Development of an optimal pathway for endoscopic sleeve gastroplasty implementation in the NHS: a modified nominal group technique study [0.03%]
英国国家医疗服务体系内内镜袖状胃成型术实施的优化路径开发：一种改良名义群体技术研究
Andrew Currie,Francis O&#x;Neill,Bu Hayee et al.
Andrew Currie et al.
Objective: The UK faces a significant obesity crisis, and multiple management options are now available, including pharmacotherapy, endoscopic and surgical interventions. Endoscopic Sleeve Gastroplasty (ESG) has emerged a...
Using an integrative multi-omics and in vitro approach to investigate the role of tris(2-butoxyethyl) phosphate in promoting hepatic steatosis [0.03%]
利用整合多组学和体外方法探究新污染物TBOEP促进肝脂肪变性的机制研究
Gang Zhou,Xihan Gu,Xinyao Zhou et al.
Gang Zhou et al.
Objective: To investigate the potential role of the environmental pollutant tris(2-butoxyethyl) phosphate (TBOEP) in the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD) and to elucidate it...
Association of extraintestinal manifestations and disease severity in paediatric inflammatory bowel disease: a multicentre cohort study [0.03%]
儿童炎症性肠病的肠外表现与疾病严重程度之间的关联：一项基于多中心队列的研究
Ágnes Eszter Tímár,Márk Hernádfői,Brigitta Teutsch et al.
Ágnes Eszter Tímár et al.
Objective: Extraintestinal manifestations (EIMs) are common in paediatric inflammatory bowel disease (IBD), often impairing quality of life. Our aim was to assess whether EIMs at diagnosis are associated with disease seve...
Multicenter Study
BMJ open gastroenterology. 2026 Feb 24;13(1):e002130. DOI:10.1136/bmjgast-2025-002130 2026
Evaluating treatment to a target of transmural healing in patients with moderately to severely active Crohn's disease: rationale, design and protocol for the randomised controlled VECTORS trial [0.03%]
评价针对中至重度活动性克罗恩病患者壁内愈合目标的治疗：随机对照VECTORS试验的理由、设计和方案
Vipul Jairath,Sudheer K Vuyyuru,Guangyong Zou et al.
Vipul Jairath et al.
Introduction: The optimal treatment target for Crohn's disease (CD) is unknown. Targeting transmural healing (TMH) may be associated with a lower risk of complications than clinical and endoscopic outcomes. The Study to E...
Assessment of transmural treatment response in known Crohn's disease: a prospective blinded study of the intermodality agreement between intestinal ultrasound and magnetic resonance enterography [0.03%]
肠超声和小肠磁共振在克罗恩病中的治疗反应的评价：一项前瞻性的盲法研究及两者之间的对比研究
Jacob Broder Brodersen,Søren Rafael Rafaelsen,Emilia Nejatbakhsh et al.
Jacob Broder Brodersen et al.
Objective: Intestinal ultrasound (IUS) and magnetic resonance enterography (MRE) are state-of-the-art modalities recommended for monitoring Crohn's disease (CD) activity and treatment response. This study aimed to examine...
Multicenter Study
BMJ open gastroenterology. 2026 Feb 9;13(1):e002175. DOI:10.1136/bmjgast-2025-002175 2026
Associations between patient characteristics and completeness of colon capsule endoscopy in colorectal cancer screening participants: a cross-sectional study [0.03%]
受试者特征与结直肠癌筛查中结肠胶囊内镜检查完整性的相关性：横断面研究
Lea Østergaard Hansen,Thomas Bjørsum-Meyer,Ola Selnes et al.
Lea Østergaard Hansen et al.
Objective: Incomplete investigations challenge the clinical use of colon capsule endoscopy (CCE). This results in added cost to healthcare systems and added discomfort to patients. In order to potentially lower the re-inv...
Research engagement and patient-reported quality of care: a cross-sectional study of UK inflammatory bowel disease services [0.03%]
英国炎症性肠病服务的科研参与度与患者报告的医疗质量：横断面研究
Robert J Mulligan,Pat Ryan,Lauren C Beck et al.
Robert J Mulligan et al.
Objective: Across several clinical specialties, research-active hospitals deliver higher-quality care and achieve better patient outcomes. To date, these associations have primarily been demonstrated using hospital-report...
Comparative efficacy, safety and compliance with dual, triple and quadruple therapy as the first-line treatment regimens for Helicobacter pylori eradication: a systematic review and network meta-analysis [0.03%]
双联、三联和四联疗法作为幽门螺杆菌根除一线治疗方案的有效性、安全性和依从性的系统评价和网络 Meta 分析
Iqbal Taufiqqurrachman,Ari Fahrial Syam,Hasan Maulahela et al.
Iqbal Taufiqqurrachman et al.
Objective: To assess the efficacy, safety and compliance with dual, triple and quadruple therapy first-line regimens for Helicobacter pylori eradication. ...
Proton-pump inhibitor exposure and prevalence of colorectal adenoma: a retrospective analysis from the Sakkopi study [0.03%]
质子泵抑制剂暴露与结直肠腺瘤患病率的关系：Sakkopi研究的回顾性分析
Hannah Hofer,Sarah Wernly,Andreas Völkerer et al.
Hannah Hofer et al.
Objective: Proton-pump inhibitors (PPIs) are among the most widely prescribed long-term medications worldwide, yet concerns remain about their potential role in colorectal carcinogenesis. Experimental data suggest that PP...
MOdel-informed precision dosing (MIPD) of ustekinumab and VEdolizumab in inflammatory bowel disease: protocol for an Independent randomised, controlled, multicentre Trial (MOVE-IT) [0.03%]
乌司奴单抗和维多珠单抗在炎症性肠病中的模型指导的精准剂量(MIPD)研究：一项独立随机对照多中心试验方案(移动试验)
Camilla Frimor,Casper Steenholdt,Ella Signe Kassandra Widigson et al.
Camilla Frimor et al.
Introduction: Biologic therapies, such as vedolizumab (VDZ) and ustekinumab (UST), offer effective treatment options for inflammatory bowel disease. In spite of limited evidence, it is common practice to escalate the dosi...