Monica Patel,Dharshini Ganeshan,Izzy Horgan et al.
Monica Patel et al.
Synthetic cannabinoids remain one of the most prominent classes of New Psychoactive Substances (NPS). The introduction of "blanket bans" has only invigorated the development and emergence of novel compounds. Recently, a putative synthetic c...
The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021-2025 State-of-the-Art Review of Clinical and Preclinical Evidence [0.03%]
他汀类药物在帕金森病和阿尔茨海默病中的应用：2021-2025年临床及前临床证据的前沿综述
Luigi Maria Chiatto,Lucia Buccarello,Giuseppe Carota et al.
Luigi Maria Chiatto et al.
Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease-modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and...
Investigation of the Effects of Methylphenidate on Hemodynamic Parameters in Children With ADHD [0.03%]
关于哌甲酯对注意缺陷多动障碍儿童的血流动力学影响的研究
Caglar Charles Daniel Jaicks,Selman Vefa Yıldırım
Caglar Charles Daniel Jaicks
This prospective observational study investigated the acute effects of a single 10 mg dose of methylphenidate (MPH) on hemodynamic and electrocardiographic parameters in 60 children aged 6-16 years newly diagnosed with Attention Deficit Hyp...
Observational Study
Pharmacology research & perspectives. 2026 Jun;14(3):e70276. DOI:10.1002/prp2.70276 2026
Investigating the Phytochemical Constituents, Anti-Inflammatory, and Neuropharmacological Activities of Podocarpus neriifolius Leaves Through FT-IR, GC-MS, Experimental Studies, Molecular Docking, and Molecular Dynamics Simulations [0.03%]
基于FT-IR、GC-MS、实验研究、分子对接和分子动力学模拟的Podocarpus neriifolius叶部位化学成分、抗炎和神经药理活性的研究
Neamul Hoque,Md Tashrif Rahman Tipu,Md Abul Bashar et al.
Neamul Hoque et al.
Podocarpus neriifolius, a widely distributed medicinal plant in South and Southeast Asia, has traditionally been used to treat rheumatism and joint pain. This study aimed to investigate the phytochemical profile and therapeutic potential of...
Proton Pump Inhibitors Prescribing Behaviors and Rationalization Strategies Among Healthcare Providers in Southeast Asia [0.03%]
东南亚医疗保健提供者处方质子泵抑制剂的行为及合理化策略
Duc Trong Quach,Tien Manh Huynh,Augusto Jose G Galang et al.
Duc Trong Quach et al.
Despite widespread use, real-world evidence regarding proton pump inhibitor (PPI) prescribing and rationalization practices in Southeast Asia (SEA) remains limited; therefore, we aimed to characterize current prescribing behaviors and ratio...
Morphological and Biochemical Insights Into the Renoprotective Effects of Combined N-Acetylcysteine and Glycine Treatment in Experimental Diabetic Nephropathy [0.03%]
N-乙酰半胱氨酸和甘氨酸联合治疗对实验性糖尿病肾病保护作用的形态学和生化学见解
Malik Ejubović,Andrej Belančić,Yun Wah Lam et al.
Malik Ejubović et al.
Diabetic nephropathy (DN) is a major microvascular complication of diabetes mellitus and the leading cause of end-stage renal disease. Oxidative stress and inflammation are central drivers of DN progression, yet no effective therapies exist...
The Prophylactic Effect of Dexmedetomidine 0.008% Versus Brimonidine 0.2% on IOP Elevation After Nd: YAG Laser Capsulotomy [0.03%]
0.008%右美托咪定与0.2%溴莫尼定预防Nd：YAG激光后囊切开术后眼压升高的疗效比较
Parisa Zakeri,Ghodrat Akhavanakbari,Habib Ojaghi et al.
Parisa Zakeri et al.
Posterior capsule opacification (PCO) is a common post-cataract surgery complication treated with Nd:YAG laser posterior capsulotomy, which may cause intraocular pressure (IOP) spikes and threaten vision. Brimonidine and apraclonidine are w...
Randomized Controlled Trial
Pharmacology research & perspectives. 2026 Jun;14(3):e70227. DOI:10.1002/prp2.70227 2026
Acceptability of Atropine Eyedrops Administered Sublingually for Sialorrhea Treatment Related to Neurological Conditions [0.03%]
舌下给药东莨菪碱滴眼液治疗神经病理性流涎的可行性研究
Hugues Michelon,Clémence Lefèvre-Dognin,Julie Paquereau et al.
Hugues Michelon et al.
Off-label use of anticholinergic agents (atropine eye drops) administered sublingually are a first-line treatment in standard clinical practice in France to treat sialorrhea in patients with neurological conditions. The ability and willingn...
Multicenter Study
Pharmacology research & perspectives. 2026 Jun;14(3):e70250. DOI:10.1002/prp2.70250 2026
Impact of FCGR2A and FCGR3A Gene Variants on the Response to Rituximab in Patients With Glomerular Diseases [0.03%]
FCGR2A和FCGR3A基因多态性对免疫吸附联合利妥昔单抗治疗难治性原发肾小球疾病疗效的影响
María Larrosa-García,Irene Agraz Pamplona,Susana Rojo Tolosa et al.
María Larrosa-García et al.
Rituximab is an anti-CD20 monoclonal antibody used in autoimmune diseases, including glomerular diseases. The FCGR2A (rs1801274) and FCGR3A (rs396991) variants have been suggested to affect rituximab efficacy; this study evaluates their imp...
Evaluating the Educational Value of Artificial Intelligence in Pharmacotherapy Education [0.03%]
评估人工智能在药物治疗学教育中的价值
Mariëlle G Hartjes,Michiel J Bakkum,Milan C Richir et al.
Mariëlle G Hartjes et al.
Final-year medical students frequently make prescribing errors, partly because they have had insufficient training in therapeutic reasoning. Students need to understand the underlying rationale behind a drug choice in order to subsequently ...