Metastatic malignant struma ovarii with coexistence of Hashimoto's thyroiditis [0.03%]
桥本甲状腺炎伴发卵巢恶性畸胎瘤转移案
Marco Russo,Ilenia Marturano,Romilda Masucci et al.
Marco Russo et al.
Struma ovarii is a rare ovarian teratoma characterized by the presence of thyroid tissue as the major component. Malignant transformation of the thyroidal component (malignant struma ovarii) has been reported in approximately 5% of struma o...
Coexistence of resistance to thyroid hormone and papillary thyroid carcinoma [0.03%]
抵抗甲状腺激素与乳头状甲状腺癌共存
Motoyuki Igata,Kaku Tsuruzoe,Junji Kawashima et al.
Motoyuki Igata et al.
Resistance to thyroid hormone (RTH) is a syndrome of reduced tissue responsiveness to thyroid hormones. RTH is majorly caused by mutations in the thyroid hormone receptor beta (THRB) gene. Recent studies indicated a close association of THR...
Manas Ghosh,Ambarish Bhattacharya,Kaushik Ghosh et al.
Manas Ghosh et al.
Motor neuron disease (MND) is a progressive devastating neurodegenerative disease, which universally progresses towards death. Hence, every attempt should be made to find out if there are any treatable conditions, which can mimic MND. Herei...
An unusual phenotype of MEN1 syndrome with a SI-NEN associated with a deletion of the MEN1 gene [0.03%]
与MEN1基因缺失相关的以SI-NEN为主的MEN1综合症罕见表现型
Jerena Manoharan,Caroline L Lopez,Karl Hackmann et al.
Jerena Manoharan et al.
We report about a young female who developed an unusual and an aggressive phenotype of the MEN1 syndrome characterized by the development of a pHPT, malignant non-functioning pancreatic and duodenal neuroendocrine neoplasias, a pituitary ad...
Juvenile granulosa cell tumour of the ovary presenting with hyperprolactinaemic amenorrhoea and galactorrhoea [0.03%]
绝经前妇女因颗粒细胞瘤引起高催乳素血症、停经和分泌乳汁而就诊卵巢 juvenile型颗粒细胞瘤病例报告
Ahmed Iqbal,Peter Novodvorsky,Alexandra Lubina-Solomon et al.
Ahmed Iqbal et al.
Secondary amenorrhoea and galactorrhoea represent a common endocrine presentation. We report a case of an oestrogen-producing juvenile granulosa cell tumour (JGCT) of the ovary in a 16-year-old post-pubertal woman with hyperprolactinaemia a...
Lipoid congenital adrenal hyperplasia due to STAR mutations in a Caucasian patient [0.03%]
STAR突变导致的非典型脂样先天性肾上腺皮质增生症1例报告
Jasmeet Kaur,Luis Casas,Himangshu S Bose
Jasmeet Kaur
Lipoid congenital adrenal hyperplasia (lipoid CAH), the most severe form of CAH, is most commonly caused by mutations in steroidogenic acute regulatory protein (STAR), which is required for the movement of cholesterol from the outer to the ...
A novel immunopathological association of IgG4-RD and vasculitis with Hashimoto's thyroiditis [0.03%]
IgG4相关疾病和血管炎与桥本甲状腺炎的免疫病理新联系
Hiroto Minamino,Hidefumi Inaba,Hiroyuki Ariyasu et al.
Hiroto Minamino et al.
A 73-year-old man with Hashimoto's thyroiditis (HT) suffered from purpura on the lower legs. He was diagnosed with IgG4-related disease (IgG4-RD) with serum IgG4 elevation and dacryo-sialadenitis confirmed histologically. Serum Th2 and Treg...
Autoimmune alternating hyper- and hypo-thyroidism: a rare condition in pediatrics [0.03%]
儿童中罕见的自身免疫性甲亢和甲减交替症
Luísa Correia Martins,Ana Rita Coutinho,Mónica Jerónimo et al.
Luísa Correia Martins et al.
Alternating between hyper- and hypo-thyroidism may be explained by the simultaneous presence of both types of TSH receptor autoantibodies (TRAbs) - thyroid stimulating autoantibodies (TSAbs) and TSH blocking autoantibodies (TBAbs). It is a ...
pNET co-secreting GHRH and calcitonin: ex vivo hormonal studies in human pituitary cells [0.03%]
人脑垂体细胞体外激素研究联合分泌GHRH和降钙素的pNET肿瘤模型
Taiba Zornitzki,Hadara Rubinfeld,Lyudmila Lysyy et al.
Taiba Zornitzki et al.
Acromegaly due to ectopic GHRH secretion from a neuroendocrine tumor (NET) is rare and comprises
Reversal of severe cognitive impairment following medical treatment of cystic invasive giant prolactinoma [0.03%]
药物治疗后侵袭性巨大泌乳素瘤患者的严重认知障碍逆转
J Bukowczan,K Lois,M Mathiopoulou et al.
J Bukowczan et al.
Giant prolactinomas are rare tumours of the pituitary, which typically exceed 40 mm in their largest dimension. Impairment of higher cognitive function has been noted post-operatively after transcranial surgery and as a long-term consequenc...