A rare case of apparent mineralocorticoid excess induced by chronic liquorice ingestion [0.03%]
慢性甘草摄入引起的假性盐皮质激素过多症一例报告
Aparajita Roy,Kieran Mullins
Aparajita Roy
Summary: Apparent mineralocorticoid excess (AME) syndrome is a rare condition caused by the inhibition of the renal enzyme 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2). The most common acquired cause is chronic li...
A potentially dangerous case of mistaken identity: giant asymptomatic composite phaeochromocytoma [0.03%]
一个潜在的危险误诊病例：巨大无症状混合型嗜铬细胞瘤
Annabelle G Hayes,Morton G Burt
Annabelle G Hayes
Summary: Small clinically silent phaeochromocytoma (PCC) can be identified in modern clinical practice as apparent adrenal incidentaloma or during screening of patients with familial tumour syndromes. Composite tumours co...
Diffuse thyroid enlargement and its regression in methotrexate-associated lymphoproliferative disorder: an ultrasonographic observation [0.03%]
甲氨蝶呤相关淋巴细胞增生性疾病中的弥漫性甲状腺肿大及消退：一项超声观察结果
Shingo Murasawa,Fumiya Isozaki,Shinobu Takayasu et al.
Shingo Murasawa et al.
Summary: A 70-year-old woman with Hashimoto thyroiditis, treated with levothyroxine, was diagnosed with rheumatoid arthritis 1 year prior and subsequently began methotrexate (MTX) therapy. She presented with a 2-week hist...
Acute rectal calcinosis following parathyroidectomy in a patient with primary hyperparathyroidism and preoperative hypercalcaemic crisis [0.03%]
甲状旁腺功能亢进症患者术后急性直肠钙沉着症及相关术前高血钙危象的病例报告
Helēna Apele,Dace Seisuma
Helēna Apele
Summary: This case highlights a potentially underrecognised complication - acute rectal calcinosis with ulceration in the context of parathyroidectomy due to primary hyperparathyroidism (PHPT), which is a common endocrine...
Jamilah Saleh Alyami,Wael Mohammad Almistehi,Khalid Ibrahim Alkanhal
Jamilah Saleh Alyami
Summary: Webb-Dattani syndrome (WEDAS) is an extremely rare autosomal recessive disorder caused by pathogenic variants in the ARNT2 gene. It is characterized by a triad of congenital hypopituitarism, structural brain abno...
IGF-II-secreting bladder tumour presenting as a fall in a 91-year-old [0.03%]
一名91岁老人跌倒后发现患有分泌IGF-II膀胱肿瘤
Imaan Hirji,Shwetha Sairam,Hiro Khoshnaw
Imaan Hirji
Summary: Insulin-like growth factor II (IGF-II)-secreting tumours represent a subset of non-islet cell tumours and are a rare but potentially life-threatening cause of paraneoplastic hypoglycaemia. They are predominantly ...
Arina Nikolaeva,Martin Vandeputte
Arina Nikolaeva
Summary: Semaglutide, a GLP-1 receptor agonist (RA), is approved for the treatment of type 2 diabetes and obesity. However, its increasing off-label use, particularly for cosmetic weight loss, raises concerns considering ...
S Mekni,H Khiari,S Bouali et al.
S Mekni et al.
Summary: Giant cystic prolactinomas are extremely rare, with only four cases previously reported in the literature. Herein, we report the case of a 59-year-old male who presented with an acute decline in visual acuity. An...
Serena Chong,Christopher A Muir
Serena Chong
Summary: We report a 27-year-old male with a rare chromosomal anomaly involving a ring Y chromosome (RCY). Our patient presented with severe oligozoospermia in the absence of other overt phenotypic abnormalities and was u...
Shinjan Patra,Abhishek Choube,Chandrakant Munjewar et al.
Shinjan Patra et al.
Summary: A 55-year-old woman presented with ill-defined right abdominal pain and, on evaluation, was diagnosed to have a large right adrenal mass (9.5×8.5×8.7 cm). Although normotensive, she had markedly increased plasm...