Mobile endoscopy in rural South Africa: outcomes of a decentralised outreach programme to improve gastrointestinal healthcare access [0.03%]
南非农村的移动内镜：一项提高胃肠保健可及性的分散型延伸项目的成果
Michael Deal,Joseph Karam,Shannon Rychener et al.
Michael Deal et al.
Introduction: Gastrointestinal (GI) endoscopy is a valuable diagnostic tool for identifying upper and lower GI pathologies yet is rarely available in resource-limited settings. This project evaluates the impact of a mobil...
Interventions for maintenance of surgically induced remission in Crohn's disease: a systematic review and network meta-analysis [0.03%]
维持克罗恩病手术缓解的干预措施：系统评价和网状meta分析
Morris Gordon,Shiyao Liu,Vassiliki Sinopoulou et al.
Morris Gordon et al.
Objectives: Approximately 50% of patients with Crohn's disease (CD) undergo surgery, and a significant proportion suffer from a post-surgical recurrence. We conducted a network meta-analysis to compare the efficacy of var...
Pruritus and health-related quality of life in chronic liver disease: a longitudinal, survey-based cohort study [0.03%]
慢性肝病患者瘙痒与健康相关生活质量关联：一项基于调查的队列研究
Usha Gungabissoon,Jake Hunnicutt,Eleanor J McDermott et al.
Usha Gungabissoon et al.
Objective: Cholestatic pruritus is commonly reported in primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC); however, information on pruritus in other chronic liver diseases (CLDs) is limited. This ...
Pouch excision, dysplasia and polypectomy in familial adenomatous polyposis ileal pouch anal anastomosis: a retrospective analysis [0.03%]
家族性腺瘤性 polyposis 回肠储袋肛管吻合术后储袋切除、原位癌和息肉切术的回顾性分析
Iain Blake,Hina Aslam,Shakil Ahmed et al.
Iain Blake et al.
Introduction: Familial adenomatous polyposis (FAP) is a rare autosomal dominant syndrome that, if untreated, carries a 100% lifetime risk of developing colorectal cancer. Proctocolectomy with ileal pouch-anal anastomosis ...
Comparative evaluation of a hybrid machine learning-human adjudication paradigm for endoscopic scoring in ulcerative colitis [0.03%]
溃疡性结肠炎内镜评分的混合机器学习人工裁定范式的比较评估
Klaus T Gottlieb,Chakib Battioui,Yeli Wang et al.
Klaus T Gottlieb et al.
Objective: Endoscopic scoring of disease activity is essential in ulcerative colitis trials but is limited by inter-reader variability and operational complexity. We evaluated a novel central reading paradigm integrating ...
Comparative Study
BMJ open gastroenterology. 2025 Dec 7;12(1):e001959. DOI:10.1136/bmjgast-2025-001959 2025
Parasitic colitis misdiagnosis as inflammatory bowel disease in high-income settings and association with poor clinical outcomes when exposed to corticosteroids: a systematic review of case reports [0.03%]
误将寄生虫性结肠炎诊断为炎症性肠病及高收入地区误诊后使用皮质类固醇与较差临床结局之间的关联：病例报告的系统回顾
Robert D Lees,Jenna Fyfe,Laura M Woods et al.
Robert D Lees et al.
Objectives: Parasitic colitis is highly prevalent worldwide, may mimic inflammatory bowel disease (IBD) and is encountered by non-specialist physicians in high-income, non-endemic settings. In this context, patients may b...
Serrated polyps in the colorectum: clinical significance and future directions [0.03%]
结肠直肠锯齿状多发性息肉的临床意义及未来研究方向
Taha Rashid Mallick,Mahera Hasan
Taha Rashid Mallick
Serrated polyps are believed to play an important role in the development of colorectal cancer (CRC). They share molecular characteristics and proximal colonic location with postcolonoscopy colorectal cancer (PCCRC), indicating that they ma...
Utilisation and real-world effectiveness of advanced therapies for inflammatory bowel disease in Middle Eastern populations: a systematic review [0.03%]
中东风土人炎症性肠病的先进疗法的应用及实际有效性：系统评价研究
Mohammed Nabil Quraishi,Maryam A Alahmad,Ala I Sharara et al.
Mohammed Nabil Quraishi et al.
Objectives: We aimed to systematically review the real-world evidence (RWE) on the effectiveness and utilisation of advanced therapies for inflammatory bowel disease (IBD) in Middle Eastern populations. ...
Machine learning classification of inflammatory bowel disease activity using white blood cell subsets [0.03%]
基于白细胞亚群的机器学习算法在炎症性肠病诊断中的应用研究
Eleanor Lehman,Peyton Briand,Kyra Fine et al.
Eleanor Lehman et al.
Objective: The lack of a rapid, validated, consistent test for tracking disease activity in patients with inflammatory bowel disease (IBD) is currently a major challenge. Currently used biomarkers have notable disadvantag...
Actionable mutations in pancreatic cancer: where targeted therapies are making a difference [0.03%]
胰腺癌中的可操作突变：靶向治疗大有可为
Morgan Fivaz,Aurélie Bornand,Claudia Corro et al.
Morgan Fivaz et al.
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest solid tumours, with 5-year survival consistently below 10% and only modest gains from conventional chemotherapy after first-line failure. Although oncogenic KRAS mutations...