Combination therapy of pasireotide and pegvisomant for aggressive acromegaly with an immature PIT1-lineage PitNET [0.03%]
用于治疗具有不成熟PIT1谱系垂体神经内分泌肿瘤(PitNET)的侵袭性肢端肥大症的帕西罗肽和培维索omers组合疗法
Keiko Tomiyama,Izumi Fukuda,Shigeyuki Tahara et al.
Keiko Tomiyama et al.
Summary: A 29-year-old male presented with central scotoma and was suspected of having acromegaly based on enlargement of facial features and extremities. Serum growth hormone (GH) and insulin-like growth factor 1 (IGF-1)...
Multivessel spontaneous coronary artery dissection in a young woman using cabergoline [0.03%]
卡麦角林致年轻女性冠状动脉多支自发性夹层病変一例报告
Rachel Byrne,Paul Shiels,Rajesh Kumar
Rachel Byrne
Summary: We present a unique case of multivessel spontaneous coronary artery dissection (SCAD) in a young woman using cabergoline. This woman presented with an acute coronary syndrome (ACS) on a background of cabergoline ...
Differential reversibility of anterior and posterior pituitary dysfunction in delayed recurrent pediatric Rathke's cleft cyst [0.03%]
延迟复发的儿科拉克氏囊肿垂体前叶和后叶功能可逆性差异的研究
Atsuko Ogasawara,Shozo Yamada,Go Matsuoka
Atsuko Ogasawara
Summary: Rathke's cleft cyst (RCC) is a benign sellar or suprasellar lesion increasingly detected by magnetic resonance imaging (MRI). Although surgery is indicated for symptomatic or enlarging RCCs, recurrence may occur ...
Longitudinal evaluation of recurrent thyrotoxicosis in a single patient across four pregnancies: a case report and literature review [0.03%]
一例患者四个妊娠期毒性甲状腺肿复发的纵向评估：病例报告和文献回顾
Yosuke Kaido,Hiroto Minamino,Hidefumi Inaba et al.
Yosuke Kaido et al.
Summary: We report the case of a 37-year-old woman who presented with hyperemesis gravidarum at 11 weeks of gestation. Laboratory examination revealed severe thyrotoxicosis (TSH:
Experiences with the use of asfotase alfa in three patients with childhood-onset hypophosphatasia [0.03%]
三例以儿童期起病的低磷性佝偻病患者应用阿法骨化醇治疗的经验
Francesca Pigliaru,Davide Noto,Maria Luisa Brandi
Francesca Pigliaru
Summary: Hypophosphatasia (HPP) is a rare inherited metabolic disorder characterized by deficient activity of serum alkaline phosphatase due to loss-of-function mutations in the ALPL gene. Diagnosis confirmation, manageme...
Reactivation after total thyroidectomy? A thyroid eye disease case that challenges established clinical paradigms [0.03%]
甲状腺全切后甲状腺相关性眼病的复发？一个对传统临床思维提出挑战的眼病病例
Alejandra Niño Alarcón,Diana Cristina Henao,Leonardo Rojas et al.
Alejandra Niño Alarcón et al.
Summary: Thyroid eye disease (TED) is the most common extrathyroidal manifestation of Graves' disease, with an incidence of approximately 1.9 cases per 10,000 inhabitants per year. Its pathophysiology involves an autoimmu...
Recognising pituitary and thyroid dysfunction after craniospinal radiotherapy: an underrecognised mixed endocrine toxicity [0.03%]
颅脊放疗后垂体和甲状腺功能障碍的识别：一种被忽视的混合内分泌毒性反应
Katrien Slabbynck,Stijn Roels,Katrien Erven et al.
Katrien Slabbynck et al.
Summary: Adult medulloblastoma is a rare cerebellar tumour with an incidence of 0.6-1 per million per year in post-pubertal patients. Craniospinal radiotherapy is a key component of treatment. Endocrine organs commonly in...
IGF-2-mediated hypoglycemia in a patient with a phyllodes tumor of the breast: a rare presentation of non-islet cell tumor hypoglycemia [0.03%]
乳腺叶状肿瘤患者出现的胰岛素样生长因子-2介导的低血糖：非胰岛细胞瘤性低血糖罕见表现病例报告
Dhana Jaafar,Mohammad Bakhutma,Laurel Walfish et al.
Dhana Jaafar et al.
Summary: Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome typically associated with mesenchymal or epithelial tumors that secrete insulin-like growth factor 2 (IGF-2). Breast tumors are an unusu...
Pheochromocytoma and primary hyperparathyroidism: a very rare association in a neurofibromatosis type 1 patient unmasked by Takotsubo syndrome [0.03%]
神经纤维瘤病1型患者并发特拉佐普洛综合征后解谜的原发性嗜铬细胞瘤和原发性甲状旁腺功能亢进症极为罕见的关联症状
Nuno Faria,Valentim Lopes,Tamara Pereira et al.
Nuno Faria et al.
Summary: Neurofibromatosis type 1 is an autosomal dominant disease characterized by cutaneous, bone, and neurocognitive manifestations and an increased risk of neoplasms - more frequently cutaneous neurofibromas and optic...
Use of PRRT and osilodrostat for ectopic Cushing syndrome secondary to thymic neuroendocrine neoplasm [0.03%]
用于治疗由胸腺神经内分泌肿瘤引起的异位库欣综合征的PRLT和Osilodrostat的应用
Monica Majumder,Stephen Clarke,Elizabeth Bernard et al.
Monica Majumder et al.
Summary: We present a case of recurrent thymic neuroendocrine neoplasm (NEN) in a 43-year-old male, who developed ectopic Cushing syndrome (CS), 8 years after his initial diagnosis. Due to persistent biochemical hypercort...