Evaluation of [18F]MK-6240 binding to tau protein in postmortem human brains of Down syndrome and Alzheimer's disease and assessment of off-target (non-tau) binding [0.03%]
Fariha Karim,Agnes P Biju,Christopher Liang et al.
Fariha Karim et al.
Single cell protein profiling of focal cortical dysplasia in a patient requiring multiple resections [0.03%]
Nada A Elsayed,Robert P Naftel,Bret C Mobley et al.
Nada A Elsayed et al.
Low-grade peripheral inflammation accelerates retinal amyloid pathology and dysfunction in an Alzheimer's disease mouse model [0.03%]
低水平外周炎症可加速阿尔茨海默病小鼠模型的视网膜淀粉样蛋白病理变化和功能障碍
Lien Cools,Yasmin Dahdouh-Guebas,Iene Kemps et al.
Lien Cools et al.
Effects of chemogenetic inhibition of serotonergic raphe-striatal neurons on L-DOPA-induced behaviors and neurochemistry in a rat model of Parkinson's disease [0.03%]
化学遗传抑制血清素能背缝纹状体神经元对帕金森病大鼠模型左旋多巴诱导的行为和神经化学的影响
Carla N Budrow,Luis-Daniel Bernal-Conde,Ivette M Sandoval et al.
Carla N Budrow et al.
Erika Kitajima,Ashley Suwanda,Dan Jobson et al.
Erika Kitajima et al.
Carotid artery disease (CAD) is a recognised cause of stroke. However, the relationships between CAD, cerebral small vessel disease (SVD) and dementia remain unclear. We hypothesised that CAD in older individuals contributes to cerebral SVD...
microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer's disease patients [0.03%]
微小核糖核酸-132通过阿尔茨海默病患者诱导多能干细胞来源的小胶质细胞的炎症反应发挥神经保护作用
Amber Penning,Sarah Snoeck,Olmo Ruiz Ormaechea et al.
Amber Penning et al.
Prognostic stratification of chordoid meningiomas: the role of chromosome 1p/22q Loss [0.03%]
染色体1p/22q缺失在脑膜瘤预后分层中的作用
Rosina Paterra,Matteo Zago,Fabio Agistri et al.
Rosina Paterra et al.
Translation of expanded CGG repeats in LRP12 associated oculopharyngodistal myopathy [0.03%]
LRP12基因的CGG重复序列扩展突变与眼咽远端肌病相关性研究
Chengcheng Li,Jil A Daw,Sara K Pittman et al.
Chengcheng Li et al.
Oculopharyngodistal myopathy (OPDM) is characterized by ptosis, ophthalmoparesis, dysphagia, and distal weakness. Myopathological features include rimmed vacuoles and intranuclear inclusions. OPDM is associated with a pathogenic CGG repeat ...
Small molecule modulation of the p75 neurotrophin receptor promotes dendritic spine resilience to pathogenic tau species and reduces their accumulation [0.03%]
小分子调节p75神经营养素受体促进突触棘抵抗病理性tau蛋白，并减少其积累
Tao Yang,Yeonglong Ay,Sukhneet Kaur et al.
Tao Yang et al.
Clinicopathologic, molecular and tumor immune microenvironment features of mismatch repair-deficient glioblastomas in Lynch syndrome: a multicenter study of 29 cases with therapeutic implications [0.03%]
错配修复缺陷型胶质母细胞瘤的临床病理、分子和肿瘤免疫微环境特征：利克综合症中29例患者的多中心研究及治疗意义
Zhi-Gang Yao,Xue-Long Li,Wen-Juan Wen et al.
Zhi-Gang Yao et al.
Glioblastoma (GBM) is a relatively rare manifestation of Lynch syndrome (LS), and its defining characteristics are not yet fully defined. This study employs an integrated analysis of the clinicopathological, molecular, and tumor immune micr...