Risk factors for nosocomial meningitis in patients with external ventricular drainages [0.03%]
脑室外引流患者的医院内脑膜炎危险因素分析
Coline Raffenot,Vincent Doat-Sarfati,François Antonini et al.
Coline Raffenot et al.
Background: External ventricular drain (EVD)-associated infections are a significant cause of morbidity and mortality. Nosocomial meningitis (NM) poses diagnostic challenges, and its prognosis heavily relies on the timely...
Heat stress-induced mitochondrial damage and its impact on leukocyte function [0.03%]
热应力引起的线粒体损伤及其对白细胞功能的影响
Toshiaki Iba,Julie Helms,Isao Nagaoka et al.
Toshiaki Iba et al.
Heatstroke is characterized by systemic inflammation, immune dysregulation, and multiorgan failure, in which mitochondrial damage in leukocytes plays a pivotal role. This review examines the mechanisms by which heat stress induces leukocyte...
UNLOADERS-PVAD Weaning Score: predicting post-weaning adverse events in cardiogenic shock patients supported by microaxial flow pump [0.03%]
UNLOADERS-PVAD拔管评分：预测心源性休克经微轴流泵辅助患者撤机后不良事件的风险
Yuki Ikeda,Keita Saku,Jun Nakata et al.
Yuki Ikeda et al.
Background: Limited data are available on risk stratification in patients undergoing weaning from percutaneous ventricular assist devices (PVADs). We aimed to identify factors associated with adverse events following PVAD...
Effects of a multicomponent sleep enhancement protocol on delirium incidence in elderly critically ill surgical patients: a randomized controlled trial [0.03%]
多组件睡眠增强方案对老年重症外科患者谵妄发生率影响的随机对照试验
Nuanprae Kitisin,Suchanun Lao-Amornphunkul,Nattachai Hemtanon et al.
Nuanprae Kitisin et al.
Background: Sleep disturbances are common in critically ill patients and increase delirium risk, leading to worse outcomes. Non-pharmacologic sleep interventions show mixed results, with limited randomized controlled tria...
PEEP-AKI-COVID ICU: Effect of positive end-expiratory pressure on acute kidney injury development in patients with COVID-19-associated acute respiratory distress syndrome: an ancillary analysis of the COVID-ICU study [0.03%]
新冠相关急性呼吸窘迫综合征患者的肾脏替代治疗对呼气末正压的反应：来自COVID-ICU研究的事后分析
Léo Poirot,Lionel Tchatat Wangueu,Isaure Breteau et al.
Léo Poirot et al.
Background: Acute Kidney Injury (AKI) is common in patients admitted to the intensive care unit (ICU) for severe SARS-CoV-2 pneumonia and is associated with a worse prognosis. Mechanical ventilation has been identified as...
Effect of early intubation on patient-centered outcomes in urosepsis: a retrospective multicenter cohort study [0.03%]
早期气管插管对泌尿系感染性休克患者预后影响的回顾性多中心队列研究
Masafumi Suga,Ryan Ling,Sho Katsuragawa et al.
Masafumi Suga et al.
Background: Urosepsis has a reported mortality rate of up to 13.5%, and approximately 38% of affected patients require intubation. This study evaluated the association between the timing of intubation and in-hospital mort...
Association between early administration of mucoactive agents and in-hospital mortality in patients with pneumonia requiring mechanical ventilation: a nationwide cohort study [0.03%]
早期应用化痰药物与肺炎机械通气患者的院内死亡率的关联：一项全国队列研究
Akira Sasaki,Mikio Nakajima,Tomohiro Shinozaki et al.
Akira Sasaki et al.
Background: In patients with pneumonia requiring mechanical ventilation, increased airway secretions are associated with prolonged mechanical ventilation, but the effect of mucoactive agents remains unclear. The present s...
Granulomonocytapheresis for chronic inflammatory diseases and sepsis [0.03%]
粒细胞-单核细胞pheresis治疗慢性炎症性疾病和脓毒症
Toshiaki Iba,Hideshi Okada,Takahiro Miki et al.
Toshiaki Iba et al.
Granulomonocytapheresis (GMA) has long been used to treat refractory chronic inflammatory diseases. Recently, an exploratory clinical study showed that GMA was effective for sepsis, and its use has been approved in Japan. The purpose of thi...
Strategies for discontinuing vasopressin and norepinephrine during the recovery phase of shock: a single-center retrospective study [0.03%]
休克恢复期停用血管加压素及去甲肾上腺素的策略：单中心回顾性研究
Shiho Suganuma,Shigehiko Uchino,Seiya Nishiyama et al.
Shiho Suganuma et al.
Background: The optimal strategy for discontinuing arginine vasopressin and norepinephrine in patients recovering from shock remains uncertain. Although prior studies have suggested a higher risk of hypotension when argin...
Expert consensus statement on the evaluation, treatment, and transfer of cardiogenic shock using a Delphi method approach: a report of the Japan Critical Care Cardiology Committee (J4 CS) [0.03%]
日本危重病态心脏病委员会关于使用德尔菲方法评估心源性休克的治疗和转诊的专家共识声明（J4 CS报告）
Takahiro Nakashima,Toru Kondo,Jun Nakata et al.
Takahiro Nakashima et al.