Incorporation of NU-1000 into cellulose acetate membranes with preserved indoxyl sulfate adsorption [0.03%]
具有吸附吲哚硫酸盐功能的NU-1000载入乙酸纤维素膜
Rita F Pires,Beatriz S Nunes,Flávia S C Rodrigues et al.
Rita F Pires et al.
Zirconium-based metal-organic framework (MOF) NU-1000 was successfully synthesized and exhibited the expected structural and chemical properties, confirming its suitability as an adsorbent for protein-bound uremic toxins (PBUTs). In batch e...
A pH-responsive multifunctional sericin-pyrrole hydrogel with inherent antibacterial and antioxidant activities [0.03%]
一种具有内在抗菌和抗氧化活性的pH响应型多功能家蚕丝素-吡咯水凝胶
Weiyang Wang,Akou May Tehoungue,Zilong Gao et al.
Weiyang Wang et al.
Hydrogels derived from natural materials with intrinsic bioactivities and pH responsiveness have attracted considerable interest in biomedical applications due to their versatile functionality. In this study, a robust multifunctional serici...
Rational design of structurally rich DNA aptamer screening libraries guided by empirical sequence trends and stable loop motifs [0.03%]
基于经验序列规律和稳定发卡结构的富结构DNA适配体筛选文库的设计
Steven Ochoa,Valeria Tohver Milam
Steven Ochoa
Aptamers are typically identified by screening combinatorial libraries with random sequence populations. Structured oligonucleotide libraries which include self-folded motifs such as canonical hairpins or noncanonical G quadruplexes offer p...
Synthesis of β-aminoacrylated betulin derivatives by a spontaneous amino-yne reaction for antifungal applications [0.03%]
用于抗真菌应用的熊果素衍生物的β-氨基丙烯酸酯的自发氨炔合成
Jiahui Lin,Jing Xiang,Kaojin Wang et al.
Jiahui Lin et al.
Betulin, a lupane-based pentacyclic triterpenoid, is renowned for its sustainability and potent antifungal properties. By leveraging a spontaneous amino-yne reaction in conjunction with betulin, novel biomolecules representing a diverse lib...
Junfeng Feng,Yu Wang,Letong Huang et al.
Junfeng Feng et al.
Bacteria play dual roles as both pathogenic agents and therapeutic agents. Their inherent motility, tumor-preferential colonization, and immunomodulatory properties confer significant disease prevention and treatment potential in fields suc...
Injectable hydrogel-based localized delivery of IDO-galectin-3 mitigates neuroinflammation and promotes neuronal sparing after spinal cord contusion in rats [0.03%]
IDO-galectin-3局部递送缓释凝胶在脊髓损伤大鼠中的抗炎和促神经保护效应
Gopal Agarwal,Allison Campbell,Arun Wanchoo et al.
Gopal Agarwal et al.
Traumatic spinal cord injury (SCI) results in excessive neuroinflammation characterized by secondary injury cascades, which in turn hinders axonal regeneration and impairs functional recovery. Here, we sought to deliver an anti-inflammatory...
Ionizable mesoporous silica nanoparticle-mediated siAURKB delivery for colorectal cancer therapy [0.03%]
用于结直肠癌治疗的携带siAURKB的可解离介孔硅纳米颗粒
Yuhao Yao,Yuheng Leng,Xilong Li et al.
Yuhao Yao et al.
Colorectal cancer (CRC) is a common malignant tumor with high incidence and mortality worldwide. Conventional therapeutic strategies, such as surgical resection and chemotherapy, which result in improved outcomes for some patients, are grea...
Chen Cheng,Zihao Fu,Chi Zhang et al.
Chen Cheng et al.
Partial nephrectomy is increasingly becoming the preferred choice for early-stage renal cancer. However, the complex suturing process prolongs warm ischemia time, impairs the function of normal renal parenchyma, and often leads to complicat...
Pickering high internal phase emulsion templated poly(ε-caprolactone) scaffolds functionalized using type 1 collagen for enhanced bioactivity [0.03%]
用于增强生物活性的I型胶原修饰的Pickering高内相聚己内酯支架
Meenal Agrawal,Doyel Ghosal,Bhanu Nandan et al.
Meenal Agrawal et al.
Overcoming the limitations associated with autologous and allogeneic grafts to treat refractory bone defects, bone regeneration scaffolds have emerged as a promising alternative. In this direction, poly(ε-caprolactone) (PCL) based Pickerin...
Polysaccharide-based hydrogels for alveolar socket healing: biological functions and material design strategies [0.03%]
基于多糖的用于肺泡窝愈合的水凝胶：生物学功能和材料设计策略
Yuxuan Guo,Hongtao Hu,Bo Yang et al.
Yuxuan Guo et al.
Tooth extraction sockets undergo a tightly regulated sequence of hemostasis, inflammation, angiogenesis and bone remodeling within a confined bony cavity that is directly exposed to the oral environment. Conventional socket dressings mainly...