Durable heparin/zwitterion composite coatings for enhanced hemocompatibility and antibacterial performance [0.03%]
用于改善血液相容性和抗菌性能的耐用肝素/两性离子复合涂层
Haihua Wang,Na Li,Chaoxian Chen et al.
Haihua Wang et al.
The effectiveness of surface coatings for blood-contacting medical devices is often limited by poor stability, increasing the risk of thrombosis and infection. We developed a heparin/zwitterion coating comprising an amine-rich dopamine/poly...
Natural polymer-based soft actuators: from biomass to bioapplications [0.03%]
基于天然聚合物的软执行器：从生物量到生物应用
Jiachuan Hua,Qilong Zhao,Xuemin Du
Jiachuan Hua
Nature-inspired soft actuators constructed from polymers have been widely used in wearables, implants, and soft robotics. Despite remarkable progress, conventional soft actuators formed by synthetic polymers exhibit poor sustainability and ...
Rationally designed sodium thiosulfate-loaded solid lipid nanoparticles for inner ear delivery and prevention of medication-induced ototoxicity [0.03%]
理性的设计负载硫代硫酸钠的固脂纳米粒以用于耳用给药和预防药物性耳毒性
Brototi Chakrabarty,Neeraj S Thakur,Aditya D Joshi et al.
Brototi Chakrabarty et al.
Medication-induced ototoxicity (MIO) results from treatment regimens such as aminoglycosides and platinum-based drugs, leading to sensory hair cell damage in the inner ear, which is responsible for converting mechanical sound vibrations to ...
A nitric oxide-releasing organic selenium-grafted phosphorylcholine coating for thrombosis and inflammation prevention in extracorporeal membrane oxygenation [0.03%]
一种硝酸盐释放型有机硒接枝磷酸胆碱涂层用于体外膜氧合抗凝抗炎
Lietao Wang,Fanjun Zhang,Rifang Luo et al.
Lietao Wang et al.
Thrombosis and inflammation represent major challenges limiting the functionality of asymmetric poly(4-methyl-1-pentene) (PMP) hollow fiber membranes in extracorporeal membrane oxygenation (ECMO) systems. Moreover, the interplay between the...
Enhanced sonodynamic therapy and theranostic integration for breast cancer treatment: nanomaterial-driven multifunctional platforms [0.03%]
纳米材料驱动的多功能平台增强乳腺癌声动力治疗及诊疗一体化研究
Jiayi Ma,Wei Mei,Han Hu et al.
Jiayi Ma et al.
Breast cancer is a common malignant tumour affecting women worldwide. Despite advances in various treatment areas, existing methods are still limited by the disease's high heterogeneity and complexity, which makes achieving ideal therapeuti...
FLIM-guided self-reporting of PDT efficacy using a mitochondria-targeted, viscosity-sensitive quinolinium probe [0.03%]
一种线粒体靶向、粘度敏感的荧光探针引导下光动力治疗有效性的自报告系统
Youxiang Ren,Liping Su,Xuelin Tang et al.
Youxiang Ren et al.
Mitochondrial viscosity plays a pivotal role in the microenvironment of mitochondria and is closely associated with pathological conditions. As a light-activated treatment for cancer and infections, photodynamic therapy (PDT) relies on reac...
Self-assembled nanostructured antimicrobial peptides: design strategies, structures, mechanism and therapeutic applications [0.03%]
自我组装的纳米结构抗菌肽：设计策略、结构、机制和治疗应用
Zishu Wang,XianXi Li,Huijing Chen et al.
Zishu Wang et al.
Bacterial infections pose a global threat. Self-assembling antimicrobial peptides (AMPs) demonstrate remarkable biocompatibility, antibacterial efficacy, resistance to drug resistance, and stability in combating infections due to their uniq...
Antimicrobial peptide hydrogels: synthesis, ROS regulation mechanism, and multimodal therapeutic applications in drug delivery systems [0.03%]
抗菌肽水凝胶：合成、ROS调节机制及其在药物递送系统中的多模式治疗应用
Dingjun Cai,Canhong Li,Taifu Zhu et al.
Dingjun Cai et al.
Antimicrobial peptides (AMPs) are a unique class of bioactive compounds with applications in antimicrobial therapy, anti-inflammatory regulation, and drug delivery. As antibiotic resistance escalates globally, AMPs have emerged as one of th...
Bioinspired sodium alginate/silk fibroin dual-crosslinked conductive injectable hydrogel for neural stem cell therapy in cerebral palsy [0.03%]
用于脑瘫神经干细胞治疗的生物启发型钠 alginate/silk fibroin 双交联导电注射水凝胶
Simiao Yu,Chenyu Liu,Yongxin Pan et al.
Simiao Yu et al.
Cerebral palsy (CP), the leading cause of lifelong motor disability in children, lacks effective neural regeneration therapies. Current treatments only alleviate symptoms, and while neural stem cell (NSC) transplantation shows promise, its ...
Monomer exchange dynamics in ureido-pyrimidinone supramolecular polymers via molecular simulations [0.03%]
基于分子模拟的脲基-嘧啶酮超分子聚合物单体交换动力学研究
Annalisa Cardellini,Cristina Caruso,Laura Rijns et al.
Annalisa Cardellini et al.
The use of synthetic supramolecular polymers, built with monomers that self-assemble via non-covalent, reversible interactions, is rapidly growing in many fields, including energy, environmental, and bioengineering applications. Very recent...