Patient priorities and decision-making process when choosing between colonic investigation alternatives: a qualitative interview study [0.03%]
选择结肠检查方法时患者的优先项和决策过程：定性访谈研究
Campbell MacLeod,Shaun Treweek,Philip Wilson et al.
Campbell MacLeod et al.
Objective: To establish patients' perceptions of decision-making and prioritisation of test attributes when considering a colonic investigation. Methods: ...
Precision oncology for advanced-stage adenocarcinoma of the appendix: comprehensive molecular characterisation identifies actionable lesions and potential predictive biomarkers [0.03%]
晚期阑尾腺癌的精准肿瘤学：全面分子特征分析鉴定可操作病灶和潜在预测生物标志物
Sebastian Lange,Hannah Lisiecki,Simon Kreutzfeldt et al.
Sebastian Lange et al.
Objective: Appendiceal adenocarcinoma is a rare cancer with very limited therapeutic options. We aimed to determine whether molecular profiling of advanced appendiceal adenocancer can identify actionable therapeutic alter...
Evaluation of survival outcomes in patients receiving palliative home parenteral nutrition: a retrospective observational study [0.03%]
姑息性家庭肠外营养疗效的评价：回顾性观察研究
Kristie Huirong Fan,Pinal S Patel,Rebecca Maddison et al.
Kristie Huirong Fan et al.
Objective: Intestinal failure in advanced malignancy is most commonly due to mechanical bowel obstruction. Palliative home parenteral nutrition (HPN) is an option for such patients to meet their nutritional needs. However...
Observational Study
BMJ open gastroenterology. 2025 Aug 19;12(1):e001822. DOI:10.1136/bmjgast-2025-001822 2025
Increased 30-day mortality associated with weekend emergency admission for alcohol-related liver disease in England: a record-linkage study using the Clinical Practice Research Datalink [0.03%]
英国周末急诊酒精性肝病患者的30天内死亡率增加：利用临床实践研究数据链进行的记录关联分析
Keith Bodger,William Tench,Thomas Mair et al.
Keith Bodger et al.
Objective: Deficiencies have been highlighted in acute hospital care for alcohol-related liver disease (ARLD). Such problems may be worse at weekends (WEs). Increased 30-day mortality for WE admissions has been reported f...
Validation of the Asian constipation assessment initiative questionnaire: a cross-sectional study on symptom reporting and constipation awareness [0.03%]
亚洲型便秘评估问卷的验证研究：一项关于症状报告和便秘意识的横断面调查研究
Shang Wei Song,Wei Ying Ng,Ni Yin Lau et al.
Shang Wei Song et al.
Objective: Current patient-reported outcome measures (PROMs) for chronic constipation (CC) have been predominantly developed for Western populations, often neglecting cultural factors critical to Asian contexts. This stud...
Albin Alex,Alex S Hong,Marcus Dimmock et al.
Albin Alex et al.
Objective: Recent evidence supports diagnosing coeliac disease without biopsy in patients with significantly elevated tissue transglutaminase (IgA-tTG) antibodies. However, the implementation of this no-biopsy approach re...
Quality of life and lived experience of patients with short bowel syndrome treated with teduglutide and weaning off home parenteral nutrition: a qualitative analysis of patient diaries [0.03%]
泰德古鲁肽治疗短肠综合征患者的生存质量及减停居家肠外营养体验的定性分析：病历日记资料
Brian Jurewitsch,Colette Peters,Carol Okamoto
Brian Jurewitsch
Objective: This study aimed to explore the lived experiences and coping strategies of patients with short bowel syndrome (SBS) prescribed teduglutide and weaning off home parenteral nutrition (HPN), and to compare the qua...
Non-invasive fibrosis tools lack clinical utility for identifying advanced fibrosis in Fontan-associated liver disease: a retrospective cohort study [0.03%]
非侵入性纤维化工具缺乏识别Fontan相关肝病患者晚期肝纤维化的临床价值：一项回顾性队列研究
Paul Armstrong,Aoife Moriarty,Robert Hughes et al.
Paul Armstrong et al.
Objective: Fontan-associated liver disease (FALD) results from haemodynamic changes following the Fontan procedure for congenital heart disease and is associated with poorer outcomes. The prevalence of Fontan is rising du...
Long-term effectiveness of allogeneic bone marrow-derived mesenchymal stromal cell therapy for complex perianal and rectovaginal fistulas in Crohn's disease: a retrospective case series [0.03%]
复杂肛周及直肠阴道瘘克罗恩病患者同种异体骨髓间充质基质细胞治疗的长期疗效：病例系列回顾研究
Julia Husman,Margarete Wardenga,Sophie Kirk et al.
Julia Husman et al.
Objective: Perianal fistulas in Crohn's disease (CD) are associated with a high burden of illness and their treatment is challenging. Recent data indicate promising short-term efficacy of bone marrow-derived mesenchymal s...
Enhanced liver fibrosis test facilitates stratification of people with alcohol use disorder in primary care [0.03%]
增强型肝纤维化检测促进初级保健中酒精使用障碍患者的分层管理
Alexander Hung,Charlotte Turner,Freya Rhodes et al.
Alexander Hung et al.
Objective: Alcohol-related liver disease (ArLD) is a leading cause of liver-related mortality, but affects a minority of people with alcohol use disorder (AUD). Of people with AUD, only those with ArLD require hepatologis...