Survival of patients with KRAS wild-type metastatic colorectal cancer is identical after sequential treatment with cetuximab and bevacizumab regardless of the sequence - A retrospective single-center study [0.03%]
西妥昔单抗和贝伐单抗序贯治疗KRAS野生型转移性结直肠癌患者的研究：一项基于单中心的回顾性研究
Yanhong Deng,Yue Cai,Jiayu Lin et al.
Yanhong Deng et al.
Objective: To investigate the overall survival of patients with KRAS wild-type metastatic colorectal cancer (mCRC) after sequentially receiving both bevacizumab and cetuximab during the course of treatment. ...
Radiographical findings in patients with liver cirrhosis and hepatic encephalopathy [0.03%]
肝硬化和肝性脑病患者的放射学检查结果
Saleh Elwir,Hassan Hal,Joshua Veith et al.
Saleh Elwir et al.
Background and aims: Hepatic encephalopathy is a common complication encountered in patients with liver cirrhosis. Hepatic encephalopathy is not reflected in the current liver transplant allocation system. Correlation was...
Perceptions of non-alcoholic fatty liver disease - an Asian community-based study [0.03%]
非酒精性脂肪肝病的感知状况——一项基于亚洲社区的研究
George B B Goh,Clarence Kwan,Sze Ying Lim et al.
George B B Goh et al.
Background and aims: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is closely related to metabolic syndrome and its risk factors. Worldwide, epidemiological studies have reported N...
Loreen März,Pompiliu Piso
Loreen März
Peritoneal seedings of a colorectal tumor represent the second most frequent site of metastasis (after the liver). In the era of 5-fluorouracil (5-FU)-only chemotherapy, the prognosis was poor for colorectal cancer with peritoneal metastase...
The case of the missing appendix: a case report of appendiceal intussusception at the site of colonic mullerianosis [0.03%]
误诊为阑尾缺失的一例结肠穆勒氏瘤并回肠套叠病例报告
Federico P Quirante,Lisandro M Montorfano,Federico Serrot et al.
Federico P Quirante et al.
Right lower quadrant pain is a symptom with an exceptionally broad differential diagnosis. Intussusception of the appendix is a very uncommon condition with many manifestations. Additionally, the pathologic finding of ectopic presence of a ...
The 2 + 1 paradigm: an efficient algorithm for central reading of Mayo endoscopic subscores in global multicenter phase 3 ulcerative colitis clinical trials [0.03%]
2+1模式：一项针对全球多中心溃疡性结肠炎三期临床试验中梅奥内镜评分集中阅片的高效算法
Harris A Ahmad,Klaus Gottlieb,Fez Hussain
Harris A Ahmad
Despite its importance and potential impact in clinical trials, central reading continues to be an under-represented topic in the literature about inflammatory bowel disease (IBD) clinical trials. Although several IBD studies have incorpora...
Extra-hepatic manifestations associated with hepatitis E virus infection: a comprehensive review of the literature [0.03%]
与HEV感染相关的肝外表现：文献综述
Fateh Bazerbachi,Samir Haffar,Sushil K Garg et al.
Fateh Bazerbachi et al.
Background and aims: Hepatitis E virus (HEV) infection is a significant public health problem that afflicts almost 20 million individuals annually and causes acute liver injury in 3.5 million, with approximately 56 000 de...
Molecular phenotypes of colorectal cancer and potential clinical applications [0.03%]
结直肠癌分子分型及临床应用前景
Jonathan M Kocarnik,Stacey Shiovitz,Amanda I Phipps
Jonathan M Kocarnik
Colorectal cancer (CRC) is a heterogeneous disease, arising from many possible etiological pathways. This heterogeneity can have important implications for CRC prognosis and clinical management. Epidemiological studies of CRC risk and progn...
Hyperbaric oxygen therapy for chronic antibiotic-refractory ischemic pouchitis [0.03%]
高压氧治疗慢性抗生素耐药性缺血性袋炎
Custon T Nyabanga,Geeta Kulkarni,Bo Shen
Custon T Nyabanga
Hyperbaric oxygen therapy (HBOT) has been shown to be efficacious in treating various conditions, including perianal Crohn's disease. Here we present a case of a 59-year-old male with a history of ulcerative colitis, who underwent a total p...
An uncommon source of upper gastrointestinal bleeding: epiphrenic esophageal diverticulum [0.03%]
上消化道出血的少见病因：食管膈上憩室
Chung Sang Tse,Neil D Parikh
Chung Sang Tse
Esophageal diverticula are rare findings that have an estimated incidence of 1 per 500 000 people per year, even though acute upper gastrointestinal bleeding is a relatively common medical emergency with an incidence of up to 150 per 100 00...