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Digital light processing 3D printing of high-fidelity and versatile hydrogels via in situ phase separation [0.03%] 通过原位相分离进行高保真和多功能水凝胶的数字光处理3D打印技术
Xiang-Jun Zha,Cheng Wen,Xinyu Huang et al. Xiang-Jun Zha et al.
Recently, digital light processing (DLP) 3D printing has garnered significant interest for fabricating high-fidelity hydrogels. However, the intrinsic weak and loose network of hydrogels, coupled with uncontrollable light projection, leads ...
Injection site-retained lipid nanoparticles for targeted intramuscular delivery of mRNA RSV prefusion-F vaccine [0.03%] 用于靶向肌肉内传递mRNA RSV前融合-F疫苗的注射部位保留脂质纳米粒
Xichao Chen,Honglei Zhang,Dongyang Liu et al. Xichao Chen et al.
mRNA therapeutics, particularly mRNA vaccines, hold significant promise for a wide range of medical applications. Lipid nanoparticles (LNPs) are the most clinically advanced delivery vehicles for mRNA, but issues such as off-target effects ...
Yeast biofilm synapse: an intra-kingdom pathway to high-density current output in bioelectronic devices [0.03%] 酵母生物膜突触：生物电子设备中高密度电流输出的种内途径
Guilherme H S Ghiraldelli,Rodrigo M Iost,Graziela C Sedenho et al. Guilherme H S Ghiraldelli et al.
The quest to understand and harness microbial biofilms for energy generation has become increasingly important in the development of bioelectronic devices. Saccharomyces cerevisiae, a model organism, provides unique insights into how biofil...
Heterogeneous piezo-self-Fenton material design: an intersecting solution for pollutant degradation and tumor therapy [0.03%] 异质压电自芬顿材料设计：解决污染物降解和肿瘤治疗的交叉方案
Jiahui Cai,Jiaying Xiao,Gaoxiang Du et al. Jiahui Cai et al.
Heterogeneous piezo-self-Fenton (EPSF), an integration of piezocatalysis and heterogeneous Fenton reactions, forms the foundation for efficient redox interfacial reactions in complex environments. The significant generation of reactive oxyg...
Hybrid strengthening of cellulose nanocrystal-based solvent co-cross linked flexible organohydrogels with fast self-healing, diverse adhesive nature, and anti-freezing behavior for advanced human health monitoring [0.03%] 基于纤维素纳米晶体的溶剂共交联柔性有机水凝胶的混合强化，具有快速自愈、多种粘附特性和防冻行为，用于高级人体健康监测
Muhammad Sher,Al Nimra,Luqman Ali Shah et al. Muhammad Sher et al.
Continuous real-time monitoring of non-cognitive markers is essential for the preliminary detection, control, and regulation of long-standing health conditions. Existing diagnostic techniques are frequently invasive and often not well suite...
Enhanced catalytic efficiency of nanozymes with a V-structured chip for microfluidic biosensing of S. typhimurium [0.03%] 具有V型结构芯片的纳米酶催化效率提高，用于伤寒沙门氏菌的微流控生物传感
Ming-Yue Gao,Meng Wang,Yong-Tao Wang et al. Ming-Yue Gao et al.
Nanozymes, nanomaterials with enzyme-like characteristics which exhibit lower cost, easier synthesis and functionalization, and better stability compared with natural enzymes, have been widely developed for biosensing, disease therapy and e...
Bicheng Ake,Hongsheng Yang,Hao Yang et al. Bicheng Ake et al.
Bone defects resulting from trauma, tumors, or other injuries significantly impact human health and quality of life. However, current treatments for bone defects are constrained by donor shortages and immune rejection. Bone tissue engineeri...
Controllable mitochondrial regulation based on photo-triggered DNA circuitry [0.03%] 基于光触发DNA线路的可控线粒体调节
Songyuan Du,Longyi Zhu,Xinyi Ge et al. Songyuan Du et al.
DNA circuits have been widely used in the regulation of biomolecules and biochemical reactions due to their excellent controllability and responsiveness, but their regulation of intracellular organelles is still limited. Herein, we develop ...
Insights into nano-ZrO2 reinforced self-antibacterial Ti-3Cu composites via laser metal deposition: content-optimized bioactive nano-ZrO2 integrated for wear resistance, in vitro antibacterial and biological properties [0.03%] 基于激光金属沉积的纳米-ZrO2增强自抗菌Ti-3Cu复合材料：含量优化的生物活性纳米ZrO2集成用于耐磨损，体外抗菌和生物学性能
Ming-Chun Zhao,Zhiyong Shi,Xin Li et al. Ming-Chun Zhao et al.
Ti alloys are sensitive to fretting wear, which leads to early failure of their implants. Wear is a major factor in determining the long-term clinical performance. This work explored the increase of wear resistance in antibacterial Ti-Cu al...
Advanced 3D scaffolds for corneal stroma regeneration: a preclinical progress [0.03%] 用于角膜基质再生的高级3D支架：临床前进展
Amin Orash Mahmoudsalehi,Maryam Soleimani,Kevin Stalin Catzim Rios et al. Amin Orash Mahmoudsalehi et al.
Corneal stromal defects represent a significant global cause of blindness, necessitating innovative therapeutic strategies to address the limitations of conventional treatments, such as corneal transplantation. Tissue engineering, a corners...