Safety and efficacy of advanced combination therapies for treating inflammatory bowel disease in adults: a systematic review and meta-analysis [0.03%]
成人炎症性肠病综合治疗安全性和有效性的系统综述和meta分析
Shellie Radford,Daniel Arruda Navarro Albuquerque,Zara Najeeb et al.
Shellie Radford et al.
Objectives: To systematically synthesise available evidence on the safety of advanced combination therapy (ACT) in adults with inflammatory bowel disease (IBD), with secondary exploratory evaluation of efficacy outcomes. ...
Burden of non-cancer comorbidities and mortality in chronic pancreatitis: a retrospective cohort study [0.03%]
慢性胰腺炎非癌症合并症负担与死亡率：一项回顾性队列研究
Shauntelle Quammie,Adil Rashid,Rahul Munyal et al.
Shauntelle Quammie et al.
Objective: Chronic pancreatitis (CP) is a progressive fibro-inflammatory disease associated with increased comorbidity and mortality. This study aimed to characterise the natural history of CP by assessing comorbidity pre...
Evaluation of serrated lesion detection using different indicators: a single-centre, community-based, retrospective cohort study [0.03%]
基于社区的单中心回顾性队列研究：评估不同指标在锯齿状病变检测中的应用效果
Bernard Denis,Vigueneche Catinat,Laurianne Plastaras et al.
Bernard Denis et al.
Objective: There are inverse associations between both the adenoma detection rate (ADR) and the serrated lesion detection rate (SLDR) and the risk of postcolonoscopy colorectal cancer. We aimed to evaluate the SLDRs of co...
Development and validation of multivariable prognostic machine learning models to identify patients at risk for inadequate bowel preparation when undergoing colonoscopy: a prospective, multicentre study [0.03%]
多变量预后机器学习模型的发展和验证，用于识别结肠镜检查时肠道准备不足的患者：一项前瞻性多中心研究
Christoph Schramm,Carolin Hehn,Harald Curth et al.
Christoph Schramm et al.
Objective: Inadequate bowel preparation impairs the accuracy of colonoscopy and increases the burden on patients and healthcare systems. Consequently, the quality of bowel preparation is an important quality indicator. We...
Multicenter Study
BMJ open gastroenterology. 2026 May 14;13(1):e002238. DOI:10.1136/bmjgast-2025-002238 2026
Effectiveness and safety of mirikizumab in ulcerative colitis: real-world data from the Latium Net [0.03%]
Mirikizumab在溃疡性结肠炎患者中的有效性和安全性：拉齐奥网络真实世界数据
Marco Murgiano,Paola Balestrieri,Emma Calabrese et al.
Marco Murgiano et al.
Objective: To evaluate the effectiveness and safety of mirikizumab in patients with ulcerative colitis in clinical practice. Methods: W...
Multicenter Study
BMJ open gastroenterology. 2026 May 5;13(1):e002232. DOI:10.1136/bmjgast-2025-002232 2026
Using the enhanced liver fibrosis test to identify disease in at-risk populations [0.03%]
利用增强型肝纤维化检测法识别高危人群的疾病状况
Alex Hinkson,Jacob Feathers,Jason Punnamkuzhy et al.
Alex Hinkson et al.
Objective: Steatotic liver disease is common and has increased prevalence among those with type II diabetes mellitus or hazardous alcohol use. Identifying individuals with advanced liver disease early through screening ma...
Development and internal validation of the AGATE hybrid score for pre-endoscopic risk stratification in acute upper gastrointestinal bleeding: a single-centre, retrospective cohort study [0.03%]
AGATE混合评分的开发及内部验证在急性上消化道出血内镜前风险分层中的应用：单中心回顾性队列研究
Yavuz Özden,Ömer Yüzügülen,Ferhat Omurca
Yavuz Özden
Objective: To compare five established pre-endoscopic risk scores in acute upper gastrointestinal bleeding (AUGIB) and to derive a hybrid score (Acute Gastrointestinal Bleeding ABC-GBS Triage Evaluation (AGATE)) integrati...
Transarterial chemoembolisation-based combination therapy as a potential new standard for intermediate-stage hepatocellular carcinoma in the targeted immunotherapy era [0.03%]
靶向免疫治疗时代基于肝动脉化疗栓塞的联合治疗有望成为中期肝细胞癌的新标准治疗方法
Shuanggang Chen,Lujun Shen,Han Qi et al.
Shuanggang Chen et al.
Transarterial chemoembolisation (TACE) is the standard therapy for intermediate-stage hepatocellular carcinoma (HCC); however, its efficacy is limited by significant tumour heterogeneity. Recent landmark trials (EMERALD-1 and LEAP-012) demo...
Assessing the effect of single dose antibiotic prophylaxis compared with a multiday regimen in liver transplant recipients undergoing routine endoscopic retrograde cholangiopancreatography: a retrospective, single-centre, registry-based cohort study with a historical control group [0.03%]
单剂抗生素预防与多日方案在常规内镜逆行胰胆管造影的肝移植受者中的效果评估：一项基于登记表的队列研究，并设有历史对照组
Jessica Seeßle,Lara Ruhberg,Marietta Kirchner et al.
Jessica Seeßle et al.
Objective: Biliary complications, particularly anastomotic strictures, are common after liver transplantation (LT). The recommended duration of antibiotic prophylaxis after routine endoscopic retrograde cholangiopancreato...
Comparative Study
BMJ open gastroenterology. 2026 Apr 13;13(1):e002200. DOI:10.1136/bmjgast-2025-002200 2026
The 2026 IBD UK Standards of healthcare service design and delivery for adults and children living with Crohn's disease and ulcerative colitis [0.03%]
2026年英国炎症性肠病成人及儿童医疗服务标准
Christopher A Lamb,Catherine Picton,Ian Arnott et al.
Christopher A Lamb et al.
Objective: Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, requires consistent high-quality care to reduce variation in patient experience and improve outcomes. The IBD Standards previo...