Comparative evaluation of a hybrid machine learning-human adjudication paradigm for endoscopic scoring in ulcerative colitis [0.03%]
溃疡性结肠炎内镜评分的混合机器学习人工裁定范式的比较评估
Klaus T Gottlieb,Chakib Battioui,Yeli Wang et al.
Klaus T Gottlieb et al.
Objective: Endoscopic scoring of disease activity is essential in ulcerative colitis trials but is limited by inter-reader variability and operational complexity. We evaluated a novel central reading paradigm integrating ...
Comparative Study
BMJ open gastroenterology. 2025 Dec 7;12(1):e001959. DOI:10.1136/bmjgast-2025-001959 2025
Parasitic colitis misdiagnosis as inflammatory bowel disease in high-income settings and association with poor clinical outcomes when exposed to corticosteroids: a systematic review of case reports [0.03%]
误将寄生虫性结肠炎诊断为炎症性肠病及高收入地区误诊后使用皮质类固醇与较差临床结局之间的关联：病例报告的系统回顾
Robert D Lees,Jenna Fyfe,Laura M Woods et al.
Robert D Lees et al.
Objectives: Parasitic colitis is highly prevalent worldwide, may mimic inflammatory bowel disease (IBD) and is encountered by non-specialist physicians in high-income, non-endemic settings. In this context, patients may b...
Serrated polyps in the colorectum: clinical significance and future directions [0.03%]
结肠直肠锯齿状多发性息肉的临床意义及未来研究方向
Taha Rashid Mallick,Mahera Hasan
Taha Rashid Mallick
Serrated polyps are believed to play an important role in the development of colorectal cancer (CRC). They share molecular characteristics and proximal colonic location with postcolonoscopy colorectal cancer (PCCRC), indicating that they ma...
Utilisation and real-world effectiveness of advanced therapies for inflammatory bowel disease in Middle Eastern populations: a systematic review [0.03%]
中东风土人炎症性肠病的先进疗法的应用及实际有效性：系统评价研究
Mohammed Nabil Quraishi,Maryam A Alahmad,Ala I Sharara et al.
Mohammed Nabil Quraishi et al.
Objectives: We aimed to systematically review the real-world evidence (RWE) on the effectiveness and utilisation of advanced therapies for inflammatory bowel disease (IBD) in Middle Eastern populations. ...
Machine learning classification of inflammatory bowel disease activity using white blood cell subsets [0.03%]
基于白细胞亚群的机器学习算法在炎症性肠病诊断中的应用研究
Eleanor Lehman,Peyton Briand,Kyra Fine et al.
Eleanor Lehman et al.
Objective: The lack of a rapid, validated, consistent test for tracking disease activity in patients with inflammatory bowel disease (IBD) is currently a major challenge. Currently used biomarkers have notable disadvantag...
Actionable mutations in pancreatic cancer: where targeted therapies are making a difference [0.03%]
胰腺癌中的可操作突变：靶向治疗大有可为
Morgan Fivaz,Aurélie Bornand,Claudia Corro et al.
Morgan Fivaz et al.
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest solid tumours, with 5-year survival consistently below 10% and only modest gains from conventional chemotherapy after first-line failure. Although oncogenic KRAS mutations...
Non-invasive liver fibrosis scores and mortality in a cohort of World Trade Center rescue/recovery workers [0.03%]
世界贸易中心救援／回复工人队列中的非侵入性肝纤维化评分与死亡率关系研究
Ankura Singh,Rachel Zeig-Owens,Nikolina Icitovic et al.
Ankura Singh et al.
Objectives: Higher liver fibrosis scores have been associated with all-cause and liver disease-related mortality. We investigated whether liver fibrosis scores were associated with all-cause, liver disease-related and non...
Risk stratification of IBD-associated liver disease using routinely collected biomarkers from a large-scale real-world dataset [0.03%]
基于大规模真实世界数据集的IBD相关性肝病的风险分层研究
Zachary Green,Alex Z Kadhim,Lynn Win et al.
Zachary Green et al.
Objective: Inflammatory bowel disease (IBD)-associated liver diseases (IBDALDs) are associated with hepatobiliary damage and malignancy, with diagnosis often delayed by heterogeneous presentation. We evaluated whether rou...
Observational Study
BMJ open gastroenterology. 2025 Nov 13;12(1):e002028. DOI:10.1136/bmjgast-2025-002028 2025
Physician adenoma detection rates and risk of post-colonoscopy colorectal cancer in a sequential screening programme: a retrospective cohort study [0.03%]
结肠镜筛查项目中医生的腺瘤检出率和结肠镜检查后的结直肠癌风险：一项队列研究
Li Xie,Wenhong Wang,Guanglu Zhang et al.
Li Xie et al.
Objectives: Long-term colorectal cancer (CRC) monitoring is common in Asia, but assessing colonoscopy effectiveness through adenoma detection rates (ADRs) remains uncommon. This study aimed to identify potential associati...
Impact of antithrombotic therapy on colonoscopy outcomes in FIT-positive patients: implications for polyp detection, diverticulosis and normal findings [0.03%]
抗凝血治疗对FIT阳性患者肠镜结果的影响：对于息肉检出、憩室病和正常发现的意义
Naim Abu-Freha,Mifleh Tatour,Fadi Abu Baker et al.
Naim Abu-Freha et al.
Objective: Faecal immunochemical test (FIT) is widely used in colorectal cancer (CRC) screening, but the impact of antithrombotic therapy on colonoscopy outcomes remains unclear. This study aimed to compare polyp detectio...
Multicenter Study
BMJ open gastroenterology. 2025 Oct 23;12(1):e001922. DOI:10.1136/bmjgast-2025-001922 2025