sbahi
The process of stool transfer from healthy donors to the sick, known as faecal microbiota transplantation (FMT), has an ancient history. However, only recently researchers started investigating its applications in an evidence-based manner. ...
Cost-effectiveness of adalimumab, infliximab or vedolizumab as first-line biological therapy in moderate-to-severe ulcerative colitis [0.03%]
中重度溃疡性结肠炎患者首次使用阿达木单抗、英夫利昔单抗或维多珠单抗治疗的性价比分析
Lauren Yokomizo,Berkeley Limketkai,K T Park
Lauren Yokomizo
Background: There are no head-to-head randomised controlled trials (RCTs) comparing the effectiveness of biologics in ulcerative colitis (UC). We aimed to assess the cost-effectiveness of adalimumab, infliximab and vedoli...
Initial US evaluation of second-generation capsule colonoscopy for detecting colon polyps [0.03%]
美国首次评估胶囊结肠镜检查在检测结肠息肉方面的效果
Douglas R Morgan,Pramod R Malik,David P Romeo et al.
Douglas R Morgan et al.
Objectives: Capsule colonoscopy is an additional screening modality for colorectal cancer. Second-generation capsule colonoscopy (CC2) may have improved efficacy in the detection of colon adenomas as compared with prior d...