Inhaled nitric oxide for acute respiratory distress syndrome in adults: a systematic review and meta-analysis [0.03%]
成人急性呼吸窘迫综合征吸入一氧化氮治疗的系统评价和meta分析
Yuta Nakamura,Yuki Kotani,Takatoshi Koroki et al.
Yuta Nakamura et al.
Background: Although inhaled nitric oxide (iNO) is used as a rescue therapy in patients with acute respiratory distress syndrome (ARDS), its impact on patient-centered outcomes remains uncertain. To address this gap, we c...
Discrepancy in perceived appropriate and desired resuscitation durations between physicians and laypersons in cardiac arrest patients [0.03%]
医务人员与普通民众对心脏骤停患者心肺复苏适宜时间和期望时间认知差异的研究
Yuko Tanabe,Takeshi Namba,Shoichi Maeda et al.
Yuko Tanabe et al.
This study examined a discrepancy that exists between the duration of resuscitative efforts that physicians perceive as appropriate and the duration that laypersons desire. We conducted an online nationwide cross-sectional survey with 323 p...
Age-related epidemiology and outcomes of sepsis in Japanese critical care units: a nationwide administrative claims database study [0.03%]
日本重症监护单元的脓毒症年龄相关流行病学和预后：全国行政索赔数据库研究
Hirotada Kobayashi,Mayuko Tonai,Toshiyuki Karumai et al.
Hirotada Kobayashi et al.
Background: The global rise in the elderly population presents unique challenges in intensive care, including treatment decisions and end-of-life care due to physiological, ethical, and social complexities. However, data ...
Anxiety, depression and distress in family members of people who have experienced a critical care admission: a systematic review and Bayesian meta-analysis [0.03%]
家属成员焦虑、抑郁和压力的系统性回顾及bayesian元分析
P Hartley,C Brown,V Danesh et al.
P Hartley et al.
Background: Family members of adults who experience a critical care admission often experience significant strain and emotional distress following discharge. This meta-analysis aimed to synthesise the levels of distress, ...
Prolonged infusion of remimazolam in surgical and medical intensive care unit patients: a pilot pharmacokinetic study [0.03%]
手术和医学重症监护室患者注射右美托咪啶的药代动力学研究（一项试点研究）
Yuji Suzuki,Matsuyuki Doi,Yoshitaka Aoki et al.
Yuji Suzuki et al.
Background: The pharmacokinetics of prolonged remimazolam infusion in patients undergoing long-term mechanical ventilation remain unclear. This study aimed to evaluate the pharmacokinetics of remimazolam administered cont...
Development and validation of the Hypotensive Exposure Duration Index for mortality risk prediction in critically ill patients [0.03%]
用于预测重症患者死亡风险的低血压暴露持续时间指数的开发与验证
Xiao-Yan Ding,Hai-Ping Xu,Jing-Ru Zhang et al.
Xiao-Yan Ding et al.
Background: Blood pressure management is crucial in critical care, but relationships between pressure patterns and outcomes remain incompletely understood. We analyzed minute-by-minute blood pressure data to develop and v...
Predictors of and hospital-level variation in intensive care unit readmissions in Japan: a nationwide inpatient database study [0.03%]
日本重症监护病房再入院的预测因素及医院间的差异：来自全国住院病人数据库的研究
Hiroyuki Ohbe,Yusuke Sasabuchi,Yuya Kimura et al.
Hiroyuki Ohbe et al.
Background: Intensive care unit (ICU) readmission is a widely recognized marker of patient outcomes and organizational performance. Early ICU readmission-commonly defined as a return to the ICU within 48 h or 2 full calen...
Management of endothelial dysfunction in septic shock: role of albumin administration [0.03%]
脓毒症休克内皮功能障碍的防治：白蛋白治疗的作用
Ignacio Martin-Loeches,Alejandro Rodríguez,Lene Russell et al.
Ignacio Martin-Loeches et al.
Sepsis is a significant global health issue, with high morbidity, mortality, and economic burden. Its definition has evolved, with the latest Sepsis-3 criteria emphasizing life-threatening organ dysfunction due to a dysregulated host respon...
TIGRIS and EUPHRATES eventually join and provide new evidence: a narrative review of the polymyxin B hemoperfusion [0.03%]
底格里斯河和幼发拉底河最终汇合提供新的证据：头孢他啶/阿维巴坦治疗碳青霉烯类耐药肠杆菌科细菌感染的系统评价和网络 meta 分析
Toshiaki Iba,Julie Helms,Isao Nagaoka et al.
Toshiaki Iba et al.
Septic shock driven by endotoxemia is associated with high mortality despite advances in supportive care. Polymyxin B hemoperfusion (PMX-HP) selectively removes circulating endotoxin and has shown variable efficacy in randomized trials. Whi...
Development and validation of the STeP score for predicting tracheostomy in patients with sepsis using a nationwide ICU database: a retrospective observational study [0.03%]
利用全国重症监护病房数据库预测脓毒症患者气管切开的STEPS积分开发与验证：回顾性观察研究
Kazuya Kikutani,Mitsuaki Nishikimi,Michihito Kyo et al.
Kazuya Kikutani et al.
Background: Among patients with sepsis admitted to the intensive care unit (ICU), a substantial proportion require mechanical ventilation, and a subset eventually undergo tracheostomy. Early identification of patients at ...