Single-cell transcriptomic landscape indicates the potential role of immunotherapy in metastatic pancreatic angiosarcoma [0.03%]
单细胞转录组分析揭示了免疫治疗在转移性胰腺血管肉瘤中的潜在作用
Yizhen Yang,Luohai Chen,Man Liu et al.
Yizhen Yang et al.
Background: Pancreatic angiosarcoma is a rare and highly aggressive tumor originating from lymphatic or vascular endothelial cells, with poor prognosis and few effective treatments. In this study, we aimed to characterize...
The role of exome data reanalysis in clarifying STXBP3 associated inflammatory bowel disease and hearing loss [0.03%]
外显子组数据再分析在阐明STXBP3相关肠炎和听力损失中的作用
Lukáš Ryba,Tereza Lerchová,Jiří Bronský et al.
Lukáš Ryba et al.
Metabolic dysfunction-associated steatotic liver disease is associated with the risk of severe liver fibrosis in pediatric population [0.03%]
与儿童人群严重肝纤维化风险相关的代谢紊乱相关脂肪性肝病
Wei Li,Lina Jiang,Meiling Li et al.
Wei Li et al.
Metabolic dysfunction-associated steatotic liver disease (MASLD) has been proposed to replace the term of non-alcoholic fatty liver disease (NAFLD). To investigate the effect of MASLD on liver fibrosis and validate the clinical utility of M...
Incidence trends and disparities in infection-related malignancies of the liver among US adults, 2000-2019 [0.03%]
2000至2019年美国成人肝感染相关恶性肿瘤的发病率趋势及差异研究
Zhihui Zou,Xue Wang,Bing Huang et al.
Zhihui Zou et al.
Background: Trend analysis in infection-related malignancy of the liver is still limited. We aimed to evaluate the incidence trend in hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (iCCA), combined hepato...
Pressurized intraperitoneal aerosol chemotherapy in advanced gastric cancer with peritoneal metastases: a comprehensive meta-analysis of feasibility, efficacy, and safety [0.03%]
晚期胃癌腹膜转移患者行腹腔镜上压注化疗的可行性和安全性综合meta分析研究
Ruijian Chen,Zifeng Yang,Renjie Li et al.
Ruijian Chen et al.
Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has emerged as a promising therapeutic approach for treating advanced gastric cancer with peritoneal metastases. Herein, we conducted this meta-analysis to evaluate the feasibility, e...
Association of maternal smoking, breastfeeding, and multiple birth with irritable bowel syndrome in older adults: a UK Biobank cohort study [0.03%]
一项英国生物银行队列研究：关于母亲吸烟、母乳喂养和多胎与老年人肠易激综合征的关系
Xinyang Liu,Ruilang Lin,Xinyue Li et al.
Xinyang Liu et al.
Background: We aimed to investigate associations between three perinatal early-life factors and the risk of irritable bowel syndrome (IBS) in middle-aged and elderly people by using data from UK Biobank. ...
Natchaya Polpichai,Chongkonrat Maneenil,Pojsakorn Danpanichkul et al.
Natchaya Polpichai et al.
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide, particularly among individuals with chronic liver diseases. Early detection through surveillance significantly improves survival rates and current...
Efficacy of the modified parallel method combined with the double-guide-wire technique for safer endoscopic ultrasound-guided hepaticogastrostomy [0.03%]
改良平行法联合双导丝技术内镜超声引导下胆管胃肠吻合的疗效分析
Koichiro Mandai,Takato Inoue
Koichiro Mandai
Clinical-radiomics models with machine-learning algorithms to distinguish uncomplicated from complicated acute appendicitis in adults: a multiphase multicenter cohort study [0.03%]
基于机器学习算法的临床影像组学模型鉴别成人单纯性和复杂性急性阑尾炎的多中心队列研究
Li Li,Yangyang Sun,Yang Sun et al.
Li Li et al.
Increasing evidence suggests that non-operative management (NOM) with antibiotics could serve as a safe alternative to surgery for the treatment of uncomplicated acute appendicitis (AA). However, accurately differentiating between uncomplic...
Long-term exposure to constant light disrupts intestinal stem cells through sympathoexcitation-induced Wnt5a signaling inhibition [0.03%]
长期暴露于持续光照通过交感神经过度兴奋抑制Wnt5a信号通路扰乱肠道干细胞
Yu-Wan Wang,Qin-Yao Li,Ling-Feng Liu et al.
Yu-Wan Wang et al.
Background: Long-term exposure to constant light is becoming a prevalent lifestyle that is associated with irritable bowel syndrome (IBS), a chronic functional gastrointestinal disorder. Intestinal stem cells (ISCs) are a...