Paeonol Inhibits Cell Growth by Inducing Ferroptosis in Human Glioma Cells [0.03%]
芍药醇通过诱导胶质瘤细胞铁死亡抑制细胞生长
Xin Li,Xue-Qi Liao,Wen-Rui Chen et al.
Xin Li et al.
Paeonol (PAE), a phenolic phytochemical derived from traditional Chinese medicinal plants, exhibits multifaceted pharmacological properties including demonstrated antitumor efficacy against hepatic, gastric, and breast carcinomas. However, ...
Gut Microbial Variations Associated With Proton Pump Inhibitor Use in the Boston Puerto Rican Health Study [0.03%]
波士顿波多黎各人健康研究中质子泵抑制剂使用与肠道微生物变化的关系
Deepika Dinesh,Xochitl C Morgan,Hanseul Kim et al.
Deepika Dinesh et al.
Proton pump inhibitors (PPI), used to treat gastrointestinal disorders, are associated with alterations in the gut microbiome. However, this is understudied in Puerto Ricans who have unique lifestyle characteristics. Puerto Ricans, includin...
Shifting the National Paradigm: From DEIA to C.A.R.E. (Community, Advocacy, Resilience, and Empowerment) in Pharmacy Education [0.03%]
从DEIA到C.A.R.E.(社区、倡导、复原力和赋权)：药学教育国家范式的转变
L&#x; Aurelle Johnson,Caroline Gaither,Olihe Okoro et al.
L&#x; Aurelle Johnson et al.
Fluoroquinolone-Associated Psychiatric and Ocular Adverse Events: A Disproportionality Analysis Using Real-World Data From FAERS (2011-2024) [0.03%]
氟喹诺酮类药物相关的精神和眼部不良事件：使用来自FAERS（2011-2024）的真实世界数据进行 disproportionality 分析
Hau-Tak Chau,Ngan Pan Bennett Au
Hau-Tak Chau
Fluoroquinolones (FQs) are widely prescribed antibiotics; however, increasing concerns have arisen over their potential to cause disabling and irreversible adverse effects. Using real-world data from the FDA Adverse Event Reporting System (...
Johannes Heck,Benjamin Krichevsky,Martin Schulze Westhoff et al.
Johannes Heck et al.
This study sought to investigate the frequency and characteristics of duplicate prescriptions (DPs) in psychiatric inpatients with substance use disorders using a DP classification that differentiates between appropriate DPs (ADPs) and pote...
Simon B Dimmitt,Hans G Stampfer,Michael C Kennedy et al.
Simon B Dimmitt et al.
The management of risk factors and timely revascularisation continues to reduce the morbidity and mortality from cardiovascular disease. Despite good evidence for reduced mortality on statins and decades of promotion, population uptake glob...
Glycine Reverses Behavioral Deficits in a Mouse Model for Psychosis With 4 Copies of the Gldc Gene [0.03%]
甘氨酸通过增加Gldc基因剂量逆转精神行为异常
Muxiao Wang,Maltesh Kambali,Jinrui Lyu et al.
Muxiao Wang et al.
A duplication/triplication copy number variant in the 9p24.1 chromosomal region with the additional gene copies being located on a small supernumerary marker chromosome has been identified in patients with psychosis. Mice genetically engine...
E J Kuijer,L H Marinelli,S J Bailey et al.
E J Kuijer et al.
Nalfurafine is the only clinically approved kappa opioid receptor (KOPr) agonist that can cross the blood-brain barrier and exert CNS effects. Because its clinical use is not associated with dysphoria, it is widely believed to have an atypi...
Peripheral Neuropathy Associated With Proteasome Inhibitors and Immunomodulatory Drugs: A Pharmacovigilance Disproportionality Analysis Using VigiBase [0.03%]
蛋白酶体抑制剂和免疫调节药物相关周围神经病变：源于VigiBase的药物警戒信号分析
Letícia Penna Braga,Cristiane Aparecida Menezes de Pádua,Iwyson Henrique F da Costa et al.
Letícia Penna Braga et al.
Immunomodulatory drugs (IMIDs) and proteasome inhibitors (PIs) are part of the frontline treatment landscape for multiple myeloma (MM). Despite their effectiveness, these drugs are associated with adverse effects, particularly clinically si...
Effect of Thrombopoietin Receptor Agonist Romiplostim on the Ionizing Radiation-Induced Premature Aging [0.03%]
血小板生成素受体激动剂罗米司亭对离子辐射所致早衰的影响
Masaru Yamaguchi,Tokuhisa Hirouchi,Yoshiaki Sato et al.
Masaru Yamaguchi et al.
Environmental stressors, such as ionizing radiation, accelerate aging by causing DNA damage and triggering pathways that lead to cell cycle arrest, apoptosis, and subsequent inflammation. The thrombopoietin receptor agonist romiplostim (RP)...