Lucía Guilabert,Sara Nikolìc,Enrique de-Madaria et al.
Lucía Guilabert et al.
The incidence of incidental pancreatic cystic lesions (PCLs) has risen in recent years, largely due to advances in and increased use of imaging techniques. Endoscopic ultrasound (EUS) has become a crucial tool for evaluating and characteris...
Large language models for extracting histopathologic diagnoses of colorectal cancer and dysplasia from electronic health records [0.03%]
基于电子健康记录的结直肠癌和上皮内瘤变的大规模语言模型病理诊断提取系统
Brian Johnson,Tyler Bath,Xinyi Huang et al.
Brian Johnson et al.
Objective: Accurate data resources are essential for impactful medical research, but available structured datasets are often incomplete or inaccurate. Recent advances in open-weight large language models (LLMs) enable mor...
Integrative genome-wide analysis unveils the genetic landscape of gallstone disease and highlights novel loci with therapeutic potential [0.03%]
整合基因组分析揭示了胆囊结石疾病的遗传图谱并提出了具有治疗潜力的新位点
Haotian Chen,Zhengye Liu,Hanze Du et al.
Haotian Chen et al.
Objective: Gallstone disease (GD) is a common gastrointestinal disorder with a significant genetic component. Despite known risk factors, the genetic basis of GD remains incompletely understood. We aimed to identify novel...
Priya Mistry,Hannah J Leach,Elizabeth R Buse et al.
Priya Mistry et al.
Intestinal failure (IF) is defined as 'the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or...
Deep learning and capsule endoscopy: automatic panendoscopic detection of protruding lesions [0.03%]
深度学习与胶囊内镜:自动全内镜隆起病变检测
Miguel José Mascarenhas Saraiva,Maria João Almeida,Miguel Martins et al.
Miguel José Mascarenhas Saraiva et al.
Objective: Capsule endoscopy (CE) provides a minimally invasive exam modality for panendoscopic evaluation of the entire gastrointestinal (GI) tract. However, conventional reading methods can be time-consuming and error-p...
Limited utility of faecal immunochemical testing in a colorectal cancer screening programme for adults with cystic fibrosis: insights from a prospective UK study [0.03%]
粪便免疫化学检测在囊性纤维化成人结直肠癌筛查项目中的局限性:英国前瞻性研究的启示
Aqeem Azam,Karuna Sapru,Andrew M Jones et al.
Aqeem Azam et al.
Objective: People with cystic fibrosis (pwCF) are at significantly increased risk of colorectal cancer (CRC), prompting international recommendations for earlier screening with colonoscopy. The utility of faecal immunoche...
Pain experience of people with inflammatory bowel disease: a qualitative study [0.03%]
炎症性肠病患者疼痛体验的质性研究
Charlotte Beames,Afra Azadi,Amanda C de C Williams;ADVANTAGE Consortium
Charlotte Beames
Introduction: People with inflammatory bowel disease (IBD) commonly experience pain, whether during active disease or remission, which interferes with daily life and major goals and causes distress. Current psychological ...
Identification of robust associations between admission microbiome profiles and complications of acute pancreatitis [0.03%]
基于急性胰腺炎入院微生物组特征识别并发症的稳健关联
Hannah S Pauw,Hester C Timmerhuis,Marc Besselink et al.
Hannah S Pauw et al.
Objective: Patients with acute pancreatitis show reduced gut microbiome diversity and high abundance of pathogenic bacteria compared with healthy subjects. Admission microbiome profiles are increasingly linked to severity...
Multicenter Study
BMJ open gastroenterology. 2025 Sep 5;12(1):e001961. DOI:10.1136/bmjgast-2025-001961 2025
Upper gastrointestinal symptoms and Gulf War Illness in a clinical cohort of US veterans: a retrospective, cross-sectional study [0.03%]
上消化道症状与海湾战争综合征:一项美国退伍军人临床队列的回顾性横断面研究
Abdelrahman Yousef,Sarah T Ahmed,Theresa H Nguyen Wenker et al.
Abdelrahman Yousef et al.
Objective: Approximately 30% of the 700 000 US Gulf War Veterans (GWVs) report symptoms collectively termed Gulf War Illness (GWI), a multisymptom illness of uncertain pathophysiology. Prior studies in GWI focus on overla...
Etrasimod for the symptomatic relief of ulcerative colitis: a post-hoc analysis from the ELEVATE UC clinical programme [0.03%]
ELEVATE UC临床项目中etrastvimod用于溃疡性结肠炎对症治疗的亚组分析结果
María Chaparro,Remo Panaccione,Bruce E Sands et al.
María Chaparro et al.
Objective: Bothersome ulcerative colitis (UC) symptoms include stool frequency (SF), rectal bleeding (RB), abdominal pain and bowel urgency; symptomatic relief is a key treatment goal. Etrasimod is an oral, once-daily (QD...