Closing the Numeracy Gap in Medication Safety: Impact of a safeMedicate Intervention in Undergraduate Medical Education [0.03%]
安全用药干预对医学教育的作用：safeMedicate干预在医学教育中的影响
Soban Sadiq,Susan Driver,Manfred Gschwandtner
Soban Sadiq
Medication errors, often linked to inadequate numeracy skills, pose significant risks to patient safety. To address this, Kent and Medway Medical School (KMMS) became the first UK medical school to integrate safeMedicate, a validated e-lear...
A Single Dose, Randomized, Open-Label, Cross-Over Bioequivalence Study of Budesonide Pressurized Metered-Dose Inhaler in Healthy Chinese Subjects [0.03%]
布地奈德压氏吸气雾剂在中国受试者中的单次给药、随机开放标签、双期交叉生物等效性研究
Kai Huang,Shaohong Yin,Weiguo Huang et al.
Kai Huang et al.
Budesonide is a first-line inhaled glucocorticoid (ICS) for asthma treatment in adults and children. The purpose of this study was to compare the pharmacokinetics and assess the bioequivalence between two budesonide pressurized metered-dose...
Randomized Controlled Trial
Pharmacology research & perspectives. 2025 Dec;13(6):e70197. DOI:10.1002/prp2.70197 2025
Correction to "The MAO-B Inhibitor Selegiline Reduces the Viability of Different Prostate Cancer Cell Lines and Enhances the Effects of Anti-Androgen and Cytostatic Agents" [0.03%]
“MAO-B抑制剂司来吉兰降低不同前列腺癌细胞系的存活率并增强抗雄激素和细胞毒性药物的作用”的纠正意见
Published Erratum
Pharmacology research & perspectives. 2025 Dec;13(6):e70198. DOI:10.1002/prp2.70198 2025
Unbiased microRNA-Disease Association Prediction Using ICD-11 Codes and Negative Sampling [0.03%]
基于ICD-11代码和负样本采样的无偏miRNA疾病关联预测方法
Munyoung Chang,Jeonghee Jo,Junyong Ahn et al.
Munyoung Chang et al.
We developed a computational model, called "Unbiased microRNA-disease association predictor (UBMDA)," to predict microRNA-disease associations. UBMDA has two major differences from those reported previously. First, we did not apply a simila...
Impact of Dihydrocapsaicin on the Metabolism of Efavirenz In Vitro and In Vivo [0.03%]
二氢辣椒素对埃夫替拉韦代谢的体内外影响研究
Bo Wang,Xu Ma,Xinggao Wang et al.
Bo Wang et al.
Efavirenz (EFV) is the first-line treatment for acquired immunodeficiency syndrome. However, capsaicin may affect its properties, although the underlying mechanisms remain unknown. This study aimed to investigate the effects of dihydrocapsa...
Effects of Botrychium ternatum (Thunb) Sw. On Cytochrome P450 Activities in Rats [0.03%]
Botrychium ternatum (Thunb) SW.对大鼠细胞色素P450活性的影响
Jiange Yao,Liming Hu,Quan Zhou et al.
Jiange Yao et al.
Drug interactions commonly occur through the activities of cytochrome P450 (CYP). In this study, we evaluated the effects of the Chinese herbal medicine Botrychium Ternatum (Thunb) Sw. (BT) on six CYP enzymes. Twelve healthy male Sprague-Da...
Evaluating Rational Drug Use in Developing Countries: A Cross-Sectional Analysis of Prescribing Patterns Against WHO Indicators in Pakistan and Yemen [0.03%]
依据WHO指标评估发展中国家合理用药水平——以巴基斯坦和也门为例的横断面研究
Amjad Khan,Ali Mohammed Ahmed Al-Subari,Saima Mushtaq et al.
Amjad Khan et al.
The rational use of medications is essential for optimal healthcare delivery, especially in developing countries. This research delves into prescribing patterns within the healthcare system of Pakistan and Yemen against World Health Organiz...
Vasoactivity of Rac GTPase, Cytohesin and Kinase Inhibitors in Renal Interlobar and Coronary Arteries Reveals Shared and Distinct Patterns of Inhibitory Effects in Vascular and Prostate Smooth Muscle Contraction [0.03%]
Rac鸟苷三磷酸酶、细胞黏附蛋白和激酶抑制剂对肾叶间动脉和冠状动脉的血管活性反映出了其在血管和平滑肌收缩中具有相同及不同的抑制效应模式
Guangyang Liu,Sheng Hu,Alexander Tamalunas et al.
Guangyang Liu et al.
Inhibition of vasocontraction accounts for side effects in treating voiding symptoms in benign prostatic hyperplasia (BPH). We examined the vasoactivity of compounds previously showing inhibition of prostate smooth muscle contraction. Contr...
Polymyxin B Induced Acute Diaphragmatic Paralysis: A Case Report Based on Therapeutic Drug Monitoring [0.03%]
多黏菌素B致急性膈神经麻痹1例及治疗药物监测报告
Yunli Zhang,Xiaogang Tang,Yan Li et al.
Yunli Zhang et al.
Polymyxin B (PMB), a last-resort antibiotic for multidrug-resistant Gram-negative infections, carries significant neurotoxicity risks that remain underrecognized in clinical practice. Here, we present a case of life-threatening diaphragmati...
A Real-World Disproportionality Analysis of Avacopan in Anti-Neutrophil Cytoplasmic Antibodies Associated Vasculitis: Insights From FDA Adverse Event Reporting System [0.03%]
来自FDA不良事件报告系统的现实世界分析：Avacopan在抗中性粒细胞胞浆抗体相关性血管炎中的不对比例析及启示
Guojun Liang,Xiaofang Liu,Mengge Gao et al.
Guojun Liang et al.
Avacopan, an oral C5a receptor antagonist approved for treating anti-neutrophil cytoplasmic antibodies (ANCA) associated vasculitis, has established efficacy and short-term safety from clinical trials, but its post-marketing adverse events ...