Trimetallic nano trap-mediated glycolytic and mitochondrial metabolism co-inhibition: ATP suppression for enhanced metal ion-interference therapy [0.03%]
三金属纳米陷阱介导的糖酵解和线粒体代谢共抑制：ATP抑制以增强金属离子干扰疗法
Qingqing Wang,Kun Yan,Lin Zhu et al.
Qingqing Wang et al.
Mitochondria serve as central regulators of tumorigenesis, progression, metastasis, and chemoresistance, playing a pivotal role in cancer bioenergetics and thus representing prime targets for anticancer therapy. However, conventional strate...
Cucumber-derived exosome-like nanovesicles encapsulating epigallocatechin gallate for skin depigmentation: molecular docking, stability, and efficacy in B16/F10 cells and zebrafish [0.03%]
一种新型EGCG纳米载体用于皮肤美白：黄瓜源类外体纳米囊泡的分子对接、稳定性和B16/F10黑色素瘤细胞及斑马鱼体内效果研究
Li Tao,Ping Wang,Mengying Zhang et al.
Li Tao et al.
To address the challenges of instability and low bioavailability that limit the application of (-)-epigallocatechin gallate (EGCG) as a whitening agent, we engineered a cucumber-derived exosome-like nanovesicle (CEV) as a synergistic nanoca...
Fabrication of a hybrid cellularized cardiac patch via 3D bioprinting of alginate-gelatin-PEOz patterns on electrospun PLCL-PEOz nanofibers [0.03%]
基于静电纺丝PLCL-PEOz纳米纤维的藻酸盐-明胶-PEOz心脏补片生物墨水的3D打印及细胞打印
Muthu Parkkavi Sekar,David Raj Chellappan,Dhakshinamoorthy Sundaramurthi et al.
Muthu Parkkavi Sekar et al.
Cellular cardiac patches for treating myocardial infarction (MI) need to exhibit both structural fidelity and functional features for their effective regeneration. To achieve a biomimetic patch, we report the development of a hybrid cellula...
Hepatocyte purification column using thermoresponsive glycopolymer-modified silica beads [0.03%]
一种使用热响应糖基聚合物修饰的硅胶珠的肝细胞纯化柱
Kenichi Nagase,Junnosuke Matsuda
Kenichi Nagase
Regenerative medicine involving hepatocytes holds promise as a therapeutic strategy for liver diseases. The clinical application of this approach requires a reliable technique for hepatocyte isolation. In this study, we developed a cell sep...
Injectable VEGF-loaded gelatin-hyaluronic acid hydrogel to synergistically promote flap survival via rapid angiogenesis [0.03%]
负载VEGF的明胶-透明质酸水凝胶促进移植皮肤瓣快速血管化及成活研究
Dan Zhong,Lin Zhi,Haitao Xiao et al.
Dan Zhong et al.
Random-pattern skin flaps are commonly used in plastic surgery to close skin defects, but necrosis often occurs in the distal portions of flaps due to insufficient blood supply, which severely limits their clinical utility. Thus, we develop...
Modulating oxidative stress and bacterial infection with carbon dot-infused bioactive hydrogels for infected wound regeneration [0.03%]
基于碳点的生物活性水凝胶调节氧化应激和细菌感染促进感染伤口愈合
Ananya Mohanty,Kushal Johri,Arindam Pramanik et al.
Ananya Mohanty et al.
Chronic non-healing wounds arise from sustained oxidative stress due to excessive reactive oxygen species (ROS) accumulation, coupled with persistent bacterial colonization. However, existing wound dressings exhibit limited capability to co...
Correction: Matrix-bound Tenascin-C directs neuronal differentiation through stiffness-tuned MeHA hydrogels mimicking the spinal cord microenvironment [0.03%]
纠正：矩阵结合的Tenascin-C通过刚度调节的MeHA水凝胶（模仿脊髓微环境）指导神经元分化
Rounak Pokharel,Vasanti Dhakate,Jessica Onyak et al.
Rounak Pokharel et al.
Correction for 'Matrix-bound Tenascin-C directs neuronal differentiation through stiffness-tuned MeHA hydrogels mimicking the spinal cord microenvironment' by Rounak Pokharel et al., J. Mater. Chem. B, 2026, https://doi.org/10.1039/d6tb0024...
Published Erratum
Journal of materials chemistry. B. 2026 May 27. DOI:10.1039/d6tb90072k 2026
A specific fluorescent probe for detecting endogenous butyrylcholinesterase: multi-model validation from cells to zebrafish and type 2 diabetes mellitus mice [0.03%]
一种特异检测内源性丁酰胆碱酯酶的荧光探针：从细胞到斑马鱼及二型糖尿病小鼠的多模态验证
Zhipeng Chen,Ling Huang,Qingqing Ma et al.
Zhipeng Chen et al.
Elevated butyrylcholinesterase (BChE) levels are recognized as an indicator of type 2 diabetes mellitus (T2DM), a finding supported by clinical trials. Technologies that utilize BChE as a biomarker for diagnosing T2DM are currently under de...
A cucurbit[7]uril-based upconversion nanoplatform for targeted photodynamic drug delivery [0.03%]
一种用于靶向光动力药物递送的瓜尔[7]脲上转换纳米平台
Dandan He,Zongze Duan,Guizhao Shen et al.
Dandan He et al.
Photodynamic therapy (PDT) relies on light irradiation to induce the photochemical reaction of photosensitizers to convert oxygen (O2) into highly cytotoxic reactive oxygen species (ROS). However, its therapeutic efficacy is limited by the ...
Yanliang Dong,Lei Shen,Xiaoguang Shi et al.
Yanliang Dong et al.
Hydrophobic prodrug-based microcrystalline suspensions are widely employed in long-acting injectable formulations owing to their high drug loading, minimal excipient requirements, and sustained release profiles. However, the extent to which...