Jamilah Saleh Alyami,Wael Mohammad Almistehi,Khalid Ibrahim Alkanhal
Jamilah Saleh Alyami
Summary: Webb-Dattani syndrome (WEDAS) is an extremely rare autosomal recessive disorder caused by pathogenic variants in the ARNT2 gene. It is characterized by a triad of congenital hypopituitarism, structural brain abno...
IGF-II-secreting bladder tumour presenting as a fall in a 91-year-old [0.03%]
一名91岁老人跌倒后发现患有分泌IGF-II膀胱肿瘤
Imaan Hirji,Shwetha Sairam,Hiro Khoshnaw
Imaan Hirji
Summary: Insulin-like growth factor II (IGF-II)-secreting tumours represent a subset of non-islet cell tumours and are a rare but potentially life-threatening cause of paraneoplastic hypoglycaemia. They are predominantly ...
Arina Nikolaeva,Martin Vandeputte
Arina Nikolaeva
Summary: Semaglutide, a GLP-1 receptor agonist (RA), is approved for the treatment of type 2 diabetes and obesity. However, its increasing off-label use, particularly for cosmetic weight loss, raises concerns considering ...
S Mekni,H Khiari,S Bouali et al.
S Mekni et al.
Summary: Giant cystic prolactinomas are extremely rare, with only four cases previously reported in the literature. Herein, we report the case of a 59-year-old male who presented with an acute decline in visual acuity. An...
Serena Chong,Christopher A Muir
Serena Chong
Summary: We report a 27-year-old male with a rare chromosomal anomaly involving a ring Y chromosome (RCY). Our patient presented with severe oligozoospermia in the absence of other overt phenotypic abnormalities and was u...
Shinjan Patra,Abhishek Choube,Chandrakant Munjewar et al.
Shinjan Patra et al.
Summary: A 55-year-old woman presented with ill-defined right abdominal pain and, on evaluation, was diagnosed to have a large right adrenal mass (9.5×8.5×8.7 cm). Although normotensive, she had markedly increased plasm...
Darshi Cheruvu,Eleanor White,Sarah J Glastras
Darshi Cheruvu
Summary: This is a case of a patient with a 10-year history of Cushing's disease (CD) that was previously treated with transsphenoidal pituitary tumour resection. Conception occurred spontaneously, and during early pregna...
An unusual presentation of longstanding atrophic Hashimoto's thyroiditis: challenges in a resource-limited setting [0.03%]
长期萎缩性桥本甲状腺炎的不寻常表现：资源有限条件下的挑战
Phoebe Wamalwa,Prisca Amolo
Phoebe Wamalwa
Summary: Hypothyroidism, affecting approximately 5% of the population, often remains undiagnosed, more so in developing countries. We report a 12-year-old girl with longstanding, untreated hypothyroidism who initially pre...
Posaconazole-induced primary adrenal insufficiency concomitant with pseudoaldosteronism under normal blood pressure [0.03%]
波沙康唑所致原发性肾上腺皮质功能不全合并假醛固酮症(血压正常型)
Miho Katsumata,Masaki Miura,Masahiro Masuzawa
Miho Katsumata
Summary: Several reports focus on azole-induced primary adrenal insufficiency (PAI); however, none have specifically focused on the absence of hypotension and hyperkalemia among the clinical features of adrenal insufficie...
Management of a mixed ACTH- and prolactin-secreting pituitary adenoma during pregnancy [0.03%]
垂体混合型促肾上腺皮质激素和催乳素分泌腺瘤的妊娠期管理
Astrid Le Rigoleur,Stefan Matei Constantinescu,Lina Daoud et al.
Astrid Le Rigoleur et al.
Summary: The diagnosis and management of Cushing's disease (CD) during pregnancy are challenging. Only a few cases of mixed pituitary adenomas secreting prolactin and ACTH have been reported, and none during pregnancy. We...