Adapting global guidelines to local contexts: optimising community-acquired pneumonia (CAP) specific prescribing in Pakistan to counter antimicrobial resistance [0.03%]
因地制宜适应全球指南:优化巴基斯坦社区获得性肺炎(CAP)的药物处方以应对抗菌素耐药性问题
Emmama Jamil,Muhammad Majid Aziz,Afreenish Amir et al.
Emmama Jamil et al.
Background/objectives: Community-acquired pneumonia (CAP) imposes a significant health burden among low- and middle-income countries. The burden is exacerbated by antimicrobial resistance (AMR), often due to inappropriate...
Impact of air pollution and asthma on school attendance and educational attainment: a scoping review [0.03%]
空气污染和哮喘对学校出勤率及教育成果影响的课题综述研究
Cedric Burden,Zakariah Gassasse,Mohammed Alsallakh et al.
Cedric Burden et al.
Background: Asthma morbidity is high among young people, and studies have shown associations between asthma and school attendance and educational attainment. However, findings are unclear concerning associations between a...
Multicentre controlled open randomised clinical trial to assess efficacy and safety of an anti-tuberculosis drug combination based on optimised-dose rifampicin, optimised-dose moxifloxacin and optimised-dose linezolid for TB: the RML-TB trial protocol [0.03%]
基于优化剂量利福平、莫西沙星和利奈唑胺的抗结核药物组合的有效性和安全性:RML-TB试验方案
Laura Diab Casares,Juan Espinosa Pereiro,María Teresa Tórtola Fernández et al.
Laura Diab Casares et al.
Introduction: International organisations, scientists and the tuberculosis (TB) community have been advocating for a shorter, safer treatment for drug-susceptible (DS)-TB with equal or better efficacy than current regimen...
Cost-effectiveness of a self-management maintenance programme following pulmonary rehabilitation: a UK randomised controlled trial for patients with chronic obstructive pulmonary disease [0.03%]
慢性阻塞性肺疾病患者完成肺康复后的自我管理维持项目的成本效益分析:一项英国随机对照试验
Amir J Khan,Anil Gumber,Matthew Richardson et al.
Amir J Khan et al.
Introduction: Pulmonary rehabilitation (PR) is an effective intervention for patients with chronic obstructive pulmonary disease (COPD) but impact typically only lasts 6-12 months. This paper presents results of an econom...
Randomized Controlled Trial
BMJ open respiratory research. 2025 Dec 4;12(1):e003406. DOI:10.1136/bmjresp-2025-003406 2025
Treatable moments for smoking cessation in asthma and COPD: a nationwide cohort study [0.03%]
基于全国人群队列研究的哮喘和慢阻肺患者戒烟时机分析
Delphine Vauterin,Adam Edward Lang,Kristiaan Proesmans et al.
Delphine Vauterin et al.
Background: Smoking cessation has proven to be the most effective non-pharmacological intervention to tackle poor outcomes in airway diseases. However, there is limited understanding of teachable/treatable moments (specif...
Prevalence of potentially inappropriate use of antiviral therapy with simnotrelvir-ritonavir versus nirmatrelvir-ritonavir in hospitalised patients: a retrospective study in Beijing, China [0.03%]
北京住院患者中含西蒙特拉韦和奈玛特韦的抗病毒疗法潜在不适当使用的流行病学:一项回顾性研究
Yuezhen Zhu,Yi Zhang,Hui Yang et al.
Yuezhen Zhu et al.
Background: While simnotrelvir-ritonavir and nirmatrelvir-ritonavir, the oral antiviral agents targeting the 3C-like proteases, are widely used in China, robust data on their appropriate use remain limited in hospitalised...
Comparative Study
BMJ open respiratory research. 2025 Dec 4;12(1):e003043. DOI:10.1136/bmjresp-2024-003043 2025
Retrospective cohort study of survival length in malignant pleural effusion between 2015 and 2023 [0.03%]
2015至2023年恶性胸腔积液生存期回顾队列研究
Craig Mounsey,Nikolaos Kanellakis,Dinesh Addala et al.
Craig Mounsey et al.
Background: Malignant pleural effusion (MPE) is common, affecting approximately 15% of patients with cancer. Over recent years, there have been significant changes in both the diagnostic and therapeutic strategies for the...
Development of the Cystic Fibrosis Stress Questionnaire: testing and validation [0.03%]
囊性纤维化应激问卷的制定:试验和验证
Carolyn J Snell,Morgan E Ryan,Isabel V Bailey et al.
Carolyn J Snell et al.
Objective: Care guidelines for cystic fibrosis (CF) recommend annual screening for anxiety and depression using standardised measures, the Patient Health Questionnaire (PHQ-9) and the Generalised Anxiety Disorder Scale (G...
Multicenter Study
BMJ open respiratory research. 2025 Dec 3;12(1):e003322. DOI:10.1136/bmjresp-2025-003322 2025
Denosumab usage is associated with better overall survival of patients with lung cancer and bone metastases: a retrospective cohort study [0.03%]
一项回顾性队列研究:地诺单抗的使用与肺癌伴骨转移患者总体生存率改善相关
Chung Chi Yu,Ho-Shen Lee,Jiun-Ting Wu et al.
Chung Chi Yu et al.
Background: Lung cancer with progressive bone metastases usually leads to skeletal-related events (SREs) and a reduced quality of life. Denosumab delays the onset of SREs and is associated with improved overall survival. ...
Current practices, perceptions and future challenges in the management of moderate to severe COPD: a cross-sectional survey of respiratory consultants in the Republic of Ireland [0.03%]
中至重度慢阻肺的当前管理实践、认知及未来挑战——爱尔兰共和国呼吸科医生横断面调查
Jayleigh Lim,Helen OBrien,Jack McCarthy et al.
Jayleigh Lim et al.
Introduction: Evidence is growing for interventions beyond inhaled therapies in chronic obstructive pulmonary disease (COPD). Clinician attitudes and access to these therapies are crucial to informing COPD care pathways. ...